| α-Synuclein interacts with glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases TL Yap, JM Gruschus, A Velayati, W Westbroek, E Goldin, N Moaven, ... Journal of Biological Chemistry, jbc. M111. 237859, 2011 | 214 | 2011 |
| Phosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1: evidence for the pleckstrin homology domain functioning as an allosteric site JL Kam, K Miura, TR Jackson, J Gruschus, P Roller, S Stauffer, J Clark, ... Journal of Biological Chemistry 275 (13), 9653-9663, 2000 | 149 | 2000 |
| Observation of a narrow superconducting transition at 6 GHz in crystals of Y DL Rubin, K Green, J Gruschus, J Kirchgessner, D Moffat, H Padamsee, ... Physical Review B 38 (10), 6538, 1988 | 125 | 1988 |
| New Hamiltonian model for long-range electronic superexchange in complex molecular structures JM Gruschus, A Kuki The Journal of Physical Chemistry 97 (21), 5581-5593, 1993 | 115 | 1993 |
| Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity JM Gruschus, DHH Tsao, LH Wang, M Nirenberg, JA Ferretti Biochemistry 36 (18), 5372-5380, 1997 | 103 | 1997 |
| Histone H4 K16Q mutation, an acetylation mimic, causes structural disorder of its N-terminal basic patch in the nucleosome BR Zhou, H Feng, R Ghirlando, H Kato, J Gruschus, Y Bai Journal of molecular biology 421 (1), 30-37, 2012 | 96 | 2012 |
| The Three-dimensional Solution Structure of the NK-2 Homeodomain fromDrosophila DHH Tsao, JM Gruschus, LH Wang, M Nirenberg, JA Ferretti Journal of molecular biology 251 (2), 297-307, 1995 | 83 | 1995 |
| Elongation of helix III of the NK-2 homeodomain upon binding to DNA: a secondary structure study by NMR DHH Tsao, JM Gruschus, LH Wang, M Nirenberg, JA Ferretti Biochemistry 33 (50), 15053-15060, 1994 | 82 | 1994 |
| Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1 X Jian, P Brown, P Schuck, JM Gruschus, A Balbo, JE Hinshaw, ... Journal of biological chemistry 284 (3), 1652-1663, 2009 | 79 | 2009 |
| Germ-line mutation of NKX3. 1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function SL Zheng, J Ju, B Chang, E Ortner, J Sun, SD Isaacs, J Sun, KE Wiley, ... Cancer research 66 (1), 69-77, 2006 | 64 | 2006 |
| Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy TL Yap, Z Jiang, F Heinrich, JM Gruschus, CM Pfefferkorn, M Barros, ... Journal of Biological Chemistry 290 (2), 744-754, 2015 | 60 | 2015 |
| Modifications to the C‐terminus of Arf1 alter cell functions and protein interactions X Jian, M Cavenagh, JM Gruschus, PA Randazzo, RA Kahn Traffic 11 (6), 732-742, 2010 | 59 | 2010 |
| Molecular basis for cooperative binding of anionic phospholipids to the PH domain of the Arf GAP ASAP1 X Jian, WK Tang, P Zhai, NS Roy, R Luo, JM Gruschus, ME Yohe, ... Structure 23 (11), 1977-1988, 2015 | 58 | 2015 |
| The three-dimensional structure of the vnd/NK-2 homeodomain-DNA complex by NMR spectroscopy JM Gruschus, DHH Tsao, LH Wang, M Nirenberg, JA Ferretti Journal of molecular biology 289 (3), 529-545, 1999 | 57 | 1999 |
| Saposin C protects glucocerebrosidase against α-synuclein inhibition TL Yap, JM Gruschus, A Velayati, E Sidransky, JC Lee Biochemistry 52 (41), 7161-7163, 2013 | 55 | 2013 |
| Site-directed mutations in the vnd/nk-2 homeodomain: basis of variations in structure and sequence-specific DNA binding S Weiler, JM Gruschus, DHH Tsao, L Yu, LH Wang, M Nirenberg, ... Journal of Biological Chemistry 273 (18), 10994-11000, 1998 | 53 | 1998 |
| Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains MM Che, ES Boja, HY Yoon, J Gruschus, H Jaffe, S Stauffer, P Schuck, ... Cellular signalling 17 (10), 1276-1288, 2005 | 43 | 2005 |
| Characterization of the N-terminal tail domain of histone H3 in condensed nucleosome arrays by hydrogen exchange and NMR H Kato, J Gruschus, R Ghirlando, N Tjandra, Y Bai Journal of the American Chemical Society 131 (42), 15104-15105, 2009 | 42 | 2009 |
| A low pKa cysteine at the active site of mouse methionine sulfoxide reductase A JC Lim, JM Gruschus, G Kim, BS Berlett, N Tjandra, RL Levine Journal of Biological Chemistry 287 (30), 25596-25601, 2012 | 41 | 2012 |
| The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site X Jian, JM Gruschus, E Sztul, PA Randazzo Journal of Biological Chemistry 287 (29), 24273-24283, 2012 | 41 | 2012 |
