| Large-scale structural analysis of the classical human protein tyrosine phosphatome AJ Barr, E Ugochukwu, WH Lee, ONF King, P Filippakopoulos, I Alfano, ... Cell 136 (2), 352-363, 2009 | 543 | 2009 |
| Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study NA Burgess-Brown, S Sharma, F Sobott, C Loenarz, U Oppermann, ... Protein expression and purification 59 (1), 94-102, 2008 | 450 | 2008 |
| High-throughput production of human proteins for crystallization: the SGC experience P Savitsky, J Bray, CDO Cooper, BD Marsden, P Mahajan, ... Journal of structural biology 172 (1), 3-13, 2010 | 343 | 2010 |
| Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison M Ainsworth, M Andersson, K Auckland, JK Baillie, E Barnes, S Beer, ... The Lancet Infectious Diseases 20 (12), 1390-1400, 2020 | 316 | 2020 |
| K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac YY Dong, ACW Pike, A Mackenzie, C McClenaghan, P Aryal, L Dong, ... Science 347 (6227), 1256-1259, 2015 | 313 | 2015 |
| Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ... Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013 | 277 | 2013 |
| Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2) M Grieben, ACW Pike, CA Shintre, E Venturi, S El-Ajouz, A Tessitore, ... Nature structural & molecular biology 24 (2), 114-122, 2017 | 190 | 2017 |
| Structural analysis of human KDM5B guides histone demethylase inhibitor development C Johansson, S Velupillai, A Tumber, A Szykowska, ES Hookway, ... Nature chemical biology 12 (7), 539-545, 2016 | 170 | 2016 |
| Human SNM1A and XPF–ERCC1 collaborate to initiate DNA interstrand cross-link repair AT Wang, B Sengerová, E Cattell, T Inagawa, JM Hartley, K Kiakos, ... Genes & development 25 (17), 1859-1870, 2011 | 169 | 2011 |
| Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ... Journal of medicinal chemistry 55 (14), 6639-6643, 2012 | 159 | 2012 |
| Structure of the human RECQ1 helicase reveals a putative strand-separation pin ACW Pike, B Shrestha, V Popuri, N Burgess-Brown, L Muzzolini, ... Proceedings of the National Academy of Sciences 106 (4), 1039-1044, 2009 | 135 | 2009 |
| The structural basis of ZMPSTE24-dependent laminopathies A Quigley, YY Dong, ACW Pike, L Dong, L Shrestha, G Berridge, ... Science 339 (6127), 1604-1607, 2013 | 125 | 2013 |
| The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K SR Bushell, ACW Pike, ME Falzone, NJG Rorsman, CM Ta, RA Corey, ... Nature communications 10 (1), 3956, 2019 | 124 | 2019 |
| Potent and selective KDM5 inhibitor stops cellular demethylation of H3K4me3 at transcription start sites and proliferation of MM1S myeloma cells A Tumber, A Nuzzi, ES Hookway, SB Hatch, S Velupillai, C Johansson, ... Cell chemical biology 24 (3), 371-380, 2017 | 119 | 2017 |
| High throughput production of recombinant human proteins for crystallography O Gileadi, NA Burgess-Brown, SM Colebrook, G Berridge, P Savitsky, ... Structural proteomics: high-throughput methods, 221-246, 2008 | 100 | 2008 |
| 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors V Bavetsias, RM Lanigan, GF Ruda, B Atrash, MG McLaughlin, A Tumber, ... Journal of medicinal chemistry 59 (4), 1388-1409, 2016 | 99 | 2016 |
| Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching M Philpott, CM Rogers, C Yapp, C Wells, JP Lambert, C Strain-Damerell, ... Epigenetics & chromatin 7, 1-12, 2014 | 97 | 2014 |
| The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4 AA Watson, P Mahajan, HDT Mertens, MJ Deery, W Zhang, P Pham, X Du, ... Journal of molecular biology 422 (1), 3-17, 2012 | 90 | 2012 |
| Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis AB Montgomery, J Kopec, L Shrestha, ML Thezenas, NA Burgess-Brown, ... Annals of the rheumatic diseases 75 (6), 1255-1261, 2016 | 87 | 2016 |
| Beyond just peptide antigens: the complex world of peptide-based cancer vaccines AJ Stephens, NA Burgess-Brown, S Jiang Frontiers in Immunology 12, 696791, 2021 | 76 | 2021 |
