| Efficacy of the CCR5 antagonist maraviroc in reducing early, ritonavir-induced atherogenesis and advanced plaque progression in mice S Cipriani, D Francisci, A Mencarelli, B Renga, E Schiaroli, C D’Amore, ... Circulation 127 (21), 2114-2124, 2013 | 129 | 2013 |
| VSL# 3 resets insulin signaling and protects against NASH and atherosclerosis in a model of genetic dyslipidemia and intestinal inflammation A Mencarelli, S Cipriani, B Renga, A Bruno, C D'Amore, E Distrutti, ... Public Library of Science 7 (9), e45425, 2012 | 125 | 2012 |
| Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation A Mencarelli, E Distrutti, B Renga, C D'Amore, S Cipriani, G Palladino, ... PLoS One 6 (7), e22978, 2011 | 104 | 2011 |
| Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors C D’Amore, FS Di Leva, V Sepe, B Renga, C Del Gaudio, MV D’Auria, ... Journal of Medicinal Chemistry 57 (3), 937-954, 2014 | 97 | 2014 |
| The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation B Renga, A Mencarelli, S Cipriani, C D'Amore, A Carino, A Bruno, ... PLoS One 8 (1), e54472, 2013 | 97 | 2013 |
| Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands C Festa, B Renga, C D’Amore, V Sepe, C Finamore, S De Marino, ... Journal of medicinal chemistry 57 (20), 8477-8495, 2014 | 86 | 2014 |
| Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis B Renga, A Mencarelli, C D'Amore, S Cipriani, MV D'Auria, V Sepe, ... PLoS One 7 (1), e30443, 2012 | 85 | 2012 |
| Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter B Renga, M Migliorati, A Mencarelli, S Cipriani, C D'Amore, E Distrutti, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1809 (3), 157-165, 2011 | 84 | 2011 |
| Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor V Sepe, G Bifulco, B Renga, C D’Amore, S Fiorucci, A Zampella Journal of medicinal chemistry 54 (5), 1314-1320, 2011 | 80 | 2011 |
| Theonellasterols and Conicasterols from Theonella swinhoei. Novel Marine Natural Ligands for Human Nuclear Receptors S De Marino, R Ummarino, MV D’Auria, MG Chini, G Bifulco, B Renga, ... Journal of medicinal chemistry 54 (8), 3065-3075, 2011 | 76 | 2011 |
| Modification on ursodeoxycholic acid (UDCA) scaffold. Discovery of bile acid derivatives as selective agonists of cell-surface G-protein coupled bile acid receptor 1 (GP-BAR1) V Sepe, B Renga, C Festa, C D’Amore, D Masullo, S Cipriani, FS Di Leva, ... Journal of medicinal chemistry 57 (18), 7687-7701, 2014 | 72 | 2014 |
| CCR5 antagonism by maraviroc reduces the potential for gastric cancer cell dissemination A Mencarelli, L Graziosi, B Renga, S Cipriani, C D'Amore, D Francisci, ... Translational oncology 6 (6), 784-793, 2013 | 65 | 2013 |
| Dissociation of intestinal and hepatic activities of FXR and LXRα supports metabolic effects of terminal ileum interposition in rodents A Mencarelli, B Renga, C D’Amore, C Santorelli, L Graziosi, A Bruno, ... Diabetes 62 (10), 3384-3393, 2013 | 60 | 2013 |
| Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological … FS Di Leva, C Festa, C D’Amore, S De Marino, B Renga, MV D’Auria, ... Journal of Medicinal Chemistry 56 (11), 4701-4717, 2013 | 60 | 2013 |
| Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity V Sepe, R Ummarino, MV D’Auria, A Mencarelli, C D’Amore, B Renga, ... Journal of medicinal chemistry 54 (13), 4590-4599, 2011 | 59 | 2011 |
| Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition B Renga, A Mencarelli, C D'Amore, S Cipriani, F Baldelli, A Zampella, ... The FASEB Journal 26 (7), 3021-3031, 2012 | 58 | 2012 |
| Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei V Sepe, R Ummarino, MV D’Auria, MG Chini, G Bifulco, B Renga, ... Journal of Medicinal Chemistry 55 (1), 84-93, 2012 | 57 | 2012 |
| Plakilactones from the Marine Sponge Plakinastrella mamillaris. Discovery of a New Class of Marine Ligands of Peroxisome Proliferator-Activated Receptor γ C Festa, G Lauro, S De Marino, MV D’Auria, MC Monti, A Casapullo, ... Journal of Medicinal Chemistry 55 (19), 8303-8317, 2012 | 56 | 2012 |
| SHP-dependent and-independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory … B Renga, A Mencarelli, M Migliorati, S Cipriani, C D’Amore, E Distrutti, ... Inflammation Research 60, 577-587, 2011 | 55 | 2011 |
| The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines A Carino, L Graziosi, C D'Amore, S Cipriani, S Marchianò, E Marino, ... Oncotarget 7 (38), 61021, 2016 | 53 | 2016 |
