ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity F Belmonte, S Das, P Sysa-Shah, V Sivakumaran, B Stanley, X Guo, ... American Journal of Physiology-Heart and Circulatory Physiology 309 (8 …, 2015 | 105 | 2015 |
LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson’s disease EH Howlett, N Jensen, F Belmonte, F Zafar, X Hu, J Kluss, B Schüle, ... Human molecular genetics 26 (22), 4340-4351, 2017 | 94 | 2017 |
Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions. MATBAK Frances R. Belmonte, James L. Martin, Kristin Frescura, Joana Damas ... Scientific Reports 6, 25186, 2016 | 84 | 2016 |
Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice P Sysa-Shah, Y Xu, X Guo, F Belmonte, B Kang, D Bedja, S Pin, ... Public Library of Science 7 (8), e42805, 2012 | 61 | 2012 |
Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways P Sysa-Shah, CG Tocchetti, M Gupta, PP Rainer, X Shen, BH Kang, ... Cardiovascular research 109 (3), 358-373, 2016 | 52 | 2016 |
Inactivation of Pif1 helicase causes a mitochondrial myopathy in mice S Bannwarth, L Berg-Alonso, G Augé, K Fragaki, JE Kolesar, ... Mitochondrion 30, 126-137, 2016 | 34 | 2016 |
Longitudinal studies of patients with ANCA vasculitis demonstrate concurrent reactivity to complementary PR3 protein segments cPR3m and cPR3C and with no reactivity to cPR3N P Hewins, F Belmonte, J Charles Jennette, RJ Falk, GA Preston Autoimmunity 44 (2), 98-106, 2011 | 19 | 2011 |
Validation and clinical performance of a combined nuclear‐mitochondrial next‐generation sequencing and copy number variant analysis panel in a Canadian population MA Levy, J Kerkhof, FR Belmonte, BA Kaufman, P Bhai, L Brady, ... American Journal of Medical Genetics Part A 185 (2), 486-499, 2021 | 7 | 2021 |
Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance FR Belmonte, N Dedousis, I Sipula, NA Desai, AD Singhi, Y Chu, Y Zhang, ... Plos one 14 (5), e0203101, 2019 | 7 | 2019 |
Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension YY Tai, Q Yu, Y Tang, W Sun, NJ Kelly, S Okawa, J Zhao, ... Science Translational Medicine 16 (729), eadd2029, 2024 | 1 | 2024 |
Hypoxia-Driven Long Noncoding RNA KMT2E-AS1 Modulates Histone Methylation to Control Endothelial Metabolic Reprogramming and Pulmonary Hypertension Q Yu, YY Tai, Y Tang, J Zhao, V Negi, AL Handen, CG Corey, ... Circulation 140 (Suppl_1), A13074-A13074, 2019 | | 2019 |
Myofilament Tyrosine Phosphorylation by Src Kinase is upregulated in ErbB2 Transgenic Mice M Xu, GA Ramirez-Correa, Z Fu, PS Shah, F Belmonte, K Gabrielson, ... Circulation Research 117 (suppl_1), A268-A268, 2015 | | 2015 |