| Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system R Giri, A Morrone, A Toto, M Brunori, S Gianni Proceedings of the National Academy of Sciences 110 (37), 14942-14947, 2013 | 108 | 2013 |
| Molecular recognition by templated folding of an intrinsically disordered protein A Toto, C Camilloni, R Giri, M Brunori, M Vendruscolo, S Gianni Scientific reports 6 (1), 21994, 2016 | 92 | 2016 |
| Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein S Gianni, C Camilloni, R Giri, A Toto, D Bonetti, A Morrone, P Sormanni, ... Proceedings of the National Academy of Sciences 111 (39), 14141-14146, 2014 | 57 | 2014 |
| Comparing the binding properties of peptides mimicking the Envelope protein of SARS‐CoV and SARS‐CoV‐2 to the PDZ domain of the tight junction‐associated PALS1 protein A Toto, S Ma, F Malagrinò, L Visconti, L Pagano, K Stromgaard, S Gianni Protein Science 29 (10), 2038-2042, 2020 | 55 | 2020 |
| Templated folding of intrinsically disordered proteins A Toto, F Malagrinò, L Visconti, F Troilo, L Pagano, M Brunori, P Jemth, ... Journal of Biological Chemistry 295 (19), 6586-6593, 2020 | 49 | 2020 |
| The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c‐Myb A Toto, R Giri, M Brunori, S Gianni Protein Science 23 (7), 962-969, 2014 | 44 | 2014 |
| Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering D Bonetti, F Troilo, A Toto, M Brunori, S Longhi, S Gianni Biochemistry 56 (29), 3780-3786, 2017 | 31 | 2017 |
| Mutational analysis of the binding-induced folding reaction of the mixed-lineage leukemia protein to the KIX domain A Toto, S Gianni Biochemistry 55 (28), 3957-3962, 2016 | 22 | 2016 |
| The kinetics of folding of frataxin D Bonetti, A Toto, R Giri, A Morrone, D Sanfelice, A Pastore, P Temussi, ... Physical Chemistry Chemical Physics 16 (14), 6391-6397, 2014 | 22 | 2014 |
| Characterization of human frataxin missense variants in cancer tissues M Petrosino, A Pasquo, L Novak, A Toto, S Gianni, E Mantuano, ... Human mutation 40 (9), 1400-1413, 2019 | 20 | 2019 |
| Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins G Malgieri, G D'Abrosca, L Pirone, A Toto, M Palmieri, L Russo, ... Chemical Science 9 (13), 3290-3298, 2018 | 20 | 2018 |
| Mechanism of Folding and Binding of the N-Terminal SH2 Domain from SHP2 D Bonetti, F Troilo, A Toto, C Travaglini-Allocatelli, M Brunori, S Gianni The Journal of Physical Chemistry B 122 (49), 11108-11114, 2018 | 18 | 2018 |
| Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate C Gautier, F Troilo, F Cordier, F Malagrinò, A Toto, L Visconti, Y Zhu, ... Proceedings of the National Academy of Sciences 117 (33), 19963-19969, 2020 | 17 | 2020 |
| Mapping the allosteric network within a SH3 domain F Malagrinò, F Troilo, D Bonetti, A Toto, S Gianni Scientific reports 9 (1), 8279, 2019 | 17 | 2019 |
| Understanding the role of phosphorylation in the binding mechanism of a PDZ domain A Toto, A Mattei, P Jemth, S Gianni Protein Engineering, Design and Selection 30 (1), 1-5, 2016 | 17 | 2016 |
| Activation barrier-limited folding and conformational sampling of a dynamic protein domain J Dogan, A Toto, E Andersson, S Gianni, P Jemth Biochemistry 55 (37), 5289-5295, 2016 | 16 | 2016 |
| Double mutant cycles as a tool to address folding, binding, and allostery L Pagano, A Toto, F Malagrinò, L Visconti, P Jemth, S Gianni International Journal of Molecular Sciences 22 (2), 828, 2021 | 15 | 2021 |
| Unveiling induced folding of intrinsically disordered proteins–protein engineering, frustration and emerging themes F Malagrinò, A Diop, L Pagano, C Nardella, A Toto, S Gianni Current Opinion in Structural Biology 72, 153-160, 2022 | 14 | 2022 |
| Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins EL Cascio, A Toto, G Babini, F De Maio, M Sanguinetti, A Mordente, ... Computational and Structural Biotechnology Journal 19, 1838-1847, 2021 | 14 | 2021 |
| Ligand binding to the PDZ domains of postsynaptic density protein 95 A Toto, SW Pedersen, OA Karlsson, GE Moran, E Andersson, CN Chi, ... Protein Engineering, Design and Selection 29 (5), 169-175, 2016 | 14 | 2016 |
