Lactate modulation of immune responses in inflammatory versus tumour microenvironments M Certo, CH Tsai, V Pucino, PC Ho, C Mauro Nature Reviews Immunology 21 (3), 151-161, 2021 | 389 | 2021 |
Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4+ T cell metabolic rewiring V Pucino, M Certo, V Bulusu, D Cucchi, K Goldmann, E Pontarini, R Haas, ... Cell metabolism 30 (6), 1055-1074. e8, 2019 | 323 | 2019 |
Rational modulation of the innate immune system for neuroprotection in ischemic stroke D Amantea, G Micieli, C Tassorelli, MI Cuartero, I Ballesteros, M Certo, ... Frontiers in neuroscience 9, 135613, 2015 | 232 | 2015 |
Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype D Amantea, M Certo, F Petrelli, C Tassorelli, G Micieli, MT Corasaniti, ... Experimental neurology 275, 116-125, 2016 | 109 | 2016 |
Activation of RXR/PPARγ underlies neuroprotection by bexarotene in ischemic stroke M Certo, Y Endo, K Ohta, S Sakurada, G Bagetta, D Amantea Pharmacological research 102, 298-307, 2015 | 73 | 2015 |
Understanding the multifaceted role of inflammatory mediators in ischemic stroke D Amantea, C Tassorelli, F Petrelli, M Certo, P Bezzi, G Micieli, ... Current Medicinal Chemistry 21 (18), 2098-2117, 2014 | 54 | 2014 |
Metabolic checkpoints in rheumatoid arthritis V Pucino, M Certo, G Varricchi, G Marone, F Ursini, FW Rossi, A De Paulis, ... Frontiers in physiology 11, 497106, 2020 | 52 | 2020 |
Omega-3 polyunsaturated fatty acids impinge on CD4+ T cell motility and adipose tissue distribution via direct and lipid mediator-dependent effects D Cucchi, D Camacho-Munoz, M Certo, J Niven, J Smith, A Nicolaou, ... Cardiovascular research 116 (5), 1006-1020, 2020 | 52 | 2020 |
Fatty acids-from energy substrates to key regulators of cell survival, proliferation and effector function D Cucchi, D Camacho-Muñoz, M Certo, V Pucino, A Nicolaou, C Mauro Cell Stress 4 (1), 9, 2020 | 44 | 2020 |
Endothelial cell and T‐cell crosstalk: Targeting metabolism as a therapeutic approach in chronic inflammation M Certo, H Elkafrawy, V Pucino, D Cucchi, KCP Cheung, C Mauro British journal of pharmacology 178 (10), 2041-2059, 2021 | 42 | 2021 |
Selective neuronal silencing using synthetic botulinum molecules alleviates chronic pain in mice M Maiarù, C Leese, M Certo, I Echeverria-Altuna, AS Mangione, ... Science Translational Medicine 10 (450), eaar7384, 2018 | 40 | 2018 |
Early reperfusion injury is associated to MMP2 and IL-1β elevation in cortical neurons of rats subjected to middle cerebral artery occlusion D Amantea, M Certo, R Russo, G Bagetta, MT Corasaniti, C Tassorelli Neuroscience 277, 755-763, 2014 | 39 | 2014 |
Lactate: fueling the fire starter M Certo, G Marone, A de Paulis, C Mauro, V Pucino Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (3), e1474, 2020 | 37 | 2020 |
Understanding lactate sensing and signalling M Certo, A Llibre, W Lee, C Mauro Trends in Endocrinology & Metabolism 33 (10), 722-735, 2022 | 35 | 2022 |
Neuroprotective properties of a macrolide antibiotic in a mouse model of middle cerebral artery occlusion: characterization of the immunomodulatory effects and validation of … D Amantea, M Certo, F Petrelli, G Bagetta Assay and Drug Development Technologies 14 (5), 298-307, 2016 | 26 | 2016 |
Neuroprotection by the PARP inhibitor PJ34 modulates cerebral and circulating RAGE levels in rats exposed to focal brain ischemia R Greco, C Tassorelli, AS Mangione, G Levandis, M Certo, G Nappi, ... European journal of pharmacology 744, 91-97, 2014 | 23 | 2014 |
Caspase-1-independent Maturation of IL-1ββ in Ischemic Brain Injury: is there a Role for Gelatinases? D Amantea, R Russo, M Certo, L Rombolà, A Adornetto, L A Morrone, ... Mini reviews in medicinal chemistry 16 (9), 729-737, 2016 | 21 | 2016 |
Differential metabotypes in synovial fibroblasts and synovial fluid in hip osteoarthritis patients support inflammatory responses H Farah, SN Wijesinghe, T Nicholson, F Alnajjar, M Certo, A Alghamdi, ... International journal of molecular sciences 23 (6), 3266, 2022 | 18 | 2022 |
Understanding the role of host metabolites in the induction of immune senescence: Future strategies for keeping the ageing population healthy J Conway, M Certo, JM Lord, C Mauro, NA Duggal British journal of pharmacology 179 (9), 1808-1824, 2022 | 14 | 2022 |
Tolerogenic effects of 1, 25-dihydroxyvitamin D on dendritic cells involve induction of fatty acid synthesis AM Garcia, EL Bishop, D Li, LE Jeffery, A Garten, A Thakker, M Certo, ... The Journal of Steroid Biochemistry and Molecular Biology 211, 105891, 2021 | 13 | 2021 |