| HIV-1 reverse transcriptase still remains a new drug target: structure, function, classical inhibitors, and new inhibitors with innovative mechanisms of actions F Esposito, A Corona, E Tramontano Molecular biology international 2012, 2012 | 159 | 2012 |
| Identification of inhibitors of SARS-CoV-2 3CL-pro enzymatic activity using a small molecule in vitro repurposing screen M Kuzikov, E Costanzi, J Reinshagen, F Esposito, L Vangeel, M Wolf, ... ACS pharmacology & translational science 4 (3), 1096-1110, 2021 | 110 | 2021 |
| Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H … F Esposito, C Sanna, C Del Vecchio, V Cannas, A Venditti, A Corona, ... Pathogens and disease 68 (3), 116-124, 2013 | 90 | 2013 |
| Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication F Esposito, I Carli, C Del Vecchio, L Xu, A Corona, N Grandi, D Piano, ... Phytomedicine 23 (12), 1383-1391, 2016 | 87 | 2016 |
| Structure–activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain G Cuzzucoli Crucitti, M Métifiot, L Pescatori, A Messore, VN Madia, ... Journal of medicinal chemistry 58 (4), 1915-1928, 2015 | 85 | 2015 |
| From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors L Xu, N Grandi, C Del Vecchio, D Mandas, A Corona, D Piano, F Esposito, ... Journal of microbiology 53, 288-293, 2015 | 80 | 2015 |
| Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by diketo acid derivatives A Corona, FS Di Leva, S Thierry, L Pescatori, G Cuzzucoli Crucitti, ... Antimicrobial agents and chemotherapy 58 (10), 6101-6110, 2014 | 77 | 2014 |
| Basic quinolinonyl diketo acid derivatives as inhibitors of HIV integrase and their activity against RNase H function of reverse transcriptase R Costi, M Métifiot, S Chung, G Cuzzucoli Crucitti, K Maddali, L Pescatori, ... Journal of Medicinal Chemistry 57 (8), 3223-3234, 2014 | 66 | 2014 |
| A new vinyl selenone-based domino approach to spirocyclopropyl oxindoles endowed with anti-HIV RT activity M Palomba, L Rossi, L Sancineto, E Tramontano, A Corona, L Bagnoli, ... Organic & biomolecular chemistry 14 (6), 2015-2024, 2016 | 62 | 2016 |
| Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase R Meleddu, S Distinto, A Corona, E Tramontano, G Bianco, C Melis, ... Journal of enzyme inhibition and medicinal chemistry 32 (1), 130-136, 2017 | 60 | 2017 |
| (3Z)-3-(2-[4-(aryl)-1, 3-thiazol-2-yl] hydrazin-1-ylidene)-2, 3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase R Meleddu, S Distinto, A Corona, G Bianco, V Cannas, F Esposito, ... European journal of medicinal chemistry 93, 452-460, 2015 | 59 | 2015 |
| Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase A Corona, T Masaoka, G Tocco, E Tramontano, SFJ Le Grice Future medicinal chemistry 5 (18), 2127-2139, 2013 | 59 | 2013 |
| Antityrosinase activity of Euphorbia characias extracts F Pintus, D Spano, A Corona, R Medda PeerJ 3, e1305, 2015 | 58 | 2015 |
| Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase VP Sonar, A Corona, S Distinto, E Maccioni, R Meleddu, B Fois, C Floris, ... European journal of medicinal chemistry 130, 248-260, 2017 | 56 | 2017 |
| Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC6 A Corona, R Meleddu, F Esposito, S Distinto, G Bianco, T Masaoka, ... PloS one 11 (1), e0147225, 2016 | 55 | 2016 |
| Ribonuclease H, an unexploited target for antiviral intervention against HIV and hepatitis B virus E Tramontano, A Corona, L Menendez-Arias Antiviral research 171, 104613, 2019 | 52 | 2019 |
| Molecular aspects of the RT/drug interactions. Perspective of dual inhibitors S Distinto, E Maccioni, R Meleddu, A Corona, S Alcaro, E Tramontano Current pharmaceutical design 19 (10), 1850-1859, 2013 | 50 | 2013 |
| Quercetin blocks Ebola virus infection by counteracting the VP24 interferon-inhibitory function E Fanunza, M Iampietro, S Distinto, A Corona, M Quartu, E Maccioni, ... Antimicrobial agents and chemotherapy 64 (7), 10.1128/aac. 00530-20, 2020 | 47 | 2020 |
| Biological activities of aerial parts extracts of Euphorbia characias MB Pisano, S Cosentino, S Viale, D Spanò, A Corona, F Esposito, ... BioMed research international 2016, 2016 | 47 | 2016 |
| Alizarine derivatives as new dual inhibitors of the HIV‐1 reverse transcriptase‐associated DNA polymerase and RNase H activities effective also on the RNase H activity of non … F Esposito, T Kharlamova, S Distinto, L Zinzula, YC Cheng, G Dutschman, ... The FEBS journal 278 (9), 1444-1457, 2011 | 47 | 2011 |
Enzo TramontanoProfessore Ordinario di Microbiologia, Dipartimento di Scienze della Vita e dell'Ambiente, Università di CagliariVerified email at unica.it
