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Robin Mathew, Ph.D.
Robin Mathew, Ph.D.
Therapeutic Area Strategy Lead, Global Clinical Development
Verified email at umdnj.edu
Title
Cited by
Cited by
Year
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
K Degenhardt, R Mathew, B Beaudoin, K Bray, D Anderson, G Chen, ...
Cancer cell 10 (1), 51-64, 2006
24102006
Role of autophagy in cancer
R Mathew, V Karantza-Wadsworth, E White
Nature Reviews Cancer 7 (12), 961-967, 2007
21922007
Autophagy suppresses tumorigenesis through elimination of p62
R Mathew, CM Karp, B Beaudoin, N Vuong, G Chen, HY Chen, K Bray, ...
Cell 137 (6), 1062-1075, 2009
19562009
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
JY Guo, HY Chen, R Mathew, J Fan, AM Strohecker, G Karsli-Uzunbas, ...
Genes & development 25 (5), 460-470, 2011
14282011
Autophagy suppresses tumor progression by limiting chromosomal instability
R Mathew, S Kongara, B Beaudoin, CM Karp, K Bray, K Degenhardt, ...
Genes & development 21 (11), 1367-1381, 2007
11102007
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
V Karantza-Wadsworth, S Patel, O Kravchuk, G Chen, R Mathew, S Jin, ...
Genes & development 21 (13), 1621-1635, 2007
9942007
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
JJ Kamphorst, JR Cross, J Fan, E De Stanchina, R Mathew, EP White, ...
Proceedings of the National Academy of Sciences 110 (22), 8882-8887, 2013
6792013
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
JY Guo, G Karsli-Uzunbas, R Mathew, SC Aisner, JJ Kamphorst, ...
Genes & development 27 (13), 1447-1461, 2013
5982013
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E–Driven Lung Tumors
AM Strohecker, JY Guo, G Karsli-Uzunbas, SM Price, GJ Chen, R Mathew, ...
Cancer discovery 3 (11), 1272-1285, 2013
4562013
Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
J Fan, JJ Kamphorst, R Mathew, MK Chung, E White, T Shlomi, ...
Molecular systems biology 9 (1), 712, 2013
4472013
Role of autophagy in suppression of inflammation and cancer
E White, C Karp, AM Strohecker, Y Guo, R Mathew
Current opinion in cell biology 22 (2), 212-217, 2010
3592010
Metabolic catastrophe as a means to cancer cell death
S Jin, RS DiPaola, R Mathew, E White
Journal of cell science 120 (3), 379-383, 2007
3052007
Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
R Mathew, E White
Current opinion in genetics & development 21 (1), 113-119, 2011
2802011
NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition
T Shimazu, K Degenhardt, A Nur-E-Kamal, J Zhang, T Yoshida, Y Zhang, ...
Genes & development 21 (8), 929-941, 2007
1662007
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition
K Bray, R Mathew, A Lau, JJ Kamphorst, J Fan, J Chen, HY Chen, ...
PloS one 7 (7), e41831, 2012
1612012
Role of the polarity determinant crumbs in suppressing mammalian epithelial tumor progression
CM Karp, TT Tan, R Mathew, D Nelson, C Mukherjee, K Degenhardt, ...
Cancer research 68 (11), 4105-4115, 2008
1392008
Autophagy, stress, and cancer metabolism: what doesn't kill you makes you stronger
R Mathew, E White
Cold Spring Harbor symposia on quantitative biology 76, 389-396, 2011
1382011
Functional role of autophagy-mediated proteome remodeling in cell survival signaling and innate immunity
R Mathew, S Khor, SR Hackett, JD Rabinowitz, DH Perlman, E White
Molecular cell 55 (6), 916-930, 2014
1212014
Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapy
RS DiPaola, D Dvorzhinski, A Thalasila, V Garikapaty, D Doram, M May, ...
The Prostate 68 (16), 1743-1752, 2008
1182008
Alterations in p53 and pRb pathways and their prognostic significance in oesophageal cancer
R Mathew, S Arora, R Khanna, M Mathur, NK Shukla, R Ralhan
European Journal of cancer 38 (6), 832-841, 2002
782002
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Articles 1–20