| Design of amidobenzimidazole STING receptor agonists with systemic activity JM Ramanjulu, GS Pesiridis, J Yang, N Concha, R Singhaus, SY Zhang, ... Nature 564 (7736), 439-443, 2018 | 562 | 2018 |
| Big opportunities for small molecules in immuno-oncology JL Adams, J Smothers, R Srinivasan, A Hoos Nature reviews Drug discovery 14 (9), 603-622, 2015 | 471 | 2015 |
| The BRAF and MEK inhibitors dabrafenib and trametinib: effects on immune function and in combination with immunomodulatory antibodies targeting PD-1, PD-L1, and CTLA-4 L Liu, PA Mayes, S Eastman, H Shi, S Yadavilli, T Zhang, J Yang, ... Clinical Cancer Research 21 (7), 1639-1651, 2015 | 435 | 2015 |
| Molecular evidence that the myxozoan protists are metazoans JF Smothers, CD von Dohlen, LH Smith Jr, RD Spall Science 265 (5179), 1719-1721, 1994 | 314 | 1994 |
| The HP1 chromo shadow domain binds a consensus peptide pentamer JF Smothers, S Henikoff Current Biology 10 (1), 27-30, 2000 | 307 | 2000 |
| Distinct HP1 and Su (var) 3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location F Greil, I Van Der Kraan, J Delrow, JF Smothers, E De Wit, ... Genes & development 17 (22), 2825-2838, 2003 | 205 | 2003 |
| Pdd1p, a novel chromodomain-containing protein, links heterochromatin assembly and DNA elimination in Tetrahymena MT Madireddi, RS Coyne, JF Smothers, KM Mickey, MC Yao, CD Allis Cell 87 (1), 75-84, 1996 | 201 | 1996 |
| The hinge and chromo shadow domain impart distinct targeting of HP1-like proteins JF Smothers, S Henikoff Molecular and cellular biology 21 (7), 2555-2569, 2001 | 198 | 2001 |
| Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments JW Yu, S Bhattacharya, N Yanamandra, D Kilian, H Shi, S Yadavilli, ... PloS one 13 (11), e0206223, 2018 | 184 | 2018 |
| Parental expression of the chromodomain protein Pdd1p is required for completion of programmed DNA elimination and nuclear differentiation RS Coyne, MA Nikiforov, JF Smothers, CD Allis, MC Yao Molecular cell 4 (5), 865-872, 1999 | 119 | 1999 |
| Affinity selection from biological libraries JF Smothers, S Henikoff, P Carter Science 298 (5593), 621-622, 2002 | 115 | 2002 |
| Excision of micronuclear-specific DNA requires parental expression of Pdd2p andoccursindependentlyfromDNA replication in Tetrahymena thermophila MA Nikiforov, JF Smothers, MA Gorovsky, CD Allis Genes & development 13 (21), 2852-2862, 1999 | 80 | 1999 |
| Human C-FMS antigen binding proteins KA Brasel, JF Smothers, DP Cerretti US Patent 8,182,813, 2012 | 64 | 2012 |
| Pdd1p associates with germline-restricted chromatin and a second novel anlagen-enriched protein in developmentally programmed DNA elimination structures JF Smothers, CA Mizzen, MM Tubbert, RG Cook, CD Allis Development 124 (22), 4537-4545, 1997 | 64 | 1997 |
| Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo R Montes de Oca, AS Alavi, N Vitali, S Bhattacharya, C Blackwell, K Patel, ... Molecular cancer therapeutics 20 (10), 1941-1955, 2021 | 57 | 2021 |
| Clinical and pharmacodynamic (PD) results of a phase I trial with AMP-224 (B7-DC Fc) that binds to the PD-1 receptor. JR Infante, JD Powderly, HA Burris, M Kittaneh, JH Grice, JF Smothers, ... Journal of Clinical Oncology 31 (15_suppl), 3044-3044, 2013 | 46 | 2013 |
| IL-17 receptor A antigen binding proteins J Tocker, JJ Peschon, JF Smothers US Patent 7,939,070, 2011 | 45* | 2011 |
| Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma W Peng, LJ Williams, C Xu, B Melendez, JA McKenzie, Y Chen, ... Clinical Cancer Research 25 (21), 6406-6416, 2019 | 41 | 2019 |
| A Nonessential HP1-Like Protein Affects Starvation-Induced Assembly of Condensed Chromatin and Gene Expression in Macronuclei of Tetrahymena thermophila H Huang, JF Smothers, EA Wiley, CD Allis Molecular and cellular biology 19 (5), 3624-3634, 1999 | 32 | 1999 |
| Programmed DNA degradation and nucleolar biogenesis occur in distinct organelles during macronuclear development in Tetrahymena JF SMOTHERS, MT MADIREDDI, FD WARNER, CD ALLIS Journal of Eukaryotic Microbiology 44 (2), 79-88, 1997 | 32 | 1997 |
