| Characterization of a novel glucose-responsive insulin-secreting cell line, BRIN-BD11, produced by electrofusion NH McClenaghan, CR Barnett, E Ah-Sing, YHA Abdel-Wahab, ... Diabetes 45 (8), 1132-1140, 1996 | 408 | 1996 |
| Development and functional characterization of insulin-releasing human pancreatic beta cell lines produced by electrofusion JT McCluskey, M Hamid, H Guo-Parke, NH McClenaghan, R Gomis, ... Journal of Biological Chemistry 286 (25), 21982-21992, 2011 | 160 | 2011 |
| A nuclear magnetic resonance-based demonstration of substantial oxidative l-alanine metabolism and l-alanine-enhanced glucose metabolism in a clonal pancreatic β-cell line … L Brennan, A Shine, C Hewage, JPG Malthouse, KM Brindle, ... Diabetes 51 (6), 1714-1721, 2002 | 150 | 2002 |
| Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line NH McClenaghan, CR Barnett, FPM O'Harte, PR Flatt Journal of Endocrinology 151 (3), 349-357, 1996 | 146 | 1996 |
| Nutrient regulation of insulin secretion and β-cell functional integrity P Newsholme, C Gaudel, NH McClenaghan The islets of Langerhans, 91-114, 2010 | 125 | 2010 |
| A comparative study of amino acid consumption by rat islet cells and the clonal beta-cell line BRIN-BD11-the functional significance of L-alanine G Dixon, J Nolan, N McClenaghan, PR Flatt, P Newsholme Journal of Endocrinology 179 (3), 447, 2003 | 122 | 2003 |
| Glycation of insulin in the islets of Langerhans of normal and diabetic animals YHA Abdel-Wahab, FP O'Harte, H Ratcliff, NH McClenaghan, CR Barnett, ... Diabetes 45 (11), 1489-1496, 1996 | 108 | 1996 |
| Engineering cultured insulin-secreting pancreatic B-cell lines NH McClenaghan, PR Flatt Journal of Molecular Medicine 77, 235-243, 1999 | 107 | 1999 |
| L-arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge MS Krause, NH McClenaghan, PR Flatt, PIH de Bittencourt, C Murphy, ... Journal of Endocrinology 211 (1), 87-97, 2011 | 99 | 2011 |
| Role of islet structure and cellular interactions in the control of insulin secretion C Kelly, NH McClenaghan, PR Flatt Islets 3 (2), 41-47, 2011 | 99 | 2011 |
| 13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and γ-glutamyl cycle activity in a clonal pancreatic beta-cell line L Brennan, M Corless, C Hewage, JPG Malthouse, NH McClenaghan, ... Diabetologia 46, 1512-1521, 2003 | 90 | 2003 |
| Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic beta-cell line A Kiely, NH McClenaghan, PR Flatt, P Newsholme Journal of Endocrinology 195 (1), 113, 2007 | 88 | 2007 |
| Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic β-cell insulin secretion, growth and functional integrity G Dixon, J Nolan, NH McCLENAGHAN, PR Flatt, P Newsholme Clinical science 106 (2), 191-199, 2004 | 82 | 2004 |
| L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic β-cell line and protects from pro-inflammatory cytokine … GA Cunningham, NH Mcclenaghan, PR Flatt, P Newsholme Clinical Science 109 (5), 447-455, 2005 | 81 | 2005 |
| Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion S Patterson, PR Flatt, L Brennan, P Newsholme, NH McClenaghan Journal of endocrinology 189 (2), 301, 2006 | 79 | 2006 |
| Physiological regulation of the pancreatic β‐cell: functional insights for understanding and therapy of diabetes NH McClenaghan Experimental physiology 92 (3), 481-496, 2007 | 73 | 2007 |
| Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic β-cell line M Corless, A Kiely, NH McClenaghan, PR Flatt, P Newsholme Journal of Endocrinology 190 (3), 719-727, 2006 | 72 | 2006 |
| Physiological and pharmacological regulation of insulin release: insights offered through exploitation of insulin-secreting cell lines. NH McClenaghan, PR Flatt Diabetes, Obesity & Metabolism 1 (3), 1999 | 60 | 1999 |
| Cystic fibrosis–related diabetes: pathophysiology and therapeutic challenges R Kelsey, FN Manderson Koivula, NH McClenaghan, C Kelly Clinical Medicine Insights: Endocrinology and Diabetes 12, 1179551419851770, 2019 | 59 | 2019 |
| Cellular responses of novel human pancreatic β-cell line, 1.1 B4 to hyperglycemia S Vasu, NH McClenaghan, JT McCluskey, PR Flatt Islets 5 (4), 170-177, 2013 | 57 | 2013 |
Peter R FlattProfessor, University of UlsterVerified email at ulster.ac.uk
