|Mammalian caspases: structure, activation, substrates, and functions during apoptosis|
WC Earnshaw, LM Martins, SH Kaufmann
Annual review of biochemistry 68 (1), 383-424, 1999
|The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif|
LM Martins, I Iaccarino, T Tenev, S Gschmeissner, NF Totty, NR Lemoine, ...
Journal of Biological Chemistry 277 (1), 439-444, 2002
|Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease|
KM Strauss, LM Martins, H Plun-Favreau, FP Marx, S Kautzmann, D Berg, ...
Human molecular genetics 14 (15), 2099-2111, 2005
|The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1|
H Plun-Favreau, K Klupsch, N Moisoi, S Gandhi, S Kjaer, D Frith, ...
Nature cell biology 9 (11), 1243, 2007
|Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice|
LM Martins, A Morrison, K Klupsch, V Fedele, N Moisoi, P Teismann, ...
Molecular and cellular biology 24 (22), 9848-9862, 2004
|The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner|
J Zhao, T Tenev, LM Martins, J Downward, NR Lemoine
Journal of cell science 113 (23), 4363-4371, 2000
|Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions|
CM Eischen, TJ Kottke, LM Martins, GS Basi, JS Tung, WC Earnshaw, ...
Blood 90 (3), 935-943, 1997
|PINK1 cleavage at position A103 by the mitochondrial protease PARL|
E Deas, H Plun-Favreau, S Gandhi, H Desmond, S Kjaer, SHY Loh, ...
Human molecular genetics 20 (5), 867-879, 2010
|Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis|
M Rytömaa, LM Martins, J Downward
Current Biology 9 (18), 1043-S2, 1999
|Activation of multiple interleukin-1β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis|
LM Martins, T Kottke, PW Mesner, GS Basi, S Sinha, N Frigon, E Tatar, ...
Journal of Biological Chemistry 272 (11), 7421-7430, 1997
|Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells|
RT Lima, LM Martins, JE Guimaraes, C Sambade, MH Vasconcelos
Cancer gene therapy 11 (5), 309, 2004
|The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death|
S Baksh, S Tommasi, S Fenton, CY Victor, LM Martins, GP Pfeifer, F Latif, ...
Molecular cell 18 (6), 637-650, 2005
|Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis|
LM Martins, PW Mesner, TJ Kottke, GS Basi, S Sinha, JS Tung, ...
Blood 90 (11), 4283-4296, 1997
|Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response|
N Moisoi, K Klupsch, V Fedele, P East, S Sharma, A Renton, ...
Cell death and differentiation 16 (3), 449, 2009
|Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution|
K Samejima, S Toné, TJ Kottke, M Enari, H Sakahira, CA Cooke, ...
The Journal of cell biology 143 (1), 225-239, 1998
|Apoptosis: alive and kicking in 1997|
LM Martins, WC Earnshaw
Trends in cell biology 7 (3), 111-114, 1997
|Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi|
LM Martins, BE Turk, V Cowling, A Borg, ET Jarrell, LC Cantley, ...
Journal of Biological Chemistry 278 (49), 49417-49427, 2003
|Cancer and neurodegeneration: between the devil and the deep blue sea|
H Plun-Favreau, PA Lewis, J Hardy, LM Martins, NW Wood
PLoS genetics 6 (12), e1001257, 2010
|Comparison of Paclitaxel-, 5-Fluoro-2′-deoxyuridine-, and Epidermal Growth Factor (EGF)-induced Apoptosis evidence for egf-induced anoikis|
TJ Kottke, AL Blajeski, LM Martins, PW Mesner, NE Davidson, ...
Journal of Biological Chemistry 274 (22), 15927-15936, 1999
|Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster|
IP De Castro, AC Costa, D Lam, R Tufi, V Fedele, N Moisoi, D Dinsdale, ...
Cell death and differentiation 19 (8), 1308, 2012