| Small-molecule inhibitors of protein geranylgeranyltransferase type I S Castellano, HDG Fiji, SS Kinderman, M Watanabe, P de Leon, ... Journal of the American Chemical Society 129 (18), 5843-5845, 2007 | 222 | 2007 |
| Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees A Spannhoff, YK Kim, NJM Raynal, V Gharibyan, MB Su, YY Zhou, J Li, ... EMBO reports 12 (3), 238-243, 2011 | 220 | 2011 |
| Antimycobacterial activity of ionic fullerene derivatives S Bosi, T Da Ros, S Castellano, E Banfi, M Prato Bioorganic & medicinal chemistry letters 10 (10), 1043-1045, 2000 | 203 | 2000 |
| Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors S Castellano, D Kuck, M Viviano, J Yoo, F López-Vallejo, P Conti, ... Journal of medicinal chemistry 54 (21), 7663-7677, 2011 | 190 | 2011 |
| Design and synthesis of novel [60] fullerene derivatives as potential HIV aspartic protease inhibitors GL Marcorin, T Da Ros, S Castellano, G Stefancich, I Bonin, S Miertus, ... Organic letters 2 (25), 3955-3958, 2000 | 177 | 2000 |
| 11C-ER176, a radioligand for 18-kDa translocator protein, has adequate sensitivity to robustly image all three affinity genotypes in human brain M Ikawa, TG Lohith, S Shrestha, S Telu, SS Zoghbi, S Castellano, ... Journal of Nuclear Medicine 58 (2), 320-325, 2017 | 137 | 2017 |
| Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases G Sbardella, S Castellano, C Vicidomini, D Rotili, A Nebbioso, M Miceli, ... Bioorganic & medicinal chemistry letters 18 (9), 2788-2792, 2008 | 128 | 2008 |
| Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations R Ragno, S Simeoni, S Castellano, C Vicidomini, A Mai, A Caroli, ... Journal of medicinal chemistry 50 (6), 1241-1253, 2007 | 126 | 2007 |
| Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart C Colussi, J Rosati, S Straino, F Spallotta, R Berni, D Stilli, S Rossi, ... Proceedings of the National Academy of Sciences 108 (7), 2795-2800, 2011 | 121 | 2011 |
| Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1 S Castellano, D Kuck, M Sala, E Novellino, F Lyko, G Sbardella Journal of medicinal chemistry 51 (7), 2321-2325, 2008 | 121 | 2008 |
| Tau-centric multitarget approach for Alzheimer’s disease: development of first-in-class dual glycogen synthase kinase 3β and tau-aggregation inhibitors A Gandini, M Bartolini, D Tedesco, L Martinez-Gonzalez, C Roca, ... Journal of medicinal chemistry 61 (17), 7640-7656, 2018 | 104 | 2018 |
| p300/CBP-associated factor selectively regulates the extinction of conditioned fear W Wei, CM Coelho, X Li, R Marek, S Yan, S Anderson, D Meyers, ... Journal of Neuroscience 32 (35), 11930-11941, 2012 | 102 | 2012 |
| Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases A Mai, D Rotili, D Tarantino, A Nebbioso, S Castellano, G Sbardella, ... Bioorganic & medicinal chemistry letters 19 (4), 1132-1135, 2009 | 97 | 2009 |
| The emerging role of lysine methyltransferase SETD8 in human diseases C Milite, A Feoli, M Viviano, D Rescigno, A Cianciulli, AL Balzano, A Mai, ... Clinical epigenetics 8, 1-15, 2016 | 91 | 2016 |
| Novel 3, 5-bis (bromohydroxybenzylidene) piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity D Cheng, S Valente, S Castellano, G Sbardella, R Di Santo, R Costi, ... Journal of medicinal chemistry 54 (13), 4928-4932, 2011 | 89 | 2011 |
| The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients M Vecellio, F Spallotta, S Nanni, C Colussi, C Cencioni, A Derlet, ... Diabetes 63 (6), 2132-2147, 2014 | 83 | 2014 |
| Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide … P Zanotti-Fregonara, Y Zhang, KJ Jenko, RL Gladding, SS Zoghbi, ... ACS chemical neuroscience 5 (10), 963-971, 2014 | 75 | 2014 |
| Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI‐1) S Castellano, C Milite, R Ragno, S Simeoni, A Mai, V Limongelli, ... ChemMedChem 5 (3), 398-414, 2010 | 72 | 2010 |
| A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach C Milite, A Feoli, K Sasaki, V La Pietra, AL Balzano, L Marinelli, A Mai, ... Journal of medicinal chemistry 58 (6), 2779-2798, 2015 | 59 | 2015 |
| Diversity through a branched reaction pathway: Generation of multicyclic scaffolds and identification of antimigratory agents Z Wang, S Castellano, SS Kinderman, CE Argueta, AB Beshir, ... Chemistry–A European Journal 17 (2), 649-654, 2011 | 59 | 2011 |
