Impact of the halogen substitution pattern on the biological activity of organoruthenium 8-hydroxyquinoline anticancer agents M Kubanik, H Holtkamp, T Sohnel, SMF Jamieson, CG Hartinger Organometallics 34 (23), 5658-5668, 2015 | 161 | 2015 |
From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents NYS Lam, D Truong, H Burmeister, MV Babak, HU Holtkamp, ... Inorganic chemistry 57 (22), 14427-14434, 2018 | 66 | 2018 |
Characterizing activation mechanisms and binding preferences of ruthenium metallo-prodrugs by a competitive binding assay C Artner, HU Holtkamp, CG Hartinger, SM Meier-Menches Journal of Inorganic Biochemistry 177, 322-327, 2017 | 44 | 2017 |
(Pyridin-2-yl)-NHC organoruthenium complexes: antiproliferative properties and reactivity toward biomolecules S Movassaghi, S Singh, A Mansur, KKH Tong, M Hanif, HU Holtkamp, ... Organometallics 37 (10), 1575-1584, 2018 | 43 | 2018 |
Making organoruthenium complexes of 8-hydroxyquinolines more hydrophilic: impact of a novel L-phenylalanine-derived arene ligand on the biological activity S Movassaghi, M Hanif, HU Holtkamp, T Söhnel, SMF Jamieson, ... Dalton Transactions 47 (7), 2192-2201, 2018 | 40 | 2018 |
Organoruthenium and osmium anticancer complexes bearing a maleimide functional group: Reactivity to cysteine, stability, and cytotoxicity S Moon, M Hanif, M Kubanik, H Holtkamp, T Söhnel, SMF Jamieson, ... ChemPlusChem 80 (1), 231-236, 2015 | 39 | 2015 |
Arsenate–ferrihydrite systems from minutes to months: a macroscopic and IR spectroscopic study of an elusive equilibrium PJ Swedlund, H Holtkamp, Y Song, CJ Daughney Environmental science & technology 48 (5), 2759-2765, 2014 | 37 | 2014 |
DNA or protein? Capillary zone electrophoresis–mass spectrometry rapidly elucidates metallodrug binding selectivity C Artner, HU Holtkamp, W Kandioller, CG Hartinger, SM Meier-Menches, ... Chemical communications 53 (57), 8002-8005, 2017 | 34 | 2017 |
Electrophoretic separation techniques and their hyphenation to mass spectrometry in biological inorganic chemistry H Holtkamp, G Grabmann, CG Hartinger Electrophoresis 37 (7-8), 959-972, 2016 | 29 | 2016 |
Advanced metallomics methods in anticancer metallodrug mode of action studies HU Holtkamp, CG Hartinger TrAC Trends in Analytical Chemistry 104, 110-117, 2018 | 28 | 2018 |
Metallomic study on the metabolism of RAPTA-C and cisplatin in cell culture medium and its impact on cell accumulation HU Holtkamp, S Movassaghi, SJ Morrow, M Kubanik, CG Hartinger Metallomics 10 (3), 455-462, 2018 | 28 | 2018 |
A Bioactive l-Phenylalanine-Derived Arene in Multitargeted Organoruthenium Compounds: Impact on the Antiproliferative Activity and Mode of Action S Movassaghi, E Leung, M Hanif, BYT Lee, HU Holtkamp, JKY Tu, ... Inorganic Chemistry 57 (14), 8521-8529, 2018 | 26 | 2018 |
Antitumor metallodrugs that target proteins MP Sullivan, HU Holtkamp, CG Hartinger Met. Ions Life Sci 18, 351-386, 2018 | 25 | 2018 |
RuII(η6‐p‐cymene) Complexes of Bioactive 1,2‐Benzothiazines: Protein Binding vs. Antitumor Activity A Ashraf, M Kubanik, F Aman, H Holtkamp, T Söhnel, SMF Jamieson, ... European Journal of Inorganic Chemistry 2016 (9), 1376-1382, 2016 | 20 | 2016 |
Analysis of ruthenium anticancer agents by MEEKC‐UV and MEEKC–ICP‐MS: Impact of structural motifs on lipophilicity and biological activity K Giringer, HU Holtkamp, S Movassaghi, WDJ Tremlett, NYS Lam, ... Electrophoresis 39 (9-10), 1201-1207, 2018 | 19 | 2018 |
Capillary electrophoresis in metallodrug development H Holtkamp, CG Hartinger Drug Discovery Today: Technologies 16, 16-22, 2015 | 18 | 2015 |
Quinoline-para-quinones and metals: coordination-assisted formation of quinoline-ortho-quinones M Kubanik, NYS Lam, HU Holtkamp, T Söhnel, RF Anderson, ... Chemical communications 54 (8), 992-995, 2018 | 17 | 2018 |
Raman spectroscopy reveals age-and sex-related differences in cortical bone from people with osteoarthritis MK Nieuwoudt, R Shahlori, D Naot, R Patel, H Holtkamp, C Aguergaray, ... Scientific Reports 10 (1), 19443, 2020 | 13 | 2020 |
Hyphenation of capillary electrophoresis to inductively coupled plasma mass spectrometry with a modified coaxial sheath-flow interface HU Holtkamp, SJ Morrow, M Kubanik, CG Hartinger Journal of Chromatography A 1561, 76-82, 2018 | 12 | 2018 |
F.; Gaiddon, C.; Ott, I.; Hartinger, CG From Catalysis to Cancer: Toward Structure− Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes … NYS Lam, D Truong, H Burmeister, MV Babak, HU Holtkamp, ... Inorg. Chem 57, 14427-14434, 2018 | 11 | 2018 |