H Eric Xu
H Eric Xu
Professor and Director, Key Lab for Receptor Research, Shanghai Institute of Material Medica
Email verificata su simm.ac.cn
Citata da
Citata da
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport
WR Oliver, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ...
Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001
Molecular recognition of fatty acids by peroxisome proliferator–activated receptors
HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ...
Molecular cell 3 (3), 397-403, 1999
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
RK Bledsoe, VG Montana, TB Stanley, CJ Delves, CJ Apolito, DD McKee, ...
Cell 110 (1), 93-105, 2002
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPAR α
HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ...
Nature 415 (6873), 813-817, 2002
Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
RT Gampe Jr, VG Montana, MH Lambert, AB Miller, RK Bledsoe, ...
Molecular cell 5 (3), 545-555, 2000
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ...
Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001
A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors
K Melcher, LM Ng, XE Zhou, FF Soon, Y Xu, KM Suino-Powell, SY Park, ...
Nature 462 (7273), 602-608, 2009
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ...
Nature 523 (7562), 561-567, 2015
Structural features for functional selectivity at serotonin receptors
D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ...
Science 340 (6132), 615-619, 2013
Peroxisome proliferator-activated receptors: from genes to physiology.
SA Kliewer, HE Xu, MH Lambert, TM Willson
Recent progress in hormone research 56, 239-263, 2001
Identification of a physiologically relevant endogenous ligand for PPARα in liver
MV Chakravarthy, IJ Lodhi, L Yin, RRV Malapaka, HE Xu, J Turk, ...
Cell 138 (3), 476-488, 2009
DWARF 53 acts as a repressor of strigolactone signalling in rice
L Jiang, X Liu, G Xiong, H Liu, F Chen, L Wang, X Meng, G Liu, H Yu, ...
Nature 504 (7480), 401-405, 2013
Digoxin and its derivatives suppress TH 17 cell differentiation by antagonizing RORγt activity
JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ...
Nature 472 (7344), 486-490, 2011
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans
DL Motola, CL Cummins, V Rottiers, KK Sharma, T Li, Y Li, ...
Cell 124 (6), 1209-1223, 2006
Structural basis for molecular recognition of folic acid by folate receptors
C Chen, J Ke, XE Zhou, W Yi, JS Brunzelle, J Li, EL Yong, HE Xu, ...
Nature 500 (7463), 486-489, 2013
FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis
S Kir, SA Beddow, VT Samuel, P Miller, SF Previs, K Suino-Powell, HE Xu, ...
Science 331 (6024), 1621-1624, 2011
Structural basis for molecular recognition at serotonin receptors
C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ...
Science 340 (6132), 610-614, 2013
Androgen receptor: structure, role in prostate cancer and drug discovery
MHE Tan, J Li, HE Xu, K Melcher, E Yong
Acta Pharmacologica Sinica 36 (1), 3-23, 2015
Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity
ML Sznaidman, CD Haffner, PR Maloney, A Fivush, E Chao, D Goreham, ...
Bioorganic & medicinal chemistry letters 13 (9), 1517-1521, 2003
Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases
FF Soon, LM Ng, XE Zhou, GM West, A Kovach, MH Tan, ...
Science 335 (6064), 85, 2012
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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