| Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane F Hong, ML Freeman, DC Liebler Chemical research in toxicology 18 (12), 1917-1926, 2005 | 460 | 2005 |
| Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression S Biswas, M Guix, C Rinehart, TC Dugger, A Chytil, HL Moses, ... The Journal of clinical investigation 117 (5), 1305-1313, 2007 | 407 | 2007 |
| Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation F Hong, KR Sekhar, ML Freeman, DC Liebler Journal of Biological Chemistry 280 (36), 31768-31775, 2005 | 383 | 2005 |
| Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo NJ Brown, S Nakamura, L Ma, I Nakamura, E Donnert, M Freeman, ... Kidney international 58 (3), 1219-1227, 2000 | 360 | 2000 |
| Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3 L Gao, J Wang, KR Sekhar, H Yin, NF Yared, SN Schneider, S Sasi, ... Journal of Biological Chemistry 282 (4), 2529-2537, 2007 | 353 | 2007 |
| Age-related retinopathy in NRF2-deficient mice Z Zhao, Y Chen, J Wang, P Sternberg, ML Freeman, HE Grossniklaus, ... PloS one 6 (4), e19456, 2011 | 339 | 2011 |
| Cell biology of hyperthermia and radiation WC Dewey, DP Highfield, ML Freeman, RA Coss, RSL Wong Proceedings of the 6th international congress of radiation research, 1979 | 310 | 1979 |
| Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition T Oikawa, M Freeman, W Lo, DE Vaughan, A Fogo Kidney international 51 (1), 164-172, 1997 | 303 | 1997 |
| Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells DW Abbott, JT Holt, ML Freeman Journal of the National Cancer Institute 90 (13), 978-985, 1998 | 280 | 1998 |
| Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2 J Pi, Y Bai, JM Reece, J Williams, D Liu, ML Freeman, WE Fahl, D Shugar, ... Free Radical Biology and Medicine 42 (12), 1797-1806, 2007 | 249 | 2007 |
| Survivin as a therapeutic target for radiation sensitization in lung cancer B Lu, Y Mu, C Cao, F Zeng, S Schneider, J Tan, J Price, J Chen, ... Cancer research 64 (8), 2840-2845, 2004 | 248 | 2004 |
| Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3 G Rachakonda, Y Xiong, KR Sekhar, SL Stamer, DC Liebler, ML Freeman Chemical research in toxicology 21 (3), 705-710, 2008 | 239 | 2008 |
| Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling KW Kim, RW Mutter, C Cao, JM Albert, M Freeman, DE Hallahan, B Lu Journal of Biological Chemistry 281 (48), 36883-36890, 2006 | 225 | 2006 |
| NADPH oxidase limits innate immune responses in the lungs in mice BH Segal, W Han, JJ Bushey, M Joo, Z Bhatti, J Feminella, CG Dennis, ... PloS one 5 (3), e9631, 2010 | 202 | 2010 |
| Cysteine-based regulation of the CUL3 adaptor protein Keap1 KR Sekhar, G Rachakonda, ML Freeman Toxicology and applied pharmacology 244 (1), 21-26, 2010 | 192 | 2010 |
| Increased expression of nuclear factor E2 p45‐related factor 2 (NRF2) in head and neck squamous cell carcinomas DR Stacy, K Ely, PP Massion, WG Yarbrough, DE Hallahan, KR Sekhar, ... Head & Neck: Journal for the Sciences and Specialties of the Head and Neck …, 2006 | 169 | 2006 |
| Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2 KR Sekhar, XX Yan, ML Freeman Oncogene 21 (44), 6829-6834, 2002 | 169 | 2002 |
| Proteins containing non‐native disulfide bonds generated by oxidative stress can act as signals for the induction of the heat shock response AT McDuffee, G Senisterra, S Huntley, JR Lepock, KR Sekhar, ... Journal of cellular physiology 171 (2), 143-151, 1997 | 157 | 1997 |
| Multi‐faceted regulation of γ‐glutamylcysteine synthetase SR Soltaninassab, KR Sekhar, MJ Meredith, ML Freeman Journal of cellular physiology 182 (2), 163-170, 2000 | 143 | 2000 |
| Smad3–ATF3 signaling mediates TGF-β suppression of genes encoding Phase II detoxifying proteins AV Bakin, NV Stourman, KR Sekhar, C Rinehart, X Yan, MJ Meredith, ... Free Radical Biology and Medicine 38 (3), 375-387, 2005 | 135 | 2005 |
