| Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors MR Bockman, AS Kalinda, R Petrelli, T De la Mora-Rey, D Tiwari, F Liu, ... Journal of medicinal chemistry 58 (18), 7349-7369, 2015 | 30 | 2015 |
| Mutual potentiation drives synergy between trimethoprim and sulfamethoxazole Y Minato, S Dawadi, SL Kordus, A Sivanandam, CC Aldrich, AD Baughn Nature communications 9 (1), 1-7, 2018 | 28 | 2018 |
| Synthesis and Pharmacokinetic Evaluation of Siderophore Biosynthesis Inhibitors for Mycobacterium tuberculosis KM Nelson, K Viswanathan, S Dawadi, BP Duckworth, HI Boshoff, ... Journal of medicinal chemistry 58 (14), 5459-5475, 2015 | 28 | 2015 |
| Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis S Dawadi, S Kawamura, A Rubenstein, R Remmel, CC Aldrich Bioorganic & medicinal chemistry 24 (6), 1314-1321, 2016 | 20 | 2016 |
| Investigation and conformational analysis of fluorinated nucleoside antibiotics targeting siderophore biosynthesis S Dawadi, K Viswanathan, HI Boshoff, CE Barry III, CC Aldrich The Journal of organic chemistry 80 (10), 4835-4850, 2015 | 19 | 2015 |
| Structure-based optimization of pyridoxal 5′-phosphate-dependent transaminase enzyme (BioA) inhibitors that target biotin biosynthesis in Mycobacterium tuberculosis F Liu, S Dawadi, KM Maize, R Dai, SW Park, D Schnappinger, BC Finzel, ... Journal of medicinal chemistry 60 (13), 5507-5520, 2017 | 18 | 2017 |
| 2-Aryl-8-aza-3-deazaadenosine analogues of 5′-O-[N-(salicyl) sulfamoyl] adenosine: nucleoside antibiotics that block siderophore biosynthesis in Mycobacterium tuberculosis A Krajczyk, J Zeidler, P Januszczyk, S Dawadi, HI Boshoff, CE Barry III, ... Bioorganic & medicinal chemistry 24 (14), 3133-3143, 2016 | 16 | 2016 |
| Anchimerically activated ProTides as inhibitors of cap-dependent translation and inducers of chemosensitization in mantle cell lymphoma A Okon, JJ Han, S Dawadi, C Demosthenous, CC Aldrich, M Gupta, ... Journal of Medicinal Chemistry 60 (19), 8131-8144, 2017 | 15 | 2017 |
| Targeting protein biotinylation enhances tuberculosis chemotherapy D Tiwari, SW Park, MM Essawy, S Dawadi, A Mason, M Nandakumar, ... Science translational medicine 10 (438), eaal1803, 2018 | 14 | 2018 |
| Avoiding Antibiotic Inactivation in Mycobacterium tuberculosis by Rv3406 through Strategic Nucleoside Modification MR Bockman, CA Engelhart, S Dawadi, P Larson, D Tiwari, DM Ferguson, ... ACS infectious diseases 4 (7), 1102-1113, 2018 | 13 | 2018 |
| Conformationally constrained cinnolinone nucleoside analogues as siderophore biosynthesis inhibitors for tuberculosis S Dawadi, HIM Boshoff, SW Park, D Schnappinger, CC Aldrich ACS medicinal chemistry letters 9 (4), 386-391, 2018 | 13 | 2018 |
| Synthesis and analysis of bacterial folate metabolism intermediates and antifolates S Dawadi, SL Kordus, AD Baughn, CC Aldrich Organic letters 19 (19), 5220-5223, 2017 | 12 | 2017 |
| Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library S Dawadi, N Simmons, G Miklossy, KM Bohren, JC Faver, MN Ucisik, ... Proceedings of the National Academy of Sciences 117 (29), 16782-16789, 2020 | 4 | 2020 |
| Chelating compounds and immobilized tethered chelators RA Yokel, WR Harris, CD Spilling, RJ Kuhn, S Dawadi US Patent 9,139,456, 2015 | 4 | 2015 |
| Trapping hemiacetals with phosphono substituted palladium π-allyl complexes for the synthesis of substituted cyclic ethers N Sutivisedsak, S Dawadi, CD Spilling Tetrahedron letters 56 (23), 3534-3537, 2015 | 3 | 2015 |
| Immobilized ligands for the removal of metal ions and methods thereof C Spilling, W Harris, S Dawadi, B Hamper | 3 | 2014 |
| Optimization of guanidinylation of amines for the synthesis of protease-focused DNA-encoded chemical library S Dawadi, N Simmons, M Matzuk ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
| Potentiation of para-aminosalicylic acid (PAS) by chemical inhibition of para-aminobenzoic acid (PABA) biosynthesis in Mycobacterium tuberculosis S Dawadi, Y Minato, A Baughn, C Aldrich ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Synthesis and toxicological analysis of 5'sulfamoylated adenosine scaffolds for MtBPL drug development M Fuller, M Bockman, S Dawadi, C Aldrich ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Avoiding antibiotic inactivation in Mycobacterium tuberculosis through strategic nucleoside modification M Bockman, S Dawadi, C Aldrich ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
Courtney AldrichUniversity of Minnesota, Department of Medicinal ChemistryVerified email at umn.edu
Courtney AldrichUniversity of Minnesota, Department of Medicinal ChemistryVerified email at umn.edu