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Theodoros K Karamanos
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The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism
MG Iadanza, R Silvers, J Boardman, HI Smith, TK Karamanos, ...
Nature Communications 9 (1), 4517, 2018
1272018
pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers
KW Tipping, TK Karamanos, T Jakhria, MG Iadanza, SC Goodchild, ...
Proceedings of the National Academy of Sciences 112 (18), 5691-5696, 2015
1202015
Mechanisms of amyloid formation revealed by solution NMR
TK Karamanos, AP Kalverda, GS Thompson, SE Radford
Progress in nuclear magnetic resonance spectroscopy 88, 86-104, 2015
1162015
Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo
CL Dobson, PWA Devine, JJ Phillips, DR Higazi, C Lloyd, B Popovic, ...
Scientific reports 6 (1), 1-14, 2016
1102016
Visualizing and trapping transient oligomers in amyloid assembly pathways
EE Cawood, TK Karamanos, AJ Wilson, SE Radford
Biophysical chemistry 268, 106505, 2021
992021
Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis
TK Karamanos, V Tugarinov, GM Clore
Proceedings of the National Academy of Sciences 116 (43), 21529-21538, 2019
672019
Visualization of transient protein-protein interactions that promote or inhibit amyloid assembly
TK Karamanos, AP Kalverda, GS Thompson, SE Radford
Molecular cell 55 (2), 214-226, 2014
662014
Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients
AN Calabrese, B Schiffrin, M Watson, TK Karamanos, M Walko, ...
Nature Communications 11 (1), 1-16, 2020
542020
Structural mapping of oligomeric intermediates in an amyloid assembly pathway
TK Karamanos, MP Jackson, AN Calabrese, SC Goodchild, EE Cawood, ...
Elife 8, e46574, 2019
482019
A population shift between sparsely populated folding intermediates determines amyloidogenicity
TK Karamanos, CL Pashley, AP Kalverda, GS Thompson, M Mayzel, ...
Journal of the American Chemical Society 138 (19), 6271-6280, 2016
382016
An S/T motif controls reversible oligomerization of the Hsp40 chaperone DNAJB6b through subtle reorganization of a β sheet backbone
TK Karamanos, V Tugarinov, GM Clore
Proceedings of the National Academy of Sciences 117 (48), 30441-30450, 2020
272020
Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins
EM Martin, MP Jackson, M Gamerdinger, K Gense, TK Karamonos, ...
Journal of Biological Chemistry 293 (22), 8554-8568, 2018
252018
Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation
N Benseny-Cases, TK Karamanos, CL Hoop, J Baum, SE Radford
Journal of Biological Chemistry 294 (24), 9392-9401, 2019
222019
Modulation of amyloidogenic protein self-assembly using tethered small molecules
EE Cawood, N Guthertz, JS Ebo, TK Karamanos, SE Radford, AJ Wilson
Journal of the American Chemical Society 142 (49), 20845-20854, 2020
202020
Structural studies of “aggregation‐prone” peptide‐analogues of teleostean egg chorion ZPB proteins
NN Louros, N Petronikolou, T Karamanos, P Cordopatis, VA Iconomidou, ...
Peptide Science 102 (6), 427-436, 2014
182014
Microsecond backbone motions modulate the oligomerization of the Dnajb6 chaperone
EE Cawood, GM Clore, TK Karamanos
Angewandte Chemie 134 (20), e202116403, 2022
152022
Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding
B Schiffrin, JM Machin, TK Karamanos, A Zhuravleva, DJ Brockwell, ...
Communications Biology 5 (1), 560, 2022
142022
Magic‐Angle‐Pulse Driven Separation of Degenerate 1H Transitions in Methyl Groups of Proteins: Application to Studies of Methyl Axis Dynamics
V Tugarinov, TK Karamanos, GM Clore
ChemPhysChem 21 (11), 1087-1091, 2020
142020
Distinguishing Closely Related Amyloid Precursors Using an RNA Aptamer
CJ Sarell, TK Karamanos, SJ White, DHJ Bunka, AP Kalverda, ...
Journal of Biological Chemistry 289 (39), 26859-26871, 2014
122014
Optimized selection of slow-relaxing 13 C transitions in methyl groups of proteins: application to relaxation dispersion
V Tugarinov, TK Karamanos, GM Clore
Journal of Biomolecular NMR 74 (12), 673-680, 2020
112020
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Articles 1–20