Shawn Hingtgen
Shawn Hingtgen
Associate Professor, UNC Chapel Hill Eshelman School of Pharmacy
Verified email at - Homepage
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Cited by
Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells
MS Kim, MJ Haney, Y Zhao, V Mahajan, I Deygen, NL Klyachko, E Inskoe, ...
Nanomedicine: Nanotechnology, Biology and Medicine 12 (3), 655-664, 2016
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy
LS Sasportas, R Kasmieh, H Wakimoto, S Hingtgen, JAJM van de Water, ...
Proceedings of the national academy of sciences 106 (12), 4822-4827, 2009
Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas
TM Kauer, JL Figueiredo, S Hingtgen, K Shah
Nature neuroscience 15 (2), 197-204, 2012
Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy
SD Hingtgen, X Tian, J Yang, SM Dunlay, AS Peek, Y Wu, RV Sharma, ...
Physiological genomics 26 (3), 180-191, 2006
Specific transfection of inflamed brain by macrophages: a new therapeutic strategy for neurodegenerative diseases
MJ Haney, Y Zhao, EB Harrison, V Mahajan, S Ahmed, Z He, P Suresh, ...
PloS one 8 (4), e61852, 2013
Stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy
M Duebgen, J Martinez-Quintanilla, K Tamura, S Hingtgen, N Redjal, ...
Journal of the national cancer institute 106 (6), dju090, 2014
Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma
JR Bagó, A Alfonso-Pecchio, O Okolie, R Dumitru, A Rinkenbaugh, ...
Nature communications 7 (1), 10593, 2016
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model
K Shah, S Hingtgen, R Kasmieh, JL Figueiredo, E Garcia-Garcia, ...
Journal of Neuroscience 28 (17), 4406-4413, 2008
Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model
O Okolie, JR Bago, RS Schmid, DM Irvin, RE Bash, CR Miller, ...
Neuro-oncology 18 (12), 1622-1633, 2016
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide
S Hingtgen, X Ren, E Terwilliger, M Classon, R Weissleder, K Shah
Molecular cancer therapeutics 7 (11), 3575-3585, 2008
Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins
NL Klyachko, MJ Haney, Y Zhao, DS Manickam, V Mahajan, P Suresh, ...
Nanomedicine 9 (9), 1403-1422, 2014
Tumor-homing cytotoxic human induced neural stem cells for cancer therapy
JR Bagó, O Okolie, R Dumitru, MG Ewend, JS Parker, RV Werff, ...
Science translational medicine 9 (375), eaah6510, 2017
Engineered mesenchymal stem cell/nanomedicine spheroid as an active drug delivery platform for combinational glioblastoma therapy
S Suryaprakash, YH Lao, HY Cho, M Li, HY Ji, D Shao, H Hu, CH Quek, ...
Nano Letters 19 (3), 1701-1705, 2019
Electrospun nanofibrous scaffolds increase the efficacy of stem cell-mediated therapy of surgically resected glioblastoma
JR Bagó, GJ Pegna, O Okolie, M Mohiti-Asli, EG Loboa, SD Hingtgen
Biomaterials 90, 116-125, 2016
Neural stem cell therapy for cancer
JR Bagó, KT Sheets, SD Hingtgen
Methods 99, 37-43, 2016
A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy
SD Hingtgen, R Kasmieh, J van de Water, R Weissleder, K Shah
Stem Cells 28 (4), 832-841, 2010
Real-time multi-modality imaging of glioblastoma tumor resection and recurrence
S Hingtgen, JL Figueiredo, C Farrar, M Duebgen, J Martinez-Quintanilla, ...
Journal of neuro-oncology 111, 153-161, 2013
Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo
E Arwert, S Hingtgen, JL Figueiredo, H Bergquist, U Mahmood, ...
Cancer research 67 (15), 7335-7342, 2007
Sustained delivery of doxorubicin via acetalated dextran scaffold prevents glioblastoma recurrence after surgical resection
E Graham-Gurysh, KM Moore, AB Satterlee, KT Sheets, FC Lin, ...
Molecular pharmaceutics 15 (3), 1309-1318, 2018
Engineering toxin-resistant therapeutic stem cells to treat brain tumors
DW Stuckey, SD Hingtgen, N Karakas, BE Rich, K Shah
Stem cells 33 (2), 589-600, 2015
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