| AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor GA Donzella, D Schols, SW Lin, JA Esté, KA Nagashima, PJ Maddon, ... Nature medicine 4 (1), 72, 1998 | 855 | 1998 |
| Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin TP Sakmar, RR Franke, HG Khorana Proceedings of the National Academy of Sciences 86 (21), 8309-8313, 1989 | 758 | 1989 |
| Defeating Alzheimer's disease and other dementias: a priority for European science and society B Winblad, P Amouyel, S Andrieu, C Ballard, C Brayne, H Brodaty, ... The Lancet Neurology 15 (5), 455-532, 2016 | 719 | 2016 |
| A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5 T Dragic, A Trkola, DAD Thompson, EG Cormier, FA Kajumo, E Maxwell, ... Proceedings of the National Academy of Sciences 97 (10), 5639-5644, 2000 | 559 | 2000 |
| Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F SP Sheikh, TA Zvyaga, O Lichtarge, TP Sakmar, HR Bourne nature 383 (6598), 347, 1996 | 462 | 1996 |
| Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin SS Karnik, TP Sakmar, HB Chen, HG Khorana Proceedings of the National Academy of Sciences 85 (22), 8459-8463, 1988 | 441 | 1988 |
| Rhodopsin mutants that bind but fail to activate transducin RR Franke, B Konig, TP Sakmar, HG Khorana, KP Hofmann Science 250 (4977), 123-125, 1990 | 401 | 1990 |
| Rhodopsin: structural basis of molecular physiology ST Menon, M Han, TP Sakmar Physiological reviews 81 (4), 1659-1688, 2001 | 360 | 2001 |
| Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin. RR Franke, TP Sakmar, RM Graham, HG Khorana Journal of Biological Chemistry 267 (21), 14767-14774, 1992 | 329 | 1992 |
| G protein-coupled receptors self-assemble in dynamics simulations of model bilayers X Periole, T Huber, SJ Marrink, TP Sakmar Journal of the American Chemical Society 129 (33), 10126-10132, 2007 | 311 | 2007 |
| Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry T Dragic, A Trkola, SW Lin, KA Nagashima, F Kajumo, L Zhao, WC Olson, ... Journal of virology 72 (1), 279-285, 1998 | 290 | 1998 |
| A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin. RR Franke, TP Sakmar, DD Oprian, HG Khorana Journal of Biological Chemistry 263 (5), 2119-2122, 1988 | 286 | 1988 |
| Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants K Fahmy, F Jäger, M Beck, TA Zvyaga, TP Sakmar, F Siebert Proceedings of the National Academy of Sciences 90 (21), 10206-10210, 1993 | 280 | 1993 |
| Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry F Tsamis, S Gavrilov, F Kajumo, C Seibert, S Kuhmann, T Ketas, A Trkola, ... Journal of virology 77 (9), 5201-5208, 2003 | 274 | 2003 |
| CXCR7/CXCR4 heterodimer constitutively recruits β-arrestin to enhance cell migration FM Décaillot, MA Kazmi, Y Lin, S Ray-Saha, TP Sakmar, P Sachdev Journal of Biological Chemistry 286 (37), 32188-32197, 2011 | 271 | 2011 |
| Specific tryptophan UV-absorbance changes are probes of the transition of rhodopsin to its active state SW Lin, TP Sakmar Biochemistry 35 (34), 11149-11159, 1996 | 267 | 1996 |
| A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin. S Arnis, K Fahmy, KP Hofmann, TP Sakmar Journal of Biological Chemistry 269 (39), 23879-23881, 1994 | 261 | 1994 |
| Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes AV Botelho, T Huber, TP Sakmar, MF Brown Biophysical journal 91 (12), 4464-4477, 2006 | 256 | 2006 |
| Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12 CT Veldkamp, C Seibert, FC Peterson, B Norberto, JC Haugner, H Basnet, ... Sci. Signal. 1 (37), ra4-ra4, 2008 | 250 | 2008 |
| Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12 CT Veldkamp, C Seibert, FC Peterson, B Norberto, JC Haugner, H Basnet, ... Sci. Signal. 1 (37), ra4-ra4, 2008 | 250 | 2008 |
Steven O. SmithStony Brook UniversityVerified email at stonybrook.edu
