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Joseph A. Liberman
Joseph A. Liberman
Postdoctoral Fellow, Department of Molecular, Cellular, and Developmental Biology, Yale University
Email verificata su yale.edu
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Citata da
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Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound …
KC Suddala, AJ Rinaldi, J Feng, AM Mustoe, CD Eichhorn, JA Liberman, ...
Nucleic acids research 41 (22), 10462-10475, 2013
1002013
Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold
JA Liberman, M Salim, J Krucinska, JE Wedekind
Nature chemical biology 9 (6), 353-355, 2013
952013
Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics
JA Liberman, KC Suddala, A Aytenfisu, D Chan, IA Belashov, M Salim, ...
Proceedings of the National Academy of Sciences 112 (27), E3485-E3494, 2015
762015
Riboswitch structure in the ligand‐free state
JA Liberman, JE Wedekind
Wiley Interdisciplinary Reviews: RNA 3 (3), 369-384, 2012
762012
T‐cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site
EA James, SD Van Haren, RA Ettinger, K Fijnvandraat, JA Liberman, ...
Journal of Thrombosis and Haemostasis 9 (4), 689-699, 2011
502011
A transition-state interaction shifts nucleobase ionization toward neutrality to facilitate small ribozyme catalysis
JA Liberman, M Guo, JL Jenkins, J Krucinska, Y Chen, PR Carey, ...
Journal of the American Chemical Society 134 (41), 16933-16936, 2012
302012
ITC analysis of ligand binding to preQ1 riboswitches
JA Liberman, JT Bogue, JL Jenkins, M Salim, JE Wedekind
Methods in enzymology 549, 435-450, 2014
282014
Molecular mechanism for preQ1-II riboswitch function revealed by molecular dynamics
AH Aytenfisu, JA Liberman, JE Wedekind, DH Mathews
Rna 21 (11), 1898-1907, 2015
252015
Crystallographic analysis of small ribozymes and riboswitches
GM Lippa, JA Liberman, JL Jenkins, J Krucinska, M Salim, JE Wedekind
Ribozymes, 159-184, 2012
242012
FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity
RA Ettinger, JA Liberman, D Gunasekera, K Puranik, EA James, ...
Blood advances 2 (4), 309-322, 2018
192018
Base ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world
JA Liberman, JE Wedekind
Current opinion in structural biology 21 (3), 327-334, 2011
162011
Wiley Interdiscip. Rev
JA Liberman, JE Wedekind
RNA 3 (3), 369-84, 2012
122012
Metal Dependence of Ligand Binding and Heavy-Atom Derivatization of Evolutionarily Distinct PreQ1 Riboswitches
JE Wedekind, JA Liberman, JL Jenkins, M Salim
Chemical Biology of Nucleic Acids, 423-440, 2014
22014
Sequence-modified factor VIII variants having reduced immunogenicity
RA Ettinger, MS Epstein, K Puranik, RJ Hughes, JA Liberman, E James, ...
Blood 120 (21), 2012
22012
Reduced Immunogenicity of FVIII Peptides by Rational Modifications of An Immunodominant T-Cell Epitope.
RA Ettinger, JA Liberman, DC Bolgiano, AR Thompson, KP Pratt
Blood, The Journal of the American Society of Hematology 114 (22), 220-220, 2009
22009
Translational control by diverse RNA folds that recognize the metabolite preQ (1)
J Liberman, M Salim, I Belashov, J Wedekind
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70, C1394-C1394, 2014
2014
Structural and functional analysis of gene regulatory preQ1 riboswitches
J Liberman
2014
MS93. O05
J Liberman, M Salim, I Belashov, J Wedekind
Acta Cryst 70, C1394, 2014
2014
Transition-state interactions that shift nucleobase ionization toward neutrality in the hairpin ribozyme
JE Wedekind, JA Liberman, M Guo, JL Jenkins, J Krucinska, Y Chen, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013
2013
Reduced immunogenicity of FVIII-C2 with F2196A modification of an immunodominant HLA-DRB1* 0101-restricted T-cell epitope
R ETTINGER, J LIBERMAN, A THOMPSON, K PRATT
Haemophilia 17 (3), 2011
2011
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20