| Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores X Liu, Z Zhang, J Ruan, Y Pan, VG Magupalli, H Wu, J Lieberman Nature 535 (7610), 153-158, 2016 | 2515 | 2016 |
| let-7 regulates self renewal and tumorigenicity of breast cancer cells F Yu, H Yao, P Zhu, X Zhang, Q Pan, C Gong, Y Huang, X Hu, F Su, ... Cell 131 (6), 1109-1123, 2007 | 2481 | 2007 |
| Identification of host proteins required for HIV infection through a functional genomic screen AL Brass, DM Dykxhoorn, Y Benita, N Yan, A Engelman, RJ Xavier, ... science 319 (5865), 921-926, 2008 | 1763 | 2008 |
| RNA interference targeting Fas protects mice from fulminant hepatitis E Song, SK Lee, J Wang, N Ince, N Ouyang, J Min, J Chen, P Shankar, ... Nature medicine 9 (3), 347-351, 2003 | 1673 | 2003 |
| Interfering with disease: a progress report on siRNA-based therapeutics A de Fougerolles, HP Vornlocher, J Maraganore, J Lieberman Nature reviews Drug discovery 6 (6), 443-453, 2007 | 1555 | 2007 |
| Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors E Song, P Zhu, SK Lee, D Chowdhury, S Kussman, DM Dykxhoorn, ... Nature biotechnology 23 (6), 709-717, 2005 | 1354 | 2005 |
| siRNA-directed inhibition of HIV-1 infection CD Novina, MF Murray, DM Dykxhoorn, PJ Beresford, J Riess, SK Lee, ... Nature medicine 8 (7), 681-686, 2002 | 1258 | 2002 |
| Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs Y Tay, L Kats, L Salmena, D Weiss, SM Tan, U Ala, F Karreth, L Poliseno, ... Cell 147 (2), 344-357, 2011 | 1087 | 2011 |
| The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal J Lieberman Nature Reviews Immunology 3 (5), 361-370, 2003 | 1077 | 2003 |
| Gasdermin E suppresses tumour growth by activating anti-tumour immunity Z Zhang, Y Zhang, S Xia, Q Kong, S Li, X Liu, C Junqueira, KF Meza-Sosa, ... Nature 579 (7799), 415-420, 2020 | 997 | 2020 |
| Knocking down disease: a progress report on siRNA therapeutics A Wittrup, J Lieberman Nature Reviews Genetics 16 (9), 543-552, 2015 | 923 | 2015 |
| Death by a thousand cuts: granzyme pathways of programmed cell death D Chowdhury, J Lieberman Annu. Rev. Immunol. 26, 389-420, 2008 | 819 | 2008 |
| Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus MA Lee-Kirsch, M Gong, D Chowdhury, L Senenko, K Engel, YA Lee, ... Nature genetics 39 (9), 1065-1067, 2007 | 734 | 2007 |
| γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair D Chowdhury, MC Keogh, H Ishii, CL Peterson, S Buratowski, ... Molecular cell 20 (5), 801-809, 2005 | 715 | 2005 |
| Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor Z Fan, PJ Beresford, DY Oh, D Zhang, J Lieberman Cell 112 (5), 659-672, 2003 | 713 | 2003 |
| miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to “seedless” 3′ UTR microRNA recognition elements A Lal, F Navarro, CA Maher, LE Maliszewski, N Yan, E O'Day, ... Molecular cell 35 (5), 610-625, 2009 | 687 | 2009 |
| Desperately seeking microRNA targets M Thomas, J Lieberman, A Lal Nature structural & molecular biology 17 (10), 1169-1174, 2010 | 634 | 2010 |
| FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ... Nature immunology 21 (7), 736-745, 2020 | 629 | 2020 |
| A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery MC Keogh, JA Kim, M Downey, J Fillingham, D Chowdhury, JC Harrison, ... Nature 439 (7075), 497-501, 2006 | 621 | 2006 |
| Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis D Martinvalet, P Zhu, J Lieberman Immunity 22 (3), 355-370, 2005 | 615 | 2005 |
