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Christopher Tape
Christopher Tape
Group Leader, University College London Cancer Institute
Verified email at ucl.ac.uk - Homepage
Title
Cited by
Cited by
Year
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
CJ Tape, S Ling, M Dimitriadi, K McMahon, JD Worboys, HS Leong, ...
Cell 165 (4), 2016
4062016
Thiol isomerases negatively regulate the cellular shedding activity of ADAM17
SH Willems, CJ Tape, PL Stanley, NA Taylor, IG Mills, DE Neal, ...
Biochemical Journal 428 (3), 439-450, 2010
2032010
Cross-domain inhibition of TACE ectodomain
CJ Tape, SH Willems, SL Dombernowsky, PL Stanley, M Fogarasi, ...
Proceedings of the National Academy of Sciences 108 (14), 5578-5583, 2011
1442011
Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis
R Natrajan, H Sailem, F Mardakheh, MA Garcia, CJ Tape, M Dowsett, ...
PLoS Medicine, 2016
1292016
Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance
JL Orgaz, E Crosas-Molist, A Sadok, A Perdrix-Rosell, O Maiques, ...
Cancer Cell 37 (1), 85-103. e9, 2020
1102020
Cell-type-specific signaling networks in heterocellular organoids
X Qin, J Sufi, P Vlckova, P Kyriakidou, SE Acton, VSW Li, M Nitz, CJ Tape
Nature methods 17 (3), 335-342, 2020
1012020
Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo
FM Richards, CJ Tape, DI Jodrell, G Murphy
PloS one 7 (7), e40597, 2012
1002012
Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC
CJ Tape, JD Worboys, J Sinclair, R Gourlay, J Vogt, KM McMahon, ...
Analytical chemistry 86 (20), 10296-10302, 2014
832014
Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination
M Montagner, R Bhome, S Hooper, P Chakravarty, X Qin, J Sufi, ...
Nature Cell Biology 22 (3), 289-296, 2020
742020
Targeting ADAM-17 with an inhibitory monoclonal antibody has antitumour effects in triple-negative breast cancer cells
F Caiazza, PM McGowan, M Mullooly, A Murray, N Synnott, N O'Donovan, ...
British Journal of Cancer 112 (12), 1895-1903, 2015
732015
Fibroblastic reticular cells control conduit matrix deposition during lymph node expansion
VG Martinez, V Pankova, L Krasny, T Singh, S Makris, IJ White, ...
Cell reports 29 (9), 2810-2822. e5, 2019
722019
Targeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1 (A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of …
Y Huang, N Benaich, C Tape, HF Kwok, G Murphy
International journal of biological sciences 10 (7), 702, 2014
532014
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)
S Santamaria, K Yamamoto, K Botkjaer, C Tape, MR Dyson, J McCafferty, ...
Biochemical journal 471 (3), 391-401, 2015
442015
Development of a ‘mouse and human cross-reactive’affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy
HF Kwok, KA Botkjaer, CJ Tape, Y Huang, J McCafferty, G Murphy
Protein Engineering, Design & Selection 27 (6), 179-190, 2014
392014
Cell-specific labeling enzymes for analysis of cell–cell communication in continuous co-culture
CJ Tape, IC Norrie, JD Worboys, L Lim, DA Lauffenburger, C Jørgensen
Molecular & Cellular Proteomics 13 (7), 1866-1876, 2014
362014
An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity
L Woodbine, S Grigoriadou, AA Goodarzi, E Riballo, C Tape, AW Oliver, ...
DNA repair 9 (9), 1003-1010, 2010
362010
Systems biology analysis of heterocellular signaling
CJ Tape
Trends in biotechnology 34 (8), 627-637, 2016
302016
Multiplexed single-cell analysis of organoid signaling networks
J Sufi, X Qin, FC Rodriguez, YJ Bu, P Vlckova, MR Zapatero, M Nitz, ...
Nature protocols 16 (10), 4897-4918, 2021
262021
The heterocellular emergence of colorectal cancer
CJ Tape
Trends in cancer 3 (2), 79-88, 2017
262017
Deciphering organoids: high-dimensional analysis of biomimetic cultures
X Qin, CJ Tape
Trends in Biotechnology 39 (8), 774-787, 2021
202021
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Articles 1–20