| Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell … E Mössner, P Brünker, S Moser, U Püntener, C Schmidt, S Herter, R Grau, ... Blood, The Journal of the American Society of Hematology 115 (22), 4393-4402, 2010 | 1049 | 2010 |
| The 3.2-Å crystal structure of the human IgG1 Fc fragment–FcγRIII complex P Sondermann, R Huber, V Oosthuizen, U Jacob Nature 406 (6793), 267-273, 2000 | 997 | 2000 |
| Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose C Ferrara, S Grau, C Jäger, P Sondermann, P Brünker, I Waldhauer, ... Proceedings of the National Academy of Sciences 108 (31), 12669-12674, 2011 | 894 | 2011 |
| Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity S Krapp, Y Mimura, R Jefferis, R Huber, P Sondermann Journal of molecular biology 325 (5), 979-989, 2003 | 806 | 2003 |
| Mechanisms of autoantibody-induced pathology RJ Ludwig, K Vanhoorelbeke, F Leypoldt, Z Kaya, K Bieber, ... Frontiers in immunology 8, 603, 2017 | 447 | 2017 |
| The carbohydrate at FcγRIIIa Asn-162: an element required for high affinity binding to non-fucosylated IgG glycoforms C Ferrara, F Stuart, P Sondermann, P Brünker, P Umaña Journal of Biological Chemistry 281 (8), 5032-5036, 2006 | 444 | 2006 |
| Role of oligosaccharide residues of IgG1-Fc in FcγRIIb binding Y Mimura, P Sondermann, R Ghirlando, J Lund, SP Young, M Goodall, ... Journal of Biological Chemistry 276 (49), 45539-45547, 2001 | 383 | 2001 |
| General mechanism for modulating immunoglobulin effector function P Sondermann, A Pincetic, J Maamary, K Lammens, JV Ravetch Proceedings of the National Academy of Sciences 110 (24), 9868-9872, 2013 | 257 | 2013 |
| Crystal structure of the soluble form of the human Fcγ‐receptor IIb: a new member of the immunoglobulin superfamily at 1.7 Å resolution P Sondermann, R Huber, U Jacob The EMBO journal, 1999 | 237 | 1999 |
| Molecular basis for immune complex recognition: a comparison of Fc-receptor structures P Sondermann, J Kaiser, U Jacob Journal of molecular biology 309 (3), 737-749, 2001 | 229 | 2001 |
| The human low affinity Fcγ receptors IIa, IIb, and III bind IgG with fast kinetics and distinct thermodynamic properties K Maenaka, PA Van der Merwe, DI Stuart, EY Jones, P Sondermann Journal of Biological Chemistry 276 (48), 44898-44904, 2001 | 226 | 2001 |
| Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG K Wenig, L Chatwell, U von Pawel-Rammingen, L Björck, R Huber, ... Proceedings of the National Academy of Sciences 101 (50), 17371-17376, 2004 | 178 | 2004 |
| Kinetics and inhibition of recombinant human cystathionine γ-lyase: Toward the rational control of transsulfuration C Steegborn, T Clausen, P Sondermann, U Jacob, M Worbs, S Marinkovic, ... Journal of Biological Chemistry 274 (18), 12675-12684, 1999 | 139 | 1999 |
| Antigen binding molecules having modified Fc regions and altered binding to Fc receptors P Sondermann, CF Koller, P Brunker, F Stuart, P Umana | 104 | 2007 |
| Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex KS Wendt, HC Vodermaier, U Jacob, C Gieffers, M Gmachl, JM Peters, ... Nature structural biology 8 (9), 784-788, 2001 | 101 | 2001 |
| Crystals of the urokinase type plasminogen activator variant βc-uPA in complex with small molecule inhibitors open the way towards structure-based drug design E Zeslawska, A Schweinitz, A Karcher, P Sondermann, S Sperl, ... Journal of molecular biology 301 (2), 465-475, 2000 | 91 | 2000 |
| Human Fc gamma Receptor IIb Expressed in Escherichia coli Reveals IgG Binding Capability P Sondermann, U Jacob Biological chemistry 380 (6), 717-721, 1999 | 91 | 1999 |
| Harnessing Fc receptor biology in the design of therapeutic antibodies P Sondermann, DE Szymkowski Current opinion in immunology 40, 78-87, 2016 | 73 | 2016 |
| Novel 3rd Generation Humanized Type II CD20 Antibody with Glycoengineered Fc and Modified Elbow Hinge for Enhanced ADCC and Superior Apoptosis Induction. P Umana, E Moessner, P Bruenker, G Unsin, U Puentener, T Suter, ... Blood, The Journal of the American Society of Hematology 108 (11), 229-229, 2006 | 69 | 2006 |
| Epitope mapping of new monoclonal antibodies recognizing distinct human FcRII (CD32) isoforms V WEINRICH, P SONDERMANN, N BEWARDER, K WISSEL, J FREY Hybridoma 15 (2), 109-116, 1996 | 69 | 1996 |
