Evolution of minimal specificity and promiscuity in steroid hormone receptors GN Eick, JK Colucci, MJ Harms, EA Ortlund, JW Thornton PLoS genetics 8 (11), e1003072, 2012 | 139 | 2012 |
Ligand reduces galectin-1 sensitivity to oxidative inactivation by enhancing dimer formation SR Stowell, M Cho, CL Feasley, CM Arthur, X Song, JK Colucci, ... Journal of biological chemistry 284 (8), 4989-4999, 2009 | 108 | 2009 |
Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors MJ Harms, GN Eick, D Goswami, JK Colucci, PR Griffin, EA Ortlund, ... Proceedings of the National Academy of Sciences 110 (28), 11475-11480, 2013 | 79 | 2013 |
The effect of anticoagulants, temperature, and time on the human plasma metabolome and lipidome from healthy donors as determined by liquid chromatography-mass spectrometry M Khadka, A Todor, KM Maner-Smith, JK Colucci, VL Tran, DA Gaul, ... Biomolecules 9 (5), 200, 2019 | 37 | 2019 |
Structural analysis of the glucocorticoid receptor ligand-binding domain in complex with triamcinolone acetonide and a fragment of the atypical coregulator, small heterodimer … ER Weikum, CD Okafor, EH D’Agostino, JK Colucci, EA Ortlund Molecular pharmacology 92 (1), 12-21, 2017 | 22 | 2017 |
Delimiting the autoinhibitory module of von Willebrand factor W Deng, KM Voos, JK Colucci, ER Legan, EA Ortlund, P Lollar, R Li Journal of Thrombosis and Haemostasis 16 (10), 2097-2105, 2018 | 21 | 2018 |
X-ray crystal structure of the ancestral 3-ketosteroid receptor–progesterone–mifepristone complex shows mifepristone bound at the coactivator binding interface JK Colucci, EA Ortlund PLoS One 8 (11), e80761, 2013 | 13 | 2013 |
Alterations in the human plasma lipidome in response to tularemia vaccination KM Maner-Smith, JB Goll, M Khadka, TL Jensen, JK Colucci, CE Gelber, ... Vaccines 8 (3), 414, 2020 | 11 | 2020 |
Ligand-induced allosteric effects governing SR signaling CD Okafor, JK Colucci, EA Ortlund Nuclear Receptor Research 6, 1382, 2019 | 9 | 2019 |
Evolutionary tuning of a key helix drove androgen selectivity C Denise Okafor, JK Colucci, ML Cato, SH Khan, K Cottrill, D Hercules, ... bioRxiv, 2021.07. 21.453223, 2021 | 2 | 2021 |
Expression, purification and crystallization of the ancestral androgen receptor–DHT complex JK Colucci, EA Ortlund Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 2 | 2013 |
Evolution of Ligand Specificity in Steroid Hormone Nuclear Receptors J Colucci, E Ortlund Evolution 2, 6, 2012 | 1 | 2012 |
The allosteric mechanisms driving the evolution of androgen specificity C Okafor, J Colucci, E Ortlund ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Biophysical mechanisms driving the evolution of androgen specificity D Okafor, J Colucci, E Ortlund PROTEIN SCIENCE 25, 100-100, 2016 | | 2016 |
Historical mechanisms driving the evolution of ligand specificity in steroid hormone nuclear receptors JK Colucci Emory University, 2014 | | 2014 |
BEYOND MINIMAL SPECIFICITY: EVOLVING THE ABILITY TO DISCRIMINATE AMONG DIVERSE 3-KETOSTEROIDS JK Colucci, GN Eick, JW Thornton, EA Ortlund1e Distribution Agreement, 195, 0 | | |