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Steven Estus
Steven Estus
Verified email at email.uky.edu
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Production of the Alzheimer amyloid β protein by normal proteolytic processing
M Shoji, TE Golde, J Ghiso, TT Cheung, S Estus, LM Shaffer, XD Cai, ...
Science 258 (5079), 126-129, 1992
19741992
Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis.
S Estus, WJ Zaks, RS Freeman, M Gruda, R Bravo, EM Johnson Jr
The Journal of cell biology 127 (6), 1717-1727, 1994
10841994
Processing of the amyloid protein precursor to potentially amyloidogenic derivatives
TE Golde, S Estus, LH Younkin, DJ Selkoe, SG Younkin
Science 255 (5045), 728-730, 1992
9561992
Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death
RS Freeman, S Estus, EM Johnson Jr
Neuron 12 (2), 343-355, 1994
7451994
Expression of β amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR
TE Golde, S Estus, M Usiak, LH Younkin, SG Younkin
Neuron 4 (2), 253-267, 1990
5411990
Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor
S Estus, TE Golde, T Kunishita, D Blades, D Lowery, M Eisen, M Usiak, ...
Science 255 (5045), 726-728, 1992
5301992
The plasmin system is induced by and degrades amyloid-β aggregates
HM Tucker, M Kihiko, JN Caldwell, S Wright, T Kawarabayashi, D Price, ...
Journal of Neuroscience 20 (11), 3937-3946, 2000
3912000
Aggregated amyloid-β protein induces cortical neuronal apoptosis and concomitant “apoptotic” pattern of gene induction
S Estus, HM Tucker, C van Rooyen, S Wright, EF Brigham, M Wogulis, ...
Journal of Neuroscience 17 (20), 7736-7745, 1997
3471997
NADPH oxidase contributes directly to oxidative stress and apoptosis in nerve growth factor-deprived sympathetic neurons
SP Tammariello, MT Quinn, S Estus
The Journal of Neuroscience 20 (1), RC53, 2000
2922000
CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing
M Malik, JF Simpson, I Parikh, BR Wilfred, DW Fardo, PT Nelson, S Estus
Journal of Neuroscience 33 (33), 13320-13325, 2013
2862013
APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease
KL Youmans, LM Tai, E Nwabuisi-Heath, L Jungbauer, T Kanekiyo, ...
Journal of Biological Chemistry 287 (50), 41774-41786, 2012
2802012
Adriamycin-induced, TNF-α-mediated central nervous system toxicity
J Tangpong, MP Cole, R Sultana, G Joshi, S Estus, M Vore, WS Clair, ...
Neurobiology of disease 23 (1), 127-139, 2006
2672006
Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain
G Joshi, R Sultana, J Tangpong, MP Cole, DK St Clair, M Vore, S Estus, ...
Free radical research 39 (11), 1147-1154, 2005
2292005
Adriamycin‐mediated nitration of manganese superoxide dismutase in the central nervous system: insight into the mechanism of chemobrain
J Tangpong, MP Cole, R Sultana, S Estus, M Vore, W St. Clair, ...
Journal of neurochemistry 100 (1), 191-201, 2007
2092007
Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer’s disease
CC Liu, CW Tsai, F Deak, J Rogers, M Penuliar, YM Sung, JN Maher, ...
Neuron 84 (1), 63-77, 2014
1952014
The expression of key oxidative stress-handling genes in different brain regions in Alzheimer’s disease
MY Aksenov, HM Tucker, P Nair, MV Aksenova, DA Butterfield, S Estus, ...
Journal of Molecular Neuroscience 11, 151-164, 1998
1851998
Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased with APOE4 and Alzheimer Disease in a Transgenic Mouse Model and Human Samples …
LM Tai, T Bilousova, L Jungbauer, SK Roeske, KL Youmans, C Yu, ...
Journal of Biological Chemistry 288 (8), 5914-5926, 2013
1812013
Insulysin hydrolyzes amyloid β peptides to products that are neither neurotoxic nor deposit on amyloid plaques
A Mukherjee, E Song, M Kihiko-Ehmann, JP Goodman, JS Pyrek, S Estus, ...
Journal of Neuroscience 20 (23), 8745-8749, 2000
1782000
Genetics ignite focus on microglial inflammation in Alzheimer’s disease
M Malik, I Parikh, JB Vasquez, C Smith, L Tai, G Bu, MJ LaDu, DW Fardo, ...
Molecular neurodegeneration 10, 1-12, 2015
1682015
Neuroprotective action of cycloheximide involves induction of Bcl-2 and antioxidant pathways
K Furukawa, S Estus, W Fu, RJ Mark, MP Mattson
The Journal of cell biology 136 (5), 1137-1149, 1997
1641997
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