| Genome-scale identification of nucleosome positions in S. cerevisiae GC Yuan, YJ Liu, MF Dion, MD Slack, LF Wu, SJ Altschuler, OJ Rando Science 309 (5734), 626-630, 2005 | 1358 | 2005 |
| EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency X Shen, Y Liu, YJ Hsu, Y Fujiwara, J Kim, X Mao, GC Yuan, SH Orkin Molecular cell 32 (4), 491-502, 2008 | 854 | 2008 |
| Lagrangian coherent structures and mixing in two-dimensional turbulence G Haller, G Yuan Physica D: Nonlinear Phenomena 147 (3-4), 352-370, 2000 | 833 | 2000 |
| Mapping the mouse cell atlas by microwell-seq X Han, R Wang, Y Zhou, L Fei, H Sun, S Lai, A Saadatpour, Z Zhou, ... Cell 172 (5), 1091-1107. e17, 2018 | 660 | 2018 |
| BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015 | 583 | 2015 |
| An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level DE Bauer, SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, ... Science 342 (6155), 253-257, 2013 | 466 | 2013 |
| Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells X Shen, W Kim, Y Fujiwara, MD Simon, Y Liu, MR Mysliwiec, GC Yuan, ... cell 139 (7), 1303-1314, 2009 | 425 | 2009 |
| LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity G Wu, J Cai, Y Han, J Chen, ZP Huang, C Chen, Y Cai, H Huang, Y Yang, ... Circulation 130 (17), 1452-1465, 2014 | 397 | 2014 |
| High-fat diet enhances stemness and tumorigenicity of intestinal progenitors S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ... Nature 531 (7592), 53-58, 2016 | 388 | 2016 |
| CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer E Chipumuro, E Marco, CL Christensen, N Kwiatkowski, T Zhang, ... Cell 159 (5), 1126-1139, 2014 | 375 | 2014 |
| MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets Z Shao, Y Zhang, GC Yuan, SH Orkin, DJ Waxman Genome biology 13 (3), 1-17, 2012 | 369 | 2012 |
| Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+ CHL Eng, M Lawson, Q Zhu, R Dries, N Koulena, Y Takei, J Yun, ... Nature 568 (7751), 235-239, 2019 | 368 | 2019 |
| A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing D Pan, A Kobayashi, P Jiang, LF de Andrade, RE Tay, AM Luoma, ... Science 359 (6377), 770-775, 2018 | 345 | 2018 |
| Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors J Riddell, R Gazit, BS Garrison, G Guo, A Saadatpour, PK Mandal, ... Cell 157 (3), 549-564, 2014 | 297 | 2014 |
| Analyzing CRISPR genome-editing experiments with CRISPResso L Pinello, MC Canver, MD Hoban, SH Orkin, DB Kohn, DE Bauer, ... Nature biotechnology 34 (7), 695-697, 2016 | 282 | 2016 |
| Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae AB Lantermann, T Straub, A Strålfors, GC Yuan, K Ekwall, P Korber Nature structural & molecular biology 17 (2), 251, 2010 | 249 | 2010 |
| Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire G Guo, S Luc, E Marco, TW Lin, C Peng, MA Kerenyi, S Beyaz, W Kim, ... Cell stem cell 13 (4), 492-505, 2013 | 233 | 2013 |
| Genomic sequence is highly predictive of local nucleosome depletion GC Yuan, JS Liu PLoS Comput Biol 4 (1), e13, 2008 | 222 | 2008 |
| Bifurcation analysis of single-cell gene expression data reveals epigenetic landscape E Marco, RL Karp, G Guo, P Robson, AH Hart, L Trippa, GC Yuan Proceedings of the National Academy of Sciences 111 (52), E5643-E5650, 2014 | 221 | 2014 |
| Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation R Fang, AJ Barbera, Y Xu, M Rutenberg, T Leonor, Q Bi, F Lan, P Mei, ... Molecular cell 39 (2), 222-233, 2010 | 210 | 2010 |
Stuart OrkinVerified email at dfci.harvard.edu
