Distinct chromatin signatures of DNA hypomethylation in aging and cancer RF Perez, JR Tejedor, GF Bayon, AF Fernández, MF Fraga Aging Cell 17 (3), e12744, 2018 | 88 | 2018 |
Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes RF Pérez, P Santamarina, JR Tejedor, RG Urdinguio, J Álvarez-Pitti, ... Journal of translational medicine 17, 1-16, 2019 | 58 | 2019 |
Epigenetic downregulation of TET3 reduces genome‐wide 5hmC levels and promotes glioblastoma tumorigenesis A Carella, JR Tejedor, MG García, RG Urdinguio, GF Bayón, M Sierra, ... International journal of cancer 146 (2), 373-387, 2020 | 55 | 2020 |
Discovery of reversible DNA methyltransferase and lysine methyltransferase G9a inhibitors with antitumoral in vivo efficacy O Rabal, E San Jose-Eneriz, X Agirre, JA Sánchez-Arias, A Vilas-Zornoza, ... Journal of Medicinal Chemistry 61 (15), 6518-6545, 2018 | 38 | 2018 |
Epigenetic dysregulation of TET2 in human glioblastoma MG García, A Carella, RG Urdinguio, GF Bayón, V Lopez, JR Tejedor, ... Oncotarget 9 (40), 25922, 2018 | 34 | 2018 |
Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma AF Fernandez, GF Bayón, MI Sierra, RG Urdinguio, EG Toraño, ... Human Molecular Genetics 27 (17), 3046-3059, 2018 | 30 | 2018 |
Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment RG Urdinguio, V Lopez, GF Bayon, R Diaz de la Guardia, MI Sierra, ... Nucleic acids research 47 (10), 5016-5037, 2019 | 26 | 2019 |
Aging and cancer epigenetics: Where do the paths fork? RF Pérez, JR Tejedor, AF Fernández, MF Fraga Aging Cell 21 (10), e13709, 2022 | 16 | 2022 |
Blood DNA methylation patterns in older adults with evolving dementia RF Pérez, JJ Alba-Linares, JR Tejedor, AF Fernández, M Calero, ... The Journals of Gerontology: Series A 77 (9), 1743-1749, 2022 | 15 | 2022 |
Physical exercise shapes the mouse brain epigenome RG Urdinguio, JR Tejedor, M Fernández-Sanjurjo, RF Pérez, A Peñarroya, ... Molecular metabolism 54, 101398, 2021 | 15 | 2021 |
SDHC Promoter Methylation, a Novel Pathogenic Mechanism in Parasympathetic Paragangliomas C Bernardo-Castiñeira, N Valdés, MI Sierra, I Sáenz-de-Santa-María, ... The Journal of Clinical Endocrinology & Metabolism 103 (1), 295-305, 2018 | 15 | 2018 |
Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL-rearranged B cell acute lymphoblastic leukemia JR Tejedor, C Bueno, M Vinyoles, P Petazzi, A Agraz-Doblas, I Cobo, ... The Journal of Clinical Investigation 131 (13), 2021 | 14 | 2021 |
Epigenome-wide analysis reveals specific DNA hypermethylation of T cells during human hematopoietic differentiation JR Tejedor, C Bueno, I Cobo, GF Bayón, C Prieto, C Mangas, RF Pérez, ... Epigenomics 10 (7), 903-923, 2018 | 14 | 2018 |
Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways JJ Alba-Linares, RF Pérez, JR Tejedor, D Bastante-Rodríguez, F Ponce, ... Cardiovascular Diabetology 22 (1), 44, 2023 | 10 | 2023 |
Epigenetic Deregulation of the Histone Methyltransferase KMT5B Contributes to Malignant Transformation in Glioblastoma V López, JR Tejedor, A Carella, MG García, P Santamarina-Ojeda, ... Frontiers in cell and developmental biology 9, 671838, 2021 | 8 | 2021 |
Autophagy deficiency by Atg4B loss leads to metabolomic alterations in mice GG Martínez-García, RF Pérez, ÁF Fernández, S Durand, G Kroemer, ... Metabolites 11 (8), 481, 2021 | 8 | 2021 |
Epigenetics and lifestyle: the impact of stress, diet, and social habits on tissue homeostasis RF Pérez, P Santamarina, AF Fernández, MF Fraga Epigenetics and Regeneration, 461-489, 2019 | 8 | 2019 |
Conservation of aging and cancer epigenetic signatures across human and mouse RF Pérez, JR Tejedor, P Santamarina-Ojeda, V López, RG Urdinguio, ... Molecular Biology and Evolution, 2021 | 6 | 2021 |
No genome-wide DNA methylation changes found associated with medium-term reduced graphene oxide exposure in human lung epithelial cells RF Pérez, AY Soto Fernández, P Bousquets Muñoz, MI Sierra, JR Tejedor, ... Epigenetics 15 (3), 283-293, 2020 | 5 | 2020 |
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer JR Tejedor, A Peñarroya, J Gancedo-Verdejo, P Santamarina-Ojeda, ... Clinical Epigenetics 15 (1), 133, 2023 | 2 | 2023 |