| Discovery of potent and selective covalent inhibitors of JNK T Zhang, F Inesta-Vaquera, M Niepel, J Zhang, SB Ficarro, T Machleidt, ... Chemistry & Biology 19 (1), 140-154, 2012 | 353 | 2012 |
| Crystal structure of a DNA decamer containing a cis-syn thymine dimer HJ Park, K Zhang, Y Ren, S Nadji, N Sinha, JS Taylor, CH Kang Proceedings of the National Academy of Sciences 99 (25), 15965-15970, 2002 | 271 | 2002 |
| Comparing skeletal and cardiac calsequestrin structures and their calcium binding: a proposed mechanism for coupled calcium binding and protein polymerization HJ Park, IY Park, EJ Kim, B Youn, K Fields, AK Dunker, CH Kang Journal of Biological Chemistry 279 (17), 18026-18033, 2004 | 178 | 2004 |
| The 1.5 Å crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding HJ Park, JC Boyington Journal of Biological Chemistry 285 (52), 40762-40770, 2010 | 167 | 2010 |
| Polymerization of Calsequestrin: IMPLICATIONS FOR Ca2+ REGULATION* 210 HJ Park, S Wu, AK Dunker, CH Kang Journal of Biological Chemistry 278 (18), 16176-16182, 2003 | 148 | 2003 |
| Insights into signal transduction involving PAS domain oxygen-sensing heme proteins from the X-ray crystal structure of Escherichia coli Dos heme domain (Ec DosH) Park, C Suquet, JD Satterlee, CH Kang Biochemistry 43 (10), 2738-2746, 2004 | 141 | 2004 |
| Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases T Min, H Kasahara, DL Bedgar, B Youn, PK Lawrence, DR Gang, ... Journal of Biological Chemistry 278 (50), 50714-50723, 2003 | 125 | 2003 |
| Pharmacological repression of PPARγ promotes osteogenesis DP Marciano, DS Kuruvilla, SV Boregowda, A Asteian, TS Hughes, ... Nature communications 6 (1), 7443, 2015 | 118 | 2015 |
| The 1.4 Å crystal structure of the human oxidized low density lipoprotein receptor Lox-1 HJ Park, FG Adsit, JC Boyington Journal of Biological Chemistry 280 (14), 13593-13599, 2005 | 110 | 2005 |
| Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules JL Childs-Disney, E Stepniak-Konieczna, T Tran, I Yildirim, HJ Park, ... Nature communications 4 (1), 2044, 2013 | 97 | 2013 |
| Crystal structure of the cytotoxic bacterial protein colicin B at 2.5 Å resolution JL Hilsenbeck, HJ Park, G Chen, B Youn, K Postle, CH Kang Molecular microbiology 51 (3), 711-720, 2004 | 97 | 2004 |
| Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1 J Qi, X Li, H Peng, EM Cook, EL Dadashian, A Wiestner, HJ Park, ... Proceedings of the National Academy of Sciences 115 (24), E5467-E5476, 2018 | 72 | 2018 |
| Structure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity JL Childs-Disney, I Yildirim, HJ Park, JR Lohman, L Guan, T Tran, ... ACS chemical biology 9 (2), 538-550, 2014 | 68 | 2014 |
| Interaction between cardiac calsequestrin and drugs with known cardiotoxicity IY Park, EJ Kim, HJ Park, K Fields, AK Dunker, CH Kang Molecular pharmacology 67 (1), 97-104, 2005 | 66 | 2005 |
| A dynamic structural model of expanded RNA CAG repeats: a refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations I Yildirim, HJ Park, MD Disney, GC Schatz Journal of the American Chemical Society 135 (9), 3528-3538, 2013 | 63 | 2013 |
| Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate‐bound state and S3P‐GLP‐bound state HJ Park, JL Hilsenbeck, HJ Kim, WA Shuttleworth, YH Park, JN Evans, ... Molecular microbiology 51 (4), 963-971, 2004 | 61 | 2004 |
| Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors Y Yin, K Zheng, N Eid, S Howard, JH Jeong, F Yi, J Guo, CM Park, ... Journal of medicinal chemistry 58 (4), 1846-1861, 2015 | 56 | 2015 |
| Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives K Zheng, S Iqbal, P Hernandez, HJ Park, PV LoGrasso, Y Feng Journal of medicinal chemistry 57 (23), 10013-10030, 2014 | 56 | 2014 |
| The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin HJ Park, JH Lee, E Gouin, P Cossart, T Izard Journal of Biological Chemistry 286 (40), 35096-35103, 2011 | 55 | 2011 |
| Myotonic dystrophy type 1 RNA crystal structures reveal heterogeneous 1× 1 nucleotide UU internal loop conformations A Kumar, HJ Park, P Fang, R Parkesh, M Guo, KW Nettles, MD Disney Biochemistry 50 (45), 9928-9935, 2011 | 52 | 2011 |
