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Nancie J. MacIver
Nancie J. MacIver
Pediatric Endocrinology Division Chief, University of North Carolina at Chapel Hill
Email verificata su med.unc.edu
Titolo
Citata da
Citata da
Anno
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
RD Michalek, VA Gerriets, SR Jacobs, AN Macintyre, NJ MacIver, ...
The Journal of immunology 186 (6), 3299-3303, 2011
20562011
Metabolic regulation of T lymphocytes
NJ MacIver, RD Michalek, JC Rathmell
Annual review of immunology 31, 259-283, 2013
12852013
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways
SR Jacobs, CE Herman, NJ MacIver, JA Wofford, HL Wieman, ...
The Journal of Immunology 180 (7), 4476-4486, 2008
9062008
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ...
The Journal of clinical investigation 125 (1), 194-207, 2015
6642015
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
NJ MacIver, SR Jacobs, HL Wieman, JA Wofford, JL Coloff, JC Rathmell
Journal of Leucocyte Biology 84 (4), 949-957, 2008
5782008
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
VA Gerriets, RJ Kishton, MO Johnson, S Cohen, PJ Siska, AG Nichols, ...
Nature immunology 17 (12), 1459-1466, 2016
4702016
Changes in nutritional status impact immune cell metabolism and function
Y Alwarawrah, K Kiernan, NJ MacIver
Frontiers in immunology 9, 337099, 2018
4632018
RelB cellular regulation and transcriptional activity are regulated by p100
NJ Solan, H Miyoshi, EM Carmona, GD Bren, CV Paya
Journal of Biological Chemistry 277 (2), 1405-1418, 2002
3342002
Transcription of the RelB gene is regulated by NF-κB
GD Bren, NJ Solan, H Miyoshi, KN Pennington, LJ Pobst, CV Paya
Oncogene 20 (53), 7722-7733, 2001
2722001
Leptin metabolically licenses T cells for activation to link nutrition and immunity
DC Saucillo, VA Gerriets, J Sheng, JC Rathmell, NJ MacIver
The Journal of Immunology 192 (1), 136-144, 2014
2692014
The liver kinase B1 is a central regulator of T cell development, activation, and metabolism
NJ MacIver, J Blagih, DC Saucillo, L Tonelli, T Griss, JC Rathmell, ...
The Journal of Immunology 187 (8), 4187-4198, 2011
2572011
Nutritional effects on T‐cell immunometabolism
S Cohen, K Danzaki, NJ MacIver
European journal of immunology 47 (2), 225-235, 2017
1772017
Role of T cells in malnutrition and obesity
VA Gerriets, NJ MacIver
Frontiers in Immunology 5, 105102, 2014
1592014
Suppression of Glut1 and glucose metabolism by decreased Akt/mTORC1 signaling drives T cell impairment in B cell leukemia
PJ Siska, GJW van der Windt, RJ Kishton, S Cohen, W Eisner, NJ MacIver, ...
The Journal of Immunology 197 (6), 2532-2540, 2016
1442016
Leptin directly promotes T‐cell glycolytic metabolism to drive effector T‐cell differentiation in a mouse model of autoimmunity
VA Gerriets, K Danzaki, RJ Kishton, W Eisner, AG Nichols, DC Saucillo, ...
European journal of immunology 46 (8), 1970-1983, 2016
1142016
The role of the adipokine leptin in immune cell function in health and disease
K Kiernan, NJ MacIver
Frontiers in immunology 11, 622468, 2021
952021
Systematic dissection of the metabolic-apoptotic interface in AML reveals heme biosynthesis to be a regulator of drug sensitivity
KH Lin, A Xie, JC Rutter, Y Ahn, JM Lloyd-Cowden, AG Nichols, ...
Cell metabolism 29 (5), 1217-1231. e7, 2019
882019
Obesity-induced changes in T-cell metabolism are associated with impaired memory T-cell response to influenza and are not reversed with weight loss
J Rebeles, WD Green, Y Alwarawrah, AG Nichols, W Eisner, K Danzaki, ...
The Journal of Infectious Diseases 219 (10), 1652-1661, 2019
722019
Dominant Splice Site Mutations in PIK3R1 Cause Hyper IgM Syndrome, Lymphadenopathy and Short Stature
S Petrovski, RE Parrott, JL Roberts, H Huang, J Yang, B Gorentla, ...
Journal of clinical immunology 36, 462-471, 2016
572016
Functional heterogeneity of alveolar macrophage population based on expression of CXCL2
S Xu-Vanpala, ME Deerhake, JD Wheaton, ME Parker, PR Juvvadi, ...
Science immunology 5 (50), eaba7350, 2020
502020
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