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Alexandre Goyon
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Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies
A Goyon, M Excoffier, MC Janin-Bussat, B Bobaly, S Fekete, D Guillarme, ...
Journal of Chromatography B 1065, 119-128, 2017
1762017
An online four-dimensional HIC× SEC-IM× MS methodology for proof-of-concept characterization of antibody drug conjugates
A Ehkirch, V d’Atri, F Rouviere, O Hernandez-Alba, A Goyon, O Colas, ...
Analytical chemistry 90 (3), 1578-1586, 2018
982018
Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation
A Goyon, V D’Atri, O Colas, S Fekete, A Beck, D Guillarme
Journal of Chromatography B 1065, 35-43, 2017
872017
Evaluation of size exclusion chromatography columns packed with sub-3 μm particles for the analysis of biopharmaceutical proteins
A Goyon, A Beck, O Colas, K Sandra, D Guillarme, S Fekete
Journal of Chromatography A 1498, 80-89, 2017
862017
Characterization of therapeutic oligonucleotides by liquid chromatography
A Goyon, P Yehl, K Zhang
Journal of Pharmaceutical and Biomedical Analysis 182, 113105, 2020
842020
Unraveling the mysteries of modern size exclusion chromatography-the way to achieve confident characterization of therapeutic proteins
A Goyon, S Fekete, A Beck, JL Veuthey, D Guillarme
Journal of Chromatography B 1092, 368-378, 2018
672018
Determination of 105 antibiotic, anti-inflammatory, antiparasitic agents and tranquilizers by LC-MS/MS based on an acidic QuEChERS-like extraction
A Desmarchelier, K Fan, M Minh Tien, MC Savoy, A Tarres, D Fuger, ...
Food Additives & Contaminants: Part A 35 (4), 647-661, 2018
672018
Protocols for the analytical characterization of therapeutic monoclonal antibodies. II–Enzymatic and chemical sample preparation
B Bobaly, V D’Atri, A Goyon, O Colas, A Beck, S Fekete, D Guillarme
Journal of Chromatography B 1060, 325-335, 2017
672017
A novel online four-dimensional SEC× SEC-IM× MS methodology for characterization of monoclonal antibody size variants
A Ehkirch, A Goyon, O Hernandez-Alba, F Rouviere, V D’atri, C Dreyfus, ...
Analytical chemistry 90 (23), 13929-13937, 2018
642018
Determination of steroid hormones in bovine milk by LC-MS/MS and their levels in Swiss Holstein cow milk
A Goyon, JZ Cai, K Kraehenbuehl, C Hartmann, B Shao, P Mottier
Food Additives & Contaminants: Part A 33 (5), 804-816, 2016
602016
Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches
J Camperi, A Goyon, D Guillarme, K Zhang, C Stella
Analyst 146 (3), 747-769, 2021
592021
From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant …
A Goyon, L Dai, T Chen, B Wei, F Yang, N Andersen, R Kopf, M Leiss, ...
Journal of Chromatography A 1615, 460740, 2020
542020
Protocols for the analytical characterization of therapeutic monoclonal antibodies. I–Non-denaturing chromatographic techniques
A Goyon, V D’Atri, B Bobaly, E Wagner-Rousset, A Beck, S Fekete, ...
Journal of Chromatography B 1058, 73-84, 2017
542017
Characterization of antisense oligonucleotide impurities by ion-pairing reversed-phase and anion exchange chromatography coupled to hydrophilic interaction liquid …
A Goyon, K Zhang
Analytical chemistry 92 (8), 5944-5951, 2020
512020
Streamlined characterization of an antibody–drug conjugate by two-dimensional and four-dimensional liquid chromatography/mass spectrometry
A Goyon, M Kim, L Dai, C Cornell, F Jacobson, D Guillarme, C Stella
Analytical chemistry 91 (23), 14896-14903, 2019
492019
Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals
A Goyon, A Beck, JL Veuthey, D Guillarme, S Fekete
Journal of pharmaceutical and biomedical analysis 144, 242-251, 2017
412017
Clinical and vitamin response to a short‐term multi‐micronutrient intervention in Brazilian children and teens: From population data to interindividual responses
MG Mathias, CA Coelho‐Landell, MP Scott‐Boyer, S Lacroix, MJ Morine, ...
Molecular nutrition & food research 62 (6), 1700613, 2018
352018
Full sequencing of CRISPR/Cas9 single guide RNA (sgRNA) via parallel ribonuclease digestions and hydrophilic interaction liquid chromatography–high-resolution mass spectrometry …
A Goyon, B Scott, K Kurita, CM Crittenden, D Shaw, A Lin, P Yehl, ...
Analytical Chemistry 93 (44), 14792-14801, 2021
342021
Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities
E Wagner, O Colas, S Chenu, A Goyon, A Murisier, S Cianferani, ...
Journal of pharmaceutical and biomedical analysis 184, 113166, 2020
342020
Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticles
Y Fan, CW Yen, HC Lin, W Hou, A Estevez, A Sarode, A Goyon, J Bian, ...
International journal of pharmaceutics 599, 120392, 2021
332021
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