| New perspective for an old antidiabetic drug: metformin as anticancer agent A Leone, E Di Gennaro, F Bruzzese, A Avallone, A Budillon Advances in Nutrition and Cancer, 355-376, 2014 | 175 | 2014 |
| HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT F Bruzzese, A Leone, M Rocco, C Carbone, G Piro, M Caraglia, ... Journal of cellular physiology 226 (9), 2378-2390, 2011 | 155 | 2011 |
| Local and systemic protumorigenic effects of cancer-associated fibroblast-derived GDF15 F Bruzzese, C Hägglöf, A Leone, E Sjöberg, MS Roca, S Kiflemariam, ... Cancer research 74 (13), 3408-3417, 2014 | 136 | 2014 |
| Oxidative stress gene expression profile correlates with cancer patient poor prognosis: identification of crucial pathways might select novel therapeutic approaches A Leone, MS Roca, C Ciardiello, S Costantini, A Budillon Oxidative Medicine and Cellular Longevity 2017, 2017 | 118 | 2017 |
| Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation C Ciardiello, A Leone, P Lanuti, MS Roca, T Moccia, VR Minciacchi, ... Journal of Experimental & Clinical Cancer Research 38, 1-16, 2019 | 94 | 2019 |
| Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed E Di Gennaro, F Bruzzese, S Pepe, A Leone, P Delrio, P Subbarayan, ... Cancer biology & therapy 8 (9), 782-791, 2009 | 86 | 2009 |
| Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway A Leone, MS Roca, C Ciardiello, M Terranova-Barberio, C Vitagliano, ... Free Radical Biology and Medicine 89, 287-299, 2015 | 77 | 2015 |
| Endothelial progenitor cells, defined by the simultaneous surface expression of VEGFR 2 and CD 133, are not detectable in healthy peripheral and cord blood P Lanuti, G Rotta, C Almici, G Avvisati, A Budillon, P Doretto, N Malara, ... Cytometry Part A 89 (3), 259-270, 2016 | 71 | 2016 |
| Targeting autophagy in breast cancer S Cocco, A Leone, M Piezzo, R Caputo, V Di Lauro, F Di Rella, G Fusco, ... International journal of molecular sciences 21 (21), 7836, 2020 | 70 | 2020 |
| Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression M Terranova-Barberio, MS Roca, AI Zotti, A Leone, F Bruzzese, ... Oncotarget 7 (7), 7715, 2016 | 70 | 2016 |
| Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways F Bruzzese, B Pucci, MR Milone, C Ciardiello, R Franco, MI Chianese, ... Cell death & disease 4 (10), e878-e878, 2013 | 59 | 2013 |
| Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells MR Milone, B Pucci, F Bruzzese, C Carbone, G Piro, S Costantini, ... Cell death & disease 4 (5), e641-e641, 2013 | 58 | 2013 |
| Large extracellular vesicles: Size matters in tumor progression C Ciardiello, R Migliorino, A Leone, A Budillon Cytokine & Growth Factor Reviews 51, 69-74, 2020 | 57 | 2020 |
| Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial A Avallone, B Pecori, F Bianco, L Aloj, F Tatangelo, C Romano, V Granata, ... Oncotarget 6 (30), 30394, 2015 | 48 | 2015 |
| Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles A Russo, S Maiolino, V Pagliara, F Ungaro, F Tatangelo, A Leone, ... Oncotarget 7 (48), 79670, 2016 | 46 | 2016 |
| A standardized flow cytometry network study for the assessment of circulating endothelial cell physiological ranges P Lanuti, P Simeone, G Rotta, C Almici, G Avvisati, R Azzaro, G Bologna, ... Scientific Reports 8 (1), 5823, 2018 | 43 | 2018 |
| The crosstalk between cancer stem cells and microenvironment is critical for solid tumor progression: the significant contribution of extracellular vesicles C Ciardiello, A Leone, A Budillon Stem Cells International 2018, 2018 | 36 | 2018 |
| Occupational Therapy’s efficacy in children with Asperger’s syndrome: a systematic review of randomized controlled trials G Romagnoli, A Leone, J Sansoni, M Tofani, R De Santis, D Valente, ... La Clinica Terapeutica 170 (5), e382-e387, 2019 | 34 | 2019 |
| Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53 M Terranova-Barberio, B Pecori, MS Roca, S Imbimbo, F Bruzzese, ... Journal of Experimental & Clinical Cancer Research 36, 1-13, 2017 | 34 | 2017 |
| Management of non-small cell lung cancer in the era of personalized medicine G Rocco, A Morabito, A Leone, P Muto, F Fiore, A Budillon The international journal of biochemistry & cell biology 78, 173-179, 2016 | 33 | 2016 |
