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Michael W. Traxlmayr
Michael W. Traxlmayr
Head of the BOKU-module of the CD Lab for Next Generation CAR T Cells, BOKU University
Email verificata su boku.ac.at
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Citata da
Citata da
Anno
Protein engineering and selection using yeast surface display
A Angelini, TF Chen, S de Picciotto, NJ Yang, A Tzeng, MS Santos, ...
Yeast Surface Display: Methods, Protocols, and Applications, 3-36, 2015
1022015
Directed evolution of proteins for increased stability and expression using yeast display
MW Traxlmayr, C Obinger
Archives of biochemistry and biophysics 526 (2), 174-180, 2012
972012
Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function
B Salzer, CM Schueller, CU Zajc, T Peters, MA Schoeber, B Kovacic, ...
Nature Communications 11 (1), 4166, 2020
682020
An engineered protein antagonist of K-Ras/B-Raf interaction
MJ Kauke, MW Traxlmayr, JA Parker, JD Kiefer, R Knihtila, J McGee, ...
Scientific reports 7 (1), 5831, 2017
662017
Directed evolution of stabilized IgG1-Fc scaffolds by application of strong heat shock to libraries displayed on yeast
MW Traxlmayr, M Faissner, G Stadlmayr, C Hasenhindl, B Antes, F Rüker, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (4), 542-549, 2012
642012
A conformation-specific ON-switch for controlling CAR T cells with an orally available drug
CU Zajc, M Dobersberger, I Schaffner, G Mlynek, D Pühringer, B Salzer, ...
Proceedings of the National Academy of Sciences 117 (26), 14926-14935, 2020
632020
Strong enrichment of aromatic residues in binding sites from a charge-neutralized hyperthermostable Sso7d scaffold library
MW Traxlmayr, JD Kiefer, RR Srinivas, E Lobner, AW Tisdale, NK Mehta, ...
Journal of Biological Chemistry 291 (43), 22496-22508, 2016
622016
Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing
MW Traxlmayr, C Hasenhindl, M Hackl, G Stadlmayr, JD Rybka, N Borth, ...
Journal of molecular biology 423 (3), 397-412, 2012
572012
Engineered IgG1‐Fc–one fragment to bind them all
E Lobner, MW Traxlmayr, C Obinger, C Hasenhindl
Immunological reviews 270 (1), 113-131, 2016
542016
Immune suppression by γδ t-cells as a potential regulatory mechanism after cancer vaccination with IL-12 secreting dendritic cells
MW Traxlmayr, D Wesch, AM Dohnal, P Funovics, MB Fischer, D Kabelitz, ...
Journal of Immunotherapy 33 (1), 40-52, 2010
492010
Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display
MW Traxlmayr, E Lobner, B Antes, M Kainer, S Wiederkum, C Hasenhindl, ...
Protein Engineering, Design & Selection 26 (4), 255-265, 2013
442013
Activity-based assessment of an engineered hyperthermophilic protein as a capture agent in paper-based diagnostic tests
EA Miller, MW Traxlmayr, J Shen, HD Sikes
Molecular systems design & engineering 1 (4), 377-381, 2016
392016
Construction of pH‐sensitive Her2‐binding IgG1‐Fc by directed evolution
MW Traxlmayr, E Lobner, C Hasenhindl, G Stadlmayr, C Oostenbrink, ...
Biotechnology journal 9 (8), 1013-1022, 2014
362014
Fcab-HER2 interaction: a menage a trois. Lessons from X-Ray and solution studies
E Lobner, AS Humm, K Göritzer, G Mlynek, MG Puchinger, C Hasenhindl, ...
Structure 25 (6), 878-889. e5, 2017
292017
Directed evolution of protein thermal stability using yeast surface display
MW Traxlmayr, EV Shusta
Synthetic Antibodies: Methods and Protocols, 45-65, 2017
272017
Driving CARs with alternative navigation tools–the potential of engineered binding scaffolds
CU Zajc, B Salzer, JM Taft, ST Reddy, M Lehner, MW Traxlmayr
The FEBS journal 288 (7), 2103-2118, 2021
252021
Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc
C Hasenhindl, MW Traxlmayr, G Wozniak-Knopp, PC Jones, G Stadlmayr, ...
Protein Engineering, Design & Selection 26 (10), 675-682, 2013
242013
Integrin binding human antibody constant domains—probing the C-terminal structural loops for grafting the RGD motif
MW Traxlmayr, G Wozniak-Knopp, B Antes, G Stadlmayr, F Rüker, ...
Journal of biotechnology 155 (2), 193-202, 2011
242011
Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins
NJ Yang, MJ Kauke, F Sun, LF Yang, KF Maass, MW Traxlmayr, Y Yu, ...
Nucleic Acids Research 45 (13), 7602-7614, 2017
182017
Peroxidasin protein expression and enzymatic activity in metastatic melanoma cell lines are associated with invasive potential
M Paumann-Page, NF Kienzl, J Motwani, B Bathish, LN Paton, NJ Magon, ...
Redox Biology 46, 102090, 2021
172021
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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