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Sven Heinz
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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
S Heinz, C Benner, N Spann, E Bertolino, YC Lin, P Laslo, JX Cheng, ...
Molecular cell 38 (4), 576-589, 2010
112832010
The selection and function of cell type-specific enhancers
S Heinz, CE Romanoski, C Benner, CK Glass
Nature reviews Molecular cell biology 16 (3), 144-154, 2015
9822015
Genome evolution in the allotetraploid frog Xenopus laevis
AM Session, Y Uno, T Kwon, JA Chapman, A Toyoda, S Takahashi, ...
Nature 538 (7625), 336-343, 2016
9292016
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ...
Molecular cell 51 (3), 310-325, 2013
7042013
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
MTY Lam, H Cho, HP Lesch, D Gosselin, S Heinz, Y Tanaka-Oishi, ...
Nature 498 (7455), 511-515, 2013
5762013
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
YC Lin, S Jhunjhunwala, C Benner, S Heinz, E Welinder, R Mansson, ...
Nature immunology 11 (7), 635-643, 2010
5352010
Transcription elongation can affect genome 3D structure
S Heinz, L Texari, MGB Hayes, M Urbanowski, MW Chang, N Givarkes, ...
Cell 174 (6), 1522-1536. e22, 2018
3682018
Effect of natural genetic variation on enhancer selection and function
S Heinz, CE Romanoski, C Benner, KA Allison, MU Kaikkonen, ...
Nature 503 (7477), 487-492, 2013
3502013
Biomimetic morphogenesis of fluorapatite‐gelatin composites: Fractal growth, the question of intrinsic electric fields, core/shell assemblies, hollow spheres and reorganization …
S Busch, H Dolhaine, A DuChesne, S Heinz, O Hochrein, F Laeri, ...
European Journal of Inorganic Chemistry 1999 (10), 1643-1653, 1999
3081999
Global changes in the nuclear positioning of genes and intra-and interdomain genomic interactions that orchestrate B cell fate
YC Lin, C Benner, R Mansson, S Heinz, K Miyazaki, M Miyazaki, ...
Nature immunology 13 (12), 1196-1204, 2012
2942012
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity
M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ...
Immunity 51 (4), 655-670. e8, 2019
2592019
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
WQ Fan, H Morinaga, JJ Kim, E Bae, NJ Spann, S Heinz, CK Glass, ...
The EMBO journal 29 (24), 4223-4236, 2010
2542010
Species-specific regulation of Toll-like receptor 3 genes in men and mice
S Heinz, V Haehnel, M Karaghiosoff, L Schwarzfischer, M Muller, ...
Journal of Biological Chemistry 278 (24), 21502-21509, 2003
2492003
Human promoters are intrinsically directional
SHC Duttke, SA Lacadie, MM Ibrahim, CK Glass, DL Corcoran, C Benner, ...
Molecular cell 57 (4), 674-684, 2015
1542015
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation
A Rialdi, L Campisi, N Zhao, AC Lagda, C Pietzsch, JSY Ho, ...
Science 352 (6289), aad7993, 2016
1512016
Mechanisms establishing TLR4-responsive activation states of inflammatory response genes
L Escoubet-Lozach, C Benner, MU Kaikkonen, J Lozach, S Heinz, ...
PLoS genetics 7 (12), e1002401, 2011
1512011
Macrophage development from HSCs requires PU. 1-coordinated microRNA expression
S Ghani, P Riemke, J Schönheit, D Lenze, J Stumm, M Hoogenkamp, ...
Blood, The Journal of the American Society of Hematology 118 (8), 2275-2284, 2011
1412011
Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells
M Leddin, C Perrod, M Hoogenkamp, S Ghani, S Assi, S Heinz, ...
Blood, The Journal of the American Society of Hematology 117 (10), 2827-2838, 2011
1412011
Identification of lineage-specific transcription factors that prevent activation of hepatic stellate cells and promote fibrosis resolution
X Liu, J Xu, S Rosenthal, L Zhang, R McCubbin, N Meshgin, L Shang, ...
Gastroenterology 158 (6), 1728-1744. e14, 2020
1342020
IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease
HY Ma, G Yamamoto, J Xu, X Liu, D Karin, JY Kim, LB Alexandrov, ...
Journal of hepatology 72 (5), 946-959, 2020
1332020
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