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William B. Parker
William B. Parker
PNP Therapeutics
Verified email at pnptherapeutics.com
Title
Cited by
Cited by
Year
Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer
WB Parker
Chemical reviews 109 (7), 2880-2893, 2009
6882009
Metabolism and mechanism of action of 5-fluorouracil
WB Parker, YC Cheng
Pharmacology & therapeutics 48 (3), 381-395, 1990
5861990
Metabolism and antiviral activity of ribavirin
WB Parker
Virus research 107 (2), 165-171, 2005
2842005
Effects of 2-Chloro-9-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)adenine on K562 Cellular Metabolism and the Inhibition of Human Ribonucleotide Reductase and …
WB Parker, SC Shaddix, CH Chang, EL White, LM Rose, RW Brockman, ...
Cancer research 51 (9), 2386-2394, 1991
2651991
Failure of cAMP agonists to activate rescued ΔF508 CFTR in CFBE41o airway epithelial monolayers
Z Bebok, JF Collawn, J Wakefield, W Parker, Y Li, K Varga, EJ Sorscher, ...
The Journal of physiology 569 (2), 601-615, 2005
2322005
Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines.
EJ Sorscher, S Peng, Z Bebok, PW Allan, LL Bennett Jr, WB Parker
Gene therapy 1 (4), 233-238, 1994
2271994
Interaction of 2-halogenated dATP analogs (F, Cl, and Br) with human DNA polymerases, DNA primase, and ribonucleotide reductase.
WB Parker, AR Bapat, JX Shen, AJ Townsend, YC Cheng
Molecular pharmacology 34 (4), 485-491, 1988
2021988
Mitochondrial toxicity of antiviral nucleoside analogs
WB Parker
Journal of NIH Research 6, 57-57, 1994
1791994
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3 …
WB Parker, EL White, SC Shaddix, LJ Ross, RW Buckheit Jr, JM Germany, ...
Journal of Biological Chemistry 266 (3), 1754-1762, 1991
1751991
Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies
JR Bertino, WR Waud, WB Parker, M Lubin
Cancer biology & therapy 11 (7), 627-632, 2011
1562011
In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase
WB Parker, SA King, PW Allan, LL Bennett Jr, JA Secrist III, ...
Human gene therapy 8 (14), 1637-1644, 1997
1461997
Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases
EL White, WB Parker, LJ Macy, SC Shaddix, G McCaleb, JA Secrist III, ...
Biochemical and biophysical research communications 161 (2), 393-398, 1989
1301989
Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells
WB Parker, PW Allan, SC Shaddix, LM Rose, HF Speegle, GY Gillespie, ...
Biochemical pharmacology 55 (10), 1673-1681, 1998
1231998
Purine nucleoside antimetabolites in development for the treatment of cancer.
WB Parker, JA Secrist 3rd, WR Waud
Current opinion in investigational drugs (London, England: 2000) 5 (6), 592-596, 2004
1172004
Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase
EM Bennett, C Li, PW Allan, WB Parker, SE Ealick
Journal of Biological Chemistry 278 (47), 47110-47118, 2003
1172003
Bystander Killing of Melanoma Cells Using the Human Tyrosinase Promoter to Express the Escherichia coli Purine Nucleoside Phosphorylase Gene
BW Hughes, AH Wells, Z Bebok, VK Gadi, RI Garver Jr, WB Parker, ...
Cancer research 55 (15), 3339-3345, 1995
1161995
Anti-AIDS agents, 1. Isolation and characterization of four new tetragalloylquinic acids as a new class of HIV reverse transcriptase inhibitors from tannic acid
M Nishizawa, T Yamagishi, GE Dutschman, WB Parker, AJ Bodner, ...
Journal of natural products 52 (4), 762-768, 1989
1151989
Lymphoma chemovirotherapy: CD20-targeted and convertase-armed measles virus can synergize with fludarabine
G Ungerechts, C Springfeld, ME Frenzke, J Lampe, PB Johnston, ...
Cancer research 67 (22), 10939-10947, 2007
1062007
An immunocompetent murine model for oncolysis with an armed and targeted measles virus
G Ungerechts, C Springfeld, ME Frenzke, J Lampe, WB Parker, ...
Molecular Therapy 15 (11), 1991-1997, 2007
1032007
Comparison of the mechanism of cytotoxicity of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl) adenine, 2-chloro-9-(2-deoxy-2-fluoro-β-D-ribofuranosyl) adenine, and 2-chloro …
WB Parker, SC Shaddix, LM Rose, DS Shewach, LW Hertel, JA Secrist, ...
Molecular pharmacology 55 (3), 515-520, 1999
981999
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