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James J. Knittel
James J. Knittel
Professor of Medicinal Chemistry, Western New England University
Verified email at wne.edu
Title
Cited by
Cited by
Year
Membrane cholesterol dynamics: cholesterol domains and kinetic pools
F Schroeder, JR Jefferson, AB Kier, J Knittel, TJ Scallen, WG Wood, ...
Proceedings of the Society for Experimental Biology and Medicine 196 (3 …, 1991
3561991
The Melanocortin 1 Receptor and the UV Response of Human Melanocytes—A Shift in Paradigm
ZA Abdel‐Malek, J Knittel, AL Kadekaro, VB Swope, R Starner
Photochemistry and photobiology 84 (2), 501-508, 2008
1582008
α‐MSH tripeptide analogs activate the melanocortin 1 receptor and reduce UV‐induced DNA damage in human melanocytes
ZA Abdel‐Malek, A Ruwe, R Kavanagh‐Starner, AL Kadekaro, V Swope, ...
Pigment cell & melanoma research 22 (5), 635-644, 2009
1062009
Melanoma prevention strategy based on using tetrapeptide α‐MSH analogs that protect human melanocytes from UV‐induced DNA damage and cytotoxicity
ZA Abdel-Malek, AL Kadekaro, RJ Kavanagh, A Todorovic, LN Koikov, ...
The FASEB journal 20 (9), 1561-1563, 2006
1002006
Neuropeptide Y (NPY) Y4 Receptor Selective Agonists Based on NPY(32−36):  Development of an Anorectic Y4 Receptor Selective Agonist with Picomolar Affinity
A Balasubramaniam, DE Mullins, S Lin, W Zhai, Z Tao, VC Dhawan, ...
Journal of medicinal chemistry 49 (8), 2661-2665, 2006
772006
Cyclic melanotropins. 9. 7-D-Phenylalanine analogues of the active-site sequence
WL Cody, M Mahoney, JJ Knittel, VJ Hruby, AML Castrucci, ME Hadley
Journal of medicinal chemistry 28 (5), 583-588, 1985
771985
Structure-activity studies of highly potent cyclic [Cys4, Cys10] melanotropin analogs
JJ Knittel, TK Sawyer, VJ Hruby, ME Hadley
Journal of Medicinal Chemistry 26 (2), 125-129, 1983
701983
Sub-nanomolar hMC1R agonists by end-capping of the melanocortin tetrapeptide His-D-Phe-Arg-Trp-NH2
LN Koikov, FH Ebetino, MG Solinsky, D Cross-Doersen, JJ Knittel
Bioorganic & medicinal chemistry letters 13 (16), 2647-2650, 2003
532003
Synthesis and biological actions of highly potent and prolonged acting biotin-labeled melanotropins
DN Chaturvedi, JJ Knittel, VJ Hruby, AML Castrucci, ME Hadley
Journal of medicinal chemistry 27 (11), 1406-1410, 1984
451984
The conformational analysis of aromatic methoxyl groups from carbon-13 chemical shifts and spin-lattice relaxation times
A Makriyannis, JJ Knittel
Tetrahedron Letters 20 (30), 2753-2756, 1979
431979
Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS‐1 cells: The possible contribution of 86Rb+ efflux and 45Ca2+ uptake
M Töpfer, CE Burbiel, CE Müller, J Knittel, EJ Verspohl
Cell Biochemistry and Function: Cellular biochemistry and its modulation by …, 2008
422008
Development and use of hydrophobic surface area (hsa) descriptors for computer-assisted quantitative structure− activity and structure− property relationship studies
DT Stanton, BE Mattioni, JJ Knittel, PC Jurs
Journal of chemical information and computer sciences 44 (3), 1010-1023, 2004
412004
Conformational and dynamic considerations in the design of peptide hormone analogs
VJ Hruby, HI Mosberg, TK Sawyer, JJ Knittel, TW Rockway, J Ormberg, ...
Biopolymers: Original Research on Biomolecules 22 (1), 517-530, 1983
361983
Studies on phenethylamine hallucinogens. 2. Conformations of arylmethoxyl groups by carbon-13 NMR
JJ Knittel, A Makriyannis
Journal of Medicinal Chemistry 24 (7), 906-909, 1981
311981
Analogs of sub-nanomolar hMC1R agonist LK-184 [Ph (CH2) 3CO-His-D-Phe-Arg-Trp-NH2]. An additional binding site within the human melanocortin receptor 1?
LN Koikov, FH Ebetino, MG Solinsky, D Cross-Doersen, JJ Knittel
Bioorganic & medicinal chemistry letters 14 (15), 3997-4000, 2004
302004
Structural and conformational modifications of α-MSH/ACTH4–10 provide melanotropin analogues with highly potent behavioral activities
MD Hirsch, TL O'Donohue, R Wilson, TK Sawyer, VJ Hruby, ME Hadley, ...
Peptides 5 (6), 1197-1201, 1984
301984
Mechanistic studies of sterol carrier protein-2 effects on L-cell fibroblast plasma membrane sterol domains
JK Woodford, I Hapala, JR Jefferson, JJ Knittel, J Kavecansky, D Powell, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1189 (1), 52-60, 1994
241994
End-capping of the modified melanocortin tetrapeptide (p-Cl) Phe-D-Phe-Arg-Trp-NH2 as a route to hMC4R agonists
LN Koikov, FH Ebetino, JC Hayes, D Cross-Doersen, JJ Knittel
Bioorganic & medicinal chemistry letters 14 (19), 4839-4842, 2004
182004
Pancreastatin inhibits insulin secretion in RINm5F cells through obstruction of G-protein mediated, calcium-directed exocytosis
ZI Hertelendy, DG Patel, JJ Knittel
Cell Calcium 19 (2), 125-132, 1996
181996
Drug design and relationship of functional groups to pharmacologic activity
RM Zavod, JJ Knittel
Foye’s Principles of Medicinal Chemistry, 7th ed.; Lemke, T., Williams, DA …, 2008
172008
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