| Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, SM Meng, ... Nature Biomedical Engineering 5 (6), 600-612, 2021 | 177 | 2021 |
| Advanced methodologies in high-throughput sequencing of immune repertoires S Friedensohn, TA Khan, ST Reddy Trends in biotechnology 35 (3), 203-214, 2017 | 134 | 2017 |
| Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting TA Khan, S Friedensohn, AR Gorter de Vries, J Straszewski, ... Science advances 2 (3), e1501371, 2016 | 130 | 2016 |
| Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice V Greiff, U Menzel, U Haessler, SC Cook, S Friedensohn, TA Khan, ... BMC immunology 15, 1-14, 2014 | 67 | 2014 |
| Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing U Menzel, V Greiff, TA Khan, U Haessler, I Hellmann, S Friedensohn, ... PloS one 9 (5), e96727, 2014 | 66 | 2014 |
| Deep learning enables therapeutic antibody optimization in mammalian cells by deciphering high-dimensional protein sequence space DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, S Meng, ... BioRxiv, 617860, 2019 | 51 | 2019 |
| Convergent selection in antibody repertoires is revealed by deep learning S Friedensohn, D Neumeier, TA Khan, L Csepregi, C Parola, ... BioRxiv, 2020.02. 25.965673, 2020 | 41 | 2020 |
| Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen F Sesterhenn, M Galloux, SS Vollers, L Csepregi, C Yang, D Descamps, ... PLoS biology 17 (2), e3000164, 2019 | 35 | 2019 |
| Synthetic standards combined with error and bias correction improve the accuracy and quantitative resolution of antibody repertoire sequencing in human naïve and memory B cells S Friedensohn, JM Lindner, V Cornacchione, M Iazeolla, E Miho, A Zingg, ... Frontiers in Immunology 9, 1401, 2018 | 33 | 2018 |
| Antibody discovery and engineering by enhanced CRISPR-Cas9 integration of variable gene cassette libraries in mammalian cells C Parola, D Neumeier, S Friedensohn, L Csepregi, M Di Tacchio, ... MAbs 11 (8), 1367-1380, 2019 | 27 | 2019 |
| SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ... Cell reports 38 (3), 2022 | 14 | 2022 |
| Cis-regulatory variation: significance in biomedicine and evolution S Friedensohn, R Sawarkar Cell and tissue research 356, 495-505, 2014 | 8 | 2014 |
| Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2 RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ... BioRxiv, 2021.02. 12.430940, 2021 | 7 | 2021 |
| The physiological landscape and specificity of antibody repertoires L Csepregi, KB Hoehn, D Neumeier, JM Taft, S Friedensohn, CR Weber, ... bioRxiv, 2021.09. 15.460420, 2021 | 5 | 2021 |
| Systems and methods to classify antibodies D Mason, S Friedensohn, C Weber, S Reddy US Patent App. 17/439,374, 2022 | 3 | 2022 |
| Identification of convergent antibody specificity sequence patterns S Friedensohn, S Reddy US Patent App. 17/442,465, 2022 | | 2022 |
| Mining the sequence space of antibody repertoires to predict and design antigen-specific antibodies S Friedensohn ETH Zurich, 2020 | | 2020 |
| High-throughput sequencing error and bias correction increases the quantitative resolution of human naïve and memory B-cell receptor repertoires JM Lindner, S Friedensohn, V Cornacchione, M Iazeolla, E Miho, A Zingg, ... BioRxiv Preprint Server, 2018 | | 2018 |
| Correlations of antibody response phenotype to genotype revealed by molecular amplification fingerprinting ST Reddy, TA Khan, S Friedensohn, AR Gorter de Vries | | 2016 |
Sai T. ReddyAssociate Professor, ETH ZurichEmail verificata su bsse.ethz.ch
