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Stephanie Schorge
Stephanie Schorge
Professor of Neuroscience, UCL
Email verificata su ucl.ac.uk - Home page
Titolo
Citata da
Citata da
Anno
Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin
SK Tate, C Depondt, SM Sisodiya, GL Cavalleri, S Schorge, N Soranzo, ...
Proceedings of the National Academy of Sciences 102 (15), 5507-5512, 2005
4032005
Studies of NMDA receptor function and stoichiometry with truncated and tandem subunits
S Schorge, D Colquhoun
Journal of Neuroscience 23 (4), 1151-1158, 2003
3502003
Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy
RC Wykes, JH Heeroma, L Mantoan, K Zheng, DC MacDonald, ...
Science translational medicine 4 (161), 161ra152-161ra152, 2012
2852012
Identification of functionally distinct isoforms of the N-type Ca 2+ channel in rat sympathetic ganglia and brain
DL Zhixin Lin, Stephanie Haus, Jeremy Edgerton
Neuron 18 (1), 153-166, 1997
2371997
MicroRNAs in epilepsy: pathophysiology and clinical utility
DC Henshall, HM Hamer, RJ Pasterkamp, DB Goldstein, J Kjems, ...
The Lancet Neurology 15 (13), 1368-1376, 2016
2262016
Voltage sensor charge loss accounts for most cases of hypokalemic periodic paralysis
E Matthews, R Labrum, MG Sweeney, R Sud, A Haworth, PF Chinnery, ...
Neurology 72 (18), 1544-1547, 2009
2262009
dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice
G Colasante, G Lignani, S Brusco, C Di Berardino, J Carpenter, ...
Molecular Therapy 28 (1), 235-253, 2020
1672020
Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures
T Stödberg, A McTague, AJ Ruiz, H Hirata, J Zhen, P Long, I Farabella, ...
Nature communications 6 (1), 8038, 2015
1582015
Chemical–genetic attenuation of focal neocortical seizures
D Kätzel, E Nicholson, S Schorge, MC Walker, DM Kullmann
Nature communications 5 (1), 3847, 2014
1482014
Chloride channel myotonia: exon 8 hot-spot for dominant-negative interactions
D Fialho, S Schorge, U Pucovska, NP Davies, R Labrum, A Haworth, ...
Brain 130 (12), 3265-3274, 2007
1382007
Alternative splicing of a short cassette exon in α1B generates functionally distinct N-type calcium channels in central and peripheral neurons
Z Lin, Y Lin, S Schorge, JQ Pan, M Beierlein, D Lipscombe
Journal of Neuroscience 19 (13), 5322-5331, 1999
1241999
Episodic ataxia type 1: a neuronal potassium channelopathy
S Rajakulendran, S Schorge, DM Kullmann, MG Hanna
Neurotherapeutics 4, 258-266, 2007
1172007
Genetic and functional characterisation of the P/Q calcium channel in episodic ataxia with epilepsy
S Rajakulendran, TD Graves, RW Labrum, D Kotzadimitriou, L Eunson, ...
The Journal of physiology 588 (11), 1905-1913, 2010
1032010
Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits
S Schorge, S Elenes, D Colquhoun
The Journal of physiology 569 (2), 395-418, 2005
1012005
Human ataxias: a genetic dissection of inositol triphosphate receptor (ITPR1)-dependent signaling
S Schorge, J van de Leemput, A Singleton, H Houlden, J Hardy
Trends in neurosciences 33 (5), 211-219, 2010
912010
Gene therapy in epilepsy—is it time for clinical trials?
DM Kullmann, S Schorge, MC Walker, RC Wykes
Nature Reviews Neurology 10 (5), 300-304, 2014
882014
Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study
P May, S Girard, M Harrer, DR Bobbili, J Schubert, S Wolking, F Becker, ...
The Lancet Neurology 17 (8), 699-708, 2018
872018
Potent anti-seizure effects of locked nucleic acid antagomirs targeting miR-134 in multiple mouse and rat models of epilepsy
CR Reschke, LFA Silva, BA Norwood, K Senthilkumar, G Morris, ...
Molecular Therapy-Nucleic Acids 6, 45-56, 2017
872017
Epilepsy gene therapy using an engineered potassium channel
A Snowball, E Chabrol, RC Wykes, T Shekh-Ahmad, JH Cornford, A Lieb, ...
Journal of neuroscience 39 (16), 3159-3169, 2019
832019
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy
G Colasante, Y Qiu, L Massimino, C Di Berardino, JH Cornford, ...
Brain 143 (3), 891-905, 2020
812020
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