Giada Mondanelli
Giada Mondanelli
Researcher, Department Medicine and Surgey, University of Perugia
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A relay pathway between arginine and tryptophan metabolism confers immunosuppressive properties on dendritic cells
G Mondanelli, R Bianchi, MT Pallotta, C Orabona, E Albini, A Iacono, ...
Immunity 46 (2), 233-244, 2017
The immune regulation in cancer by the amino acid metabolizing enzymes ARG and IDO
G Mondanelli, S Ugel, U Grohmann, V Bronte
Current opinion in pharmacology 35, 30-39, 2017
Wolfram syndrome, a rare neurodegenerative disease: from pathogenesis to future treatment perspectives
MT Pallotta, G Tascini, R Crispoldi, C Orabona, G Mondanelli, ...
Journal of translational medicine 17, 1-12, 2019
Amino-acid sensing and degrading pathways in immune regulation
U Grohmann, G Mondanelli, ML Belladonna, C Orabona, MT Pallotta, ...
Cytokine & growth factor reviews 35, 37-45, 2017
Polyamines and kynurenines at the intersection of immune modulation
E Proietti, S Rossini, U Grohmann, G Mondanelli
Trends in immunology 41 (11), 1037-1050, 2020
Immunoregulatory interplay between arginine and tryptophan metabolism in health and disease
G Mondanelli, A Iacono, M Allegrucci, P Puccetti, U Grohmann
Frontiers in immunology 10, 1565, 2019
Positive allosteric modulation of indoleamine 2, 3-dioxygenase 1 restrains neuroinflammation
G Mondanelli, A Coletti, FA Greco, MT Pallotta, C Orabona, A Iacono, ...
Proceedings of the National Academy of Sciences 117 (7), 3848-3857, 2020
Forced IDO 1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes
MT Pallotta, C Orabona, R Bianchi, C Vacca, F Fallarino, ML Belladonna, ...
Journal of cellular and molecular medicine 18 (10), 2082-2091, 2014
Amino acid metabolism as drug target in autoimmune diseases
G Mondanelli, A Iacono, A Carvalho, C Orabona, C Volpi, MT Pallotta, ...
Autoimmunity Reviews 18 (4), 334-348, 2019
Distinct roles of immunoreceptor tyrosine‐based motifs in immunosuppressive indoleamine 2, 3‐dioxygenase 1
E Albini, V Rosini, M Gargaro, G Mondanelli, ML Belladonna, MT Pallotta, ...
Journal of cellular and molecular medicine 21 (1), 165-176, 2017
Deficiency of immunoregulatory indoleamine 2, 3-dioxygenase 1 in juvenile diabetes
C Orabona, G Mondanelli, MT Pallotta, A Carvalho, E Albini, F Fallarino, ...
JCI insight 3 (6), 2018
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes
A Fiore, S Ugel, F De Sanctis, S Sandri, G Fracasso, R Trovato, S Sartoris, ...
Nature Communications 9 (1), 5193, 2018
Engagement of nuclear coactivator 7 by 3-hydroxyanthranilic acid enhances activation of aryl hydrocarbon receptor in immunoregulatory dendritic cells
M Gargaro, C Vacca, S Massari, G Scalisi, G Manni, G Mondanelli, ...
Frontiers in Immunology 10, 1973, 2019
Loss of IDO1 expression from human pancreatic β-cells precedes their destruction during the development of type 1 diabetes
F Anquetil, G Mondanelli, N Gonzalez, T Rodriguez Calvo, ...
Diabetes 67 (9), 1858-1866, 2018
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism
F Fallarino, MT Pallotta, D Matino, M Gargaro, C Orabona, C Vacca, ...
Immunobiology 220 (2), 315-321, 2015
The landscape of AhR regulators and coregulators to fine-tune AhR functions
M Gargaro, G Scalisi, G Manni, G Mondanelli, U Grohmann, F Fallarino
International Journal of Molecular Sciences 22 (2), 757, 2021
Assessment of TILs, IDO-1, and PD-L1 in resected non-small cell lung cancer: an immunohistochemical study with clinicopathological and prognostic implications
M Mandarano, G Bellezza, ML Belladonna, BJ Van den Eynde, R Chiari, ...
Virchows Archiv 474, 159-168, 2019
The proteasome inhibitor bortezomib controls indoleamine 2, 3-dioxygenase 1 breakdown and restores immune regulation in autoimmune diabetes
G Mondanelli, E Albini, MT Pallotta, C Volpi, L Chatenoud, C Kuhn, ...
Frontiers in Immunology 8, 428, 2017
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine
CC Clement, A D’Alessandro, S Thangaswamy, S Chalmers, R Furtado, ...
Nature communications 12 (1), 4447, 2021
Indoleamine 2, 3-dioxygenase 2 immunohistochemical expression in resected human non-small cell lung cancer: a potential new prognostic tool
M Mandarano, G Bellezza, ML Belladonna, J Vannucci, A Gili, I Ferri, ...
Frontiers in immunology 11, 839, 2020
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