Amit Singh
Amit Singh
Associate Professor, IISc
Verified email at - Homepage
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Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response
A Singh, DK Crossman, D Mai, L Guidry, MI Voskuil, MB Renfrow, ...
PLoS Pathog 5 (8), e1000545, 2009
Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival
A Singh, L Guidry, KV Narasimhulu, D Mai, J Trombley, KE Redding, ...
Proceedings of the National Academy of Sciences 104 (28), 11562-11567, 2007
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs
R Singh, V Rao, H Shakila, R Gupta, A Khera, N Dhar, A Singh, A Koul, ...
Molecular microbiology 50 (3), 751-762, 2003
Dissecting virulence pathways of Mycobacterium tuberculosis through protein–protein association
A Singh, D Mai, A Kumar, AJC Steyn
Proceedings of the National Academy of Sciences 103 (30), 11346-11351, 2006
Reengineering redox sensitive GFP to measure mycothiol redox potential of Mycobacterium tuberculosis during infection
A Bhaskar, M Chawla, M Mehta, P Parikh, P Chandra, D Bhave, D Kumar, ...
PLoS Pathog 10 (1), e1003902, 2014
Role of Mycobacterium tuberculosis Ser/Thr kinase PknF: implications in glucose transport and cell division
P Deol, R Vohra, AK Saini, A Singh, H Chandra, P Chopra, TK Das, ...
Journal of bacteriology 187 (10), 3415-3420, 2005
Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of guinea pigs
A Singh, R Gupta, RA Vishwakarma, PR Narayanan, CN Paramasivan, ...
Journal of bacteriology 187 (12), 4173-4186, 2005
mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope
A Singh, S Jain, S Gupta, T Das, AK Tyagi
FEMS microbiology letters 227 (1), 53-63, 2003
Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo
M Chawla, P Parikh, A Saxena, MH Munshi, M Mehta, D Mai, ...
Molecular microbiology 85 (6), 1148-1165, 2012
Glucose metabolism in T cells and monocytes: new perspectives in HIV pathogenesis
CS Palmer, CL Cherry, I Sada-Ovalle, A Singh, SM Crowe
EBioMedicine 6, 31-41, 2016
Mycobacterium tuberculosis Inhibits RAB7 Recruitment to Selectively Modulate Autophagy Flux in Macrophages
P Chandra, S Ghanwat, SK Matta, SS Yadav, M Mehta, Z Siddiqui, ...
Scientific reports 5, 16320, 2015
Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide
P Tyagi, AT Dharmaraja, A Bhaskar, H Chakrapani, A Singh
Free Radical Biology and Medicine 84, 344-354, 2015
Mycobacterium tuberculosis WhiB3 responds to vacuolar pH-induced changes in mycothiol redox potential to modulate phagosomal maturation and virulence
M Mehta, RS Rajmani, A Singh
Journal of Biological Chemistry 291 (6), 2888-2903, 2016
Protein kinase G confers survival advantage to Mycobacterium tuberculosis during latency-like conditions
MZ Khan, A Bhaskar, S Upadhyay, P Kumari, RS Rajmani, P Jain, ...
Journal of Biological Chemistry 292 (39), 16093-16108, 2017
Reductive stress in microbes: implications for understanding Mycobacterium tuberculosis disease and persistence
A Farhana, L Guidry, A Srivastava, A Singh, MK Hondalus, AJC Steyn
Advances in microbial physiology 57, 43-117, 2010
Measuring glutathione redox potential of HIV-1-infected macrophages
A Bhaskar, MH Munshi, SZ Khan, S Fatima, R Arya, S Jameel, A Singh
Journal of Biological Chemistry 290 (2), 1020-1038, 2015
“On demand” redox buffering by H 2 S contributes to antibiotic resistance revealed by a bacteria-specific H 2 S donor
P Shukla, VS Khodade, M SharathChandra, P Chauhan, S Mishra, ...
Chemical science 8 (7), 4967-4972, 2017
Express path analysis identifies a tyrosine kinase Src-centric network regulating divergent host responses to Mycobacterium tuberculosis infection
AF Karim, P Chandra, A Chopra, Z Siddiqui, A Bhaskar, A Singh, D Kumar
Journal of Biological Chemistry 286 (46), 40307-40319, 2011
Deciphering the genes involved in pathogenesis of Mycobacterium tuberculosis
R Singh, A Singh, AK Tyagi
Tuberculosis 85 (5-6), 325-335, 2005
First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis
PB Palde, A Bhaskar, LE Pedró Rosa, F Madoux, P Chase, V Gupta, ...
ACS chemical biology 11 (1), 172-184, 2016
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