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Pietro Pichierri
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The DNA crosslink‐induced S‐phase checkpoint depends on ATR–CHK1 and ATR–NBS1–FANCD2 pathways
P Pichierri, F Rosselli
The EMBO journal 23 (5), 1178-1187, 2004
2892004
ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
F Ammazzalorso, LM Pirzio, M Bignami, A Franchitto, P Pichierri
The EMBO journal 29 (18), 3156-3169, 2010
1792010
Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle
P Pichierri, A Franchitto, P Mosesso, F Palitti
Molecular biology of the cell 12 (8), 2412-2421, 2001
1622001
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle
P Pichierri, F Rosselli, A Franchitto
Oncogene 22 (10), 1491-1500, 2003
1582003
Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest
A Franchitto, P Pichierri
The Journal of cell biology 157 (1), 19-30, 2002
1482002
BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks
P Pichierri, A Franchitto, F Rosselli
The EMBO journal 23 (15), 3154-3163, 2004
1422004
Werner syndrome helicase activity is essential in maintaining fragile site stability
LM Pirzio, P Pichierri, M Bignami, A Franchitto
The Journal of cell biology 180 (2), 305-314, 2008
1312008
DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein
P Pichierri, D Averbeck, F Rosselli
Human molecular genetics 11 (21), 2531-2546, 2002
1252002
The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase
A Franchitto, P Pichierri, R Piergentili, M Crescenzi, M Bignami, F Palitti
Oncogene 22 (14), 2110-2120, 2003
1242003
Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway
A Franchitto, LM Pirzio, E Prosperi, O Sapora, M Bignami, P Pichierri
The Journal of cell biology 183 (2), 241-252, 2008
1132008
WRNIP 1 protects stalled forks from degradation and promotes fork restart after replication stress
G Leuzzi, V Marabitti, P Pichierri, A Franchitto
The EMBO journal 35 (13), 1437-1451, 2016
912016
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
E Malacaria, GM Pugliese, M Honda, V Marabitti, FA Aiello, M Spies, ...
Nature communications 10 (1), 1412, 2019
902019
Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function
I Murfuni, G Basile, S Subramanyam, E Malacaria, M Bignami, M Spies, ...
PLoS genetics 9 (10), e1003910, 2013
852013
Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells
SR Hengel, E Malacaria, L Folly da Silva Constantino, FE Bain, A Diaz, ...
Elife 5, e14740, 2016
832016
Werner’s syndrome cell lines are hypersensitive to camptothecin-induced chromosomal damage
P Pichierri, A Franchitto, P Mosesso, F Palitti
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 456 (1 …, 2000
802000
The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation
C Iannascoli, V Palermo, I Murfuni, A Franchitto, P Pichierri
Nucleic acids research 43 (20), 9788-9803, 2015
772015
Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway
M Aggarwal, T Banerjee, JA Sommers, C Iannascoli, P Pichierri, ...
Cancer research 73 (17), 5497-5507, 2013
702013
The Werner syndrome protein: linking the replication checkpoint response to genome stability
P Pichierri, F Ammazzalorso, M Bignami, A Franchitto
Aging (Albany NY) 3 (3), 311, 2011
612011
The G2-phase decatenation checkpoint is defective in Werner syndrome cells
A Franchitto, J Oshima, P Pichierri
Cancer research 63 (12), 3289-3295, 2003
602003
Fanconi anemia proteins and the s phase checkpoint
P Pichierri, F Rosselli
Cell Cycle 3 (6), 696-698, 2004
582004
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