| Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA A Bochkarev, RA Pfuetzner, AM Edwards, L Frappier Nature 385 (6612), 176-181, 1997 | 722 | 1997 |
| Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1: implications for EBV-mediated immortalization V Saridakis, Y Sheng, F Sarkari, MN Holowaty, K Shire, T Nguyen, ... Molecular cell 18 (1), 25-36, 2005 | 436 | 2005 |
| Molecular recognition of p53 and MDM2 by USP7/HAUSP Y Sheng, V Saridakis, F Sarkari, S Duan, T Wu, CH Arrowsmith, ... Nature structural & molecular biology 13 (3), 285-291, 2006 | 361 | 2006 |
| Human CD8+ T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)–containing protein requires exogenous processing N Blake, S Lee, I Redchenko, W Thomas, N Steven, A Leese, ... Immunity 7 (6), 791-802, 1997 | 325 | 1997 |
| Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA G Mer, A Bochkarev, R Gupta, E Bochkareva, L Frappier, CJ Ingles, ... Cell 103 (3), 449-456, 2000 | 315 | 2000 |
| Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7 MN Holowaty, M Zeghouf, H Wu, J Tellam, V Athanasopoulos, ... Journal of Biological Chemistry 278 (32), 29987-29994, 2003 | 310 | 2003 |
| Crystal structure of the DNA-binding domain of the Epstein–Barr virus origin-binding protein, EBNA1, bound to DNA A Bochkarev, JA Barwell, RA Pfuetzner, E Bochkareva, L Frappier, ... Cell 84 (5), 791-800, 1996 | 267 | 1996 |
| The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single‐stranded DNA binding A Bochkarev, E Bochkareva, L Frappier, AM Edwards The EMBO journal, 1999 | 237 | 1999 |
| Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP MN Holowaty, Y Sheng, T Nguyen, C Arrowsmith, L Frappier Journal of Biological Chemistry 278 (48), 47753-47761, 2003 | 215 | 2003 |
| EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance K Shire, DFJ Ceccarelli, TM Avolio-Hunter, L Frappier Journal of virology 73 (4), 2587-2595, 1999 | 213 | 1999 |
| Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA1 A Bochkarev, JA Barwell, RA Pfuetzner, W Furey Jr, AM Edwards, ... Cell 83 (1), 39-46, 1995 | 199 | 1995 |
| Overproduction, purification, and characterization of EBNA1, the origin binding protein of Epstein-Barr virus. L Frappier, M O'Donnell Journal of Biological Chemistry 266 (12), 7819-7826, 1991 | 188 | 1991 |
| Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies N Sivachandran, F Sarkari, L Frappier PLoS pathogens 4 (10), e1000170, 2008 | 187 | 2008 |
| Viral proteomics KL Maxwell, L Frappier Microbiology and Molecular Biology Reviews 71 (2), 398-411, 2007 | 171 | 2007 |
| The RPA32 subunit of human replication protein A contains a single-stranded DNA-binding domain E Bochkareva, L Frappier, AM Edwards, A Bochkarev Journal of biological chemistry 273 (7), 3932-3936, 1998 | 163 | 1998 |
| EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication F Sarkari, T Sanchez-Alcaraz, S Wang, MN Holowaty, Y Sheng, ... PLoS pathogens 5 (10), e1000624, 2009 | 160 | 2009 |
| Epstein-Barr nuclear antigen 1 mediates a DNA loop within the latent replication origin of Epstein-Barr virus. L Frappier, M O'Donnell Proceedings of the National Academy of Sciences 88 (23), 10875-10879, 1991 | 156 | 1991 |
| Separation of the DNA replication, segregation, and transcriptional activation functions of Epstein-Barr nuclear antigen 1 H Wu, P Kapoor, L Frappier Journal of virology 76 (5), 2480-2490, 2002 | 153 | 2002 |
| Contributions of Epstein–Barr nuclear antigen 1 (EBNA1) to cell immortalization and survival L Frappier Viruses 4 (9), 1537-1547, 2012 | 133 | 2012 |
| Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection N Sivachandran, X Wang, L Frappier Journal of virology 86 (11), 6146-6158, 2012 | 131 | 2012 |
Jack GreenblattProfessor, University of TorontoEmail verificata su utoronto.ca
