| Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216 CY Peng, PR Graves, RS Thoma, Z Wu, AS Shaw, H Piwnica-Worms Science 277 (5331), 1501-1505, 1997 | 1844 | 1997 |
| Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25 Y Sanchez, C Wong, RS Thoma, R Richman, Z Wu, H Piwnica-Worms, ... Science 277 (5331), 1497-1501, 1997 | 1749 | 1997 |
| ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 HUI Zhao, H Piwnica-Worms Molecular and cellular biology, 2001 | 1321 | 2001 |
| Whole-genome analysis informs breast cancer response to aromatase inhibition MJ Ellis, L Ding, D Shen, J Luo, VJ Suman, JW Wallis, BA Van Tine, ... Nature 486 (7403), 353-360, 2012 | 1200 | 2012 |
| The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. JA DeCaprio, JW Ludlow, D Lynch, Y Furukawa, J Griffin, ... Cell 58 (6), 1085, 1989 | 1191 | 1989 |
| Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. LL Parker, H Piwnica-Worms Science (New York, NY) 257 (5078), 1955, 1992 | 929 | 1992 |
| Use of an oriented peptide library to determine the optimal substrates of protein kinases. Z Songyang, S Blechner, N Hoagland, MF Hoekstra, H Piwnica-Worms, ... Current biology: CB 4 (11), 973, 1994 | 830 | 1994 |
| The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01 PR Graves, L Yu, JK Schwarz, J Gales, EA Sausville, PM O'Connor, ... Journal of Biological Chemistry 275 (8), 5600-5605, 2000 | 688 | 2000 |
| Abnormal Alzheimer‐like phosphorylation of tau‐protein by cyclin‐dependent kinases cdk2 and cdk5 K Baumann, EM Mandelkow, J Biernat, H Piwnica-Worms, E Mandelkow FEBS letters 336 (3), 417-424, 1993 | 652 | 1993 |
| Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src. H Piwnica-Worms, KB Saunders, TM Roberts, AE Smith, SH Cheng Cell 49 (1), 75, 1987 | 613 | 1987 |
| Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints H Zhao, JL Watkins, H Piwnica-Worms Proceedings of the National Academy of Sciences 99 (23), 14795-14800, 2002 | 597 | 2002 |
| Metformin promotes antitumor immunity via endoplasmic-reticulum-associated degradation of PD-L1 JH Cha, WH Yang, W Xia, Y Wei, LC Chan, SO Lim, CW Li, T Kim, ... Molecular cell 71 (4), 606-620. e7, 2018 | 563 | 2018 |
| Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation JY Ahn, JK Schwarz, H Piwnica-Worms, CE Canman Cancer research 60 (21), 5934-5936, 2000 | 556 | 2000 |
| Kinetics of regulated protein–protein interactions revealed with firefly luciferase complementation imaging in cells and living animals KE Luker, MCP Smith, GD Luker, ST Gammon, H Piwnica-Worms, ... Proceedings of the National Academy of Sciences 101 (33), 12288-12293, 2004 | 519 | 2004 |
| The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex F Liu, JJ Stanton, Z Wu, H Piwnica-Worms Molecular and cellular biology 17 (2), 571-583, 1997 | 479 | 1997 |
| Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1 Y Zeng, KC Forbes, Z Wu, S Moreno, H Piwnica-Worms, T Enoch Nature 395 (6701), 507-510, 1998 | 455 | 1998 |
| Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation M Xu, KA Sheppard, CY Peng, AS Yee, H Piwnica-Worms Molecular and cellular biology 14 (12), 8420-8431, 1994 | 414 | 1994 |
| Lack of PTEN sequesters CHK1 and initiates genetic instability J Puc, M Keniry, HS Li, TK Pandita, AD Choudhury, L Memeo, ... Cancer cell 7 (2), 193-204, 2005 | 408 | 2005 |
| p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15. LL Parker, S Atherton-Fessler, H Piwnica-Worms Proceedings of the National Academy of Sciences 89 (7), 2917-2921, 1992 | 390 | 1992 |
| Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A EB Fauman, JP Cogswell, B Lovejoy, WJ Rocque, W Holmes, ... Cell 93 (4), 617-625, 1998 | 387 | 1998 |
alastair m thompsonProfessor of Surgical OncologyEmail verificata su dundee.ac.uk
