SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli, CJ Zhang, ... Science immunology 6 (58), eabg0833, 2021 | 149 | 2021 |
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells D Chauss, T Freiwald, R McGregor, B Yan, L Wang, E Nova-Lamperti, ... Nature immunology 23 (1), 62-74, 2022 | 146 | 2022 |
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells E Perucha, R Melchiotti, JA Bibby, W Wu, KS Frederiksen, CA Roberts, ... Nature communications 10 (1), 498, 2019 | 111 | 2019 |
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation N Niyonzima, J Rahman, N Kunz, EE West, T Freiwald, JV Desai, ... Science immunology 6 (66), eabf2489, 2021 | 59 | 2021 |
Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate JA Bibby, HA Purvis, T Hayday, A Chandra, K Okkenhaug, S Rosenzweig, ... Nature communications 11 (1), 3412, 2020 | 59 | 2020 |
Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus KR Bashant, AM Aponte, D Randazzo, PR Sangsari, AJT Wood, JA Bibby, ... Annals of the rheumatic diseases 80 (2), 209-218, 2021 | 51 | 2021 |
SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyperactivation B Yan, T Freiwald, D Chauss, L Wang, E West, J Bibby, M Olson, ... Research Square, 2020 | 32 | 2020 |
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19 R McGregor, D Chauss, T Freiwald, B Yan, L Wang, E Nova-Lamperti, ... BioRxiv, 2020.07. 18.210161, 2020 | 26 | 2020 |
Systematic single-cell pathway analysis to characterize early T cell activation JA Bibby, D Agarwal, T Freiwald, N Kunz, NS Merle, EE West, P Singh, ... Cell reports 41 (8), 2022 | 24 | 2022 |
Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells F Clarke, CK Jordan, E Gutierrez-Martinez, JA Bibby, C Sanchez-Blanco, ... PLoS One 12 (10), e0186625, 2017 | 16 | 2017 |
Multi-color molecular visualization of signaling proteins reveals how C-terminal Src kinase nanoclusters regulate T cell receptor activation S Simoncelli, J Griffié, DJ Williamson, J Bibby, C Bray, R Zamoyska, ... Cell Reports 33 (12), 2020 | 15 | 2020 |
The immunogenicity of fractional intradermal doses of the inactivated poliovirus vaccine is associated with the size of the intradermal fluid bleb J Bibby, Y Saidu, A Umesi, N Moneke-Anyanwoke, AO Bashorun, ... Clinical Infectious Diseases 65 (5), 851-854, 2017 | 8 | 2017 |
Phosphatase PTPN22 regulates dendritic cell homeostasis and cdc2 dependent T cell responses HA Purvis, F Clarke, AB Montgomery, C Colas, JA Bibby, GH Cornish, ... Frontiers in immunology 11, 376, 2020 | 7 | 2020 |
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection EE West, NS Merle, MM Kamiński, G Palacios, D Kumar, L Wang, ... Immunity 56 (9), 2036-2053. e12, 2023 | 6 | 2023 |
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Sci Immunol 6: eabg0833 B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli, CJ Zhang, ... | 5 | 2021 |
Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation JA Bibby, D Agarwal, T Freiwald, N Kunz, NS Merle, EE West, ... BioRxiv, 2022.02. 07.478807, 2022 | 2 | 2022 |
Multi-colour DNA-qPAINT reveals how Csk nano-clusters regulate T-cell receptor signalling S Simoncelli, J Griffié, DJ Williamson, J Bibby, C Bray, R Zamoyska, ... bioRxiv, 857516, 2019 | 2 | 2019 |
Cholesterol metabolism drives regulatory B cell function JA Bibby, HA Purvis, T Hayday, A Chandra, K Okkenhaug, M Wood, ... bioRxiv, 2020.01. 03.893982, 2020 | 1 | 2020 |
SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyper-activation (preprint) B Yan, T Freiwald, D Chauss, L Wang, E West, J Bibby, M Olson, ... | 1 | 2020 |
183 Exploring the role of C5aR2 in neutrophil-driven autoimmune diseases: An often overlooked player in the pathogenesis of epidermolysis bullosa acquisita D Seiler, M Kleingarn, K Kähler, T Freiwald, J Bibby, C Gruner, ... Immunobiology 228 (5), 152633, 2023 | | 2023 |