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Ricardo Serrano
Ricardo Serrano
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High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells
A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ...
Science translational medicine 9 (377), eaaf2584, 2017
3472017
Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes
DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ...
Cell reports 32 (3), 107925, 2020
2422020
Use of human induced pluripotent stem cell–derived cardiomyocytes to assess drug cardiotoxicity
A Sharma, WL McKeithan, R Serrano, T Kitani, PW Burridge, ...
Nature protocols 13 (12), 3018-3041, 2018
1352018
High throughput physiological screening of iPSC-derived cardiomyocytes for drug development
JC del Álamo, D Lemons, R Serrano, A Savchenko, F Cerignoli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1717-1727, 2016
1312016
Rickettsia Sca4 reduces vinculin-mediated intercellular tension to promote spread
RL Lamason, E Bastounis, NM Kafai, R Serrano, JC Del Álamo, ...
Cell 167 (3), 670-683. e10, 2016
1012016
Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis
YT Yeh, R Serrano, J François, JJ Chiu, YSJ Li, JC Del Álamo, S Chien, ...
Proceedings of the National Academy of Sciences 115 (1), 133-138, 2018
652018
Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling
I Banerjee, K Carrion, R Serrano, J Dyo, R Sasik, S Lund, E Willems, ...
Journal of molecular and cellular cardiology 79, 133-144, 2015
642015
Reengineering an antiarrhythmic drug using patient hiPSC cardiomyocytes to improve therapeutic potential and reduce toxicity
WL McKeithan, DAM Feyen, AAN Bruyneel, KJ Okolotowicz, DA Ryan, ...
Cell Stem Cell 27 (5), 813-821. e6, 2020
372020
Three-dimensional monolayer stress microscopy
R Serrano, A Aung, YT Yeh, S Varghese, JC Lasheras, JC del Álamo
Biophysical journal 117 (1), 111-128, 2019
372019
MiR-145 mediates cell morphology-regulated mesenchymal stem cell differentiation to smooth muscle cells
YT Yeh, J Wei, S Thorossian, K Nguyen, C Hoffman, JC del Álamo, ...
Biomaterials 204, 59-69, 2019
372019
Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming
M Gálvez-Santisteban, D Chen, R Zhang, R Serrano, C Nguyen, L Zhao, ...
eLife 8, e44816, 2019
302019
miR-486 is modulated by stretch and increases ventricular growth
S Lange, I Banerjee, K Carrion, R Serrano, L Habich, R Kameny, ...
JCI insight, 2019
272019
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy
I Perea-Gil, T Seeger, AAN Bruyneel, V Termglinchan, E Monte, EW Lim, ...
European Heart Journal 43 (36), 3477-3489, 2022
262022
A novel recessive mutation in SPEG causes early onset dilated cardiomyopathy
A Levitas, E Muhammad, Y Zhang, I Perea Gil, R Serrano, N Diaz, ...
PLoS genetics 16 (9), e1009000, 2020
262020
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Sci Transl Med 9
A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ...
Epub 2017/02/17. 10.1126/scitranslmed. aaf2584, 2017
192017
Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes. Cell Rep 32: 107925
DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ...
122020
A Multi-well Format Polyacrylamide-based Assay for Studying the Effect of Extracellular Matrix Stiffness on the Bacterial Infection of Adherent Cells
EE Bastounis, FE Ortega, R Serrano, JA Theriot
JoVE (Journal of Visualized Experiments), e57361, 2018
82018
Reengineering Ponatinib to Minimize Cardiovascular Toxicity.
AP Hnatiuk, AAN Bruyneel, D Tailor, M Pandrala, A Dheeraj, W Li, ...
Cancer Research, canres. CAN-21, 2022
72022
A deep learning platform to assess drug proarrhythmia risk
R Serrano, DAM Feyen, AAN Bruyneel, AP Hnatiuk, MM Vu, PL Amatya, ...
Cell Stem Cell, 2022
62022
Early committed polarization of intracellular tension in response to cell shape determines the osteogenic differentiation of mesenchymal stromal cells
MC Wu, HW Yu, YQ Chen, MH Ou, R Serrano, GL Huang, YK Wang, K Lin, ...
Acta Biomaterialia, 2022
42022
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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