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William Charman
William Charman
Faculty of Pharmacy & Pharmaceutical Sciences, Monash University
Verified email at monash.edu - Homepage
Title
Cited by
Cited by
Year
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
CJH Porter, NL Trevaskis, WN Charman
Nature reviews Drug discovery 6 (3), 231-248, 2007
19722007
Strategies to address low drug solubility in discovery and development
HD Williams, NL Trevaskis, SA Charman, RM Shanker, WN Charman, ...
Pharmacological reviews 65 (1), 315-499, 2013
16562013
Enhancing intestinal drug solubilisation using lipid-based delivery systems
CJH Porter, CW Pouton, JF Cuine, WN Charman
Advanced drug delivery reviews 60 (6), 673-691, 2008
8362008
Lipid-based vehicles for the oral delivery of poorly water soluble drugs
AJ Humberstone, WN Charman
Advanced drug delivery reviews 25 (1), 103-128, 1997
8091997
Physicochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH
WN Charman, CJH Porter, S Mithani, JB Dressman
Journal of pharmaceutical sciences 86 (3), 269-282, 1997
7811997
Identification of an antimalarial synthetic trioxolane drug development candidate
JL Vennerstrom, S Arbe-Barnes, R Brun, SA Charman, FCK Chiu, ...
Nature 430 (7002), 900-904, 2004
7762004
Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound
SA Charman, WN Charman, MC Rogge, TD Wilson, FJ Dutko, CW Pouton
Pharmaceutical research 9, 87-93, 1992
6261992
Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine
SM Khoo, AJ Humberstone, CJH Porter, GA Edwards, WN Charman
International journal of pharmaceutics 167 (1-2), 155-164, 1998
5621998
In vitro assessment of oral lipid based formulations
CJH Porter, WN Charman
Advanced drug delivery reviews 50, S127-S147, 2001
4942001
Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update
NL Trevaskis, WN Charman, CJH Porter
Advanced drug delivery reviews 60 (6), 702-716, 2008
4622008
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
SA Charman, S Arbe-Barnes, IC Bathurst, R Brun, M Campbell, ...
Proceedings of the National Academy of Sciences 108 (11), 4400-4405, 2011
4432011
Intestinal lymphatic drug transport: an update
CJH Porter, WN Charman
Advanced drug delivery reviews 50 (1-2), 61-80, 2001
4012001
Lipids, lipophilic drugs, and oral drug delivery—some emerging concepts
WN Charman
Journal of pharmaceutical sciences 89 (8), 967-978, 2000
3822000
50 years of oral lipid-based formulations: provenance, progress and future perspectives
OM Feeney, MF Crum, CL McEvoy, NL Trevaskis, HD Williams, ...
Advanced drug delivery reviews 101, 167-194, 2016
3722016
Prodrugs: Do they have advantages in clinical practice?
VJ Stella, WNA Charman, VH Naringrekar
Drugs 29, 455-473, 1985
3571985
Effect of short‐, medium‐, and long‐chain fatty acid‐based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of …
SM Caliph, WN Charman, CJH Porter
Journal of pharmaceutical sciences 89 (8), 1073-1084, 2000
3462000
Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products
L Sek, CJH Porter, AM Kaukonen, WN Charman
Journal of pharmacy and pharmacology 54 (1), 29-41, 2002
3422002
Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors …
JM Coteron, M Marco, J Esquivias, X Deng, KL White, J White, M Koltun, ...
Journal of medicinal chemistry 54 (15), 5540-5561, 2011
3182011
The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?
MM Doherty, WN Charman
Clinical pharmacokinetics 41, 235-253, 2002
3012002
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice
R Gujjar, A Marwaha, F El Mazouni, J White, KL White, S Creason, ...
Journal of medicinal chemistry 52 (7), 1864-1872, 2009
2902009
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