| Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors BK Koo, M Spit, I Jordens, TY Low, DE Stange, M Van De Wetering, ... Nature 488 (7413), 665-669, 2012 | 971 | 2012 |
| Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine RM Gadaleta, B Oldenburg, ECL Willemsen, M Spit, S Murzilli, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (8), 851-858, 2011 | 180 | 2011 |
| The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death E Lafont, C Kantari‐Mimoun, P Draber, D De Miguel, T Hartwig, ... The EMBO journal 36 (9), 1147-1166, 2017 | 125 | 2017 |
| Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer M Spit, BK Koo, MM Maurice Open biology 8 (9), 180120, 2018 | 124 | 2018 |
| Linear ubiquitination at a glance M Spit, E Rieser, H Walczak Journal of cell science 132 (2), jcs208512, 2019 | 78 | 2019 |
| Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network Z Anvarian, H Nojima, EC Van Kappel, T Madl, M Spit, M Viertler, ... Nature Structural & Molecular Biology 23 (4), 324-332, 2016 | 44 | 2016 |
| RNF 43 truncations trap CK 1 to drive niche‐independent self‐renewal in cancer M Spit, N Fenderico, I Jordens, T Radaszkiewicz, RGH Lindeboom, ... The EMBO Journal 39 (18), e103932, 2020 | 34 | 2020 |
| Current perspectives on inhibitory SMAD7 in health and disease C de Ceuninck van Capelle, M Spit, P ten Dijke Critical Reviews in Biochemistry and Molecular Biology 55 (6), 691-715, 2020 | 30 | 2020 |
| Current perspectives on inhibitory SMAD7 in health and disease CC van Capelle, M Spit, P Ten Dijke Critical reviews in biochemistry and molecular biology 55 (6), 691-715, 2020 | 28 | 2020 |
| Rectal hydrocortisone during stress in patients with adrenal insufficiency M De Vroede, R Beukering, M Spit, M Jansen Archives of disease in childhood 78 (6), 544-547, 1998 | 22 | 1998 |
| HETEROZYGOTES FOR 17α‐HYDROXYLASE DEFICIENCY CAN BE DETECTED WITH A SHORT ACTH TEST JM Wit, HPC Van Roermund, W Oostdijk, THJ Benraad, JHH Thijssen, ... Clinical endocrinology 28 (6), 657-664, 1988 | 20 | 1988 |
| Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity A Melão, M Spit, BA Cardoso, JT Barata Haematologica 101 (11), 1368, 2016 | 17 | 2016 |
| RNF43 truncating mutations mediate a tumour suppressor-to-oncogene switch to drive niche-independent self-renewal in cancer M Spit, N Fenderico, I Jordens, T Radaszkiewicz, RGH Lindeboom, ... bioRxiv, 748574, 2019 | 2 | 2019 |
| Alternative polyadenylation of APC mediates formation of a short N-terminal isoform that prevents beta-catenin turnover. M Omerzu, M Spit, B de Barbanson, I Kuper, J de Ridder, MM Maurice MOLECULAR BIOLOGY OF THE CELL 29 (26), 222-223, 2018 | | 2018 |
| OptimalIL-7R-mediatedsignaling, cellcycleprogressionandviabilityofT-cellacute lymphoblasticleukemiacellsrelyonCK2activity A Melão, M Spit, BA Cardoso, JT Barata | | 2016 |
| Balancing Wnt Signaling in Stem Cells and Cancer M Spit Utrecht University, 2015 | | 2015 |
| The role of Axin in beta-catenin-independent signaling M Spit | | 2010 |
