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David P Breen
David P Breen
Verified email at ed.ac.uk
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Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial
S Palfi, JM Gurruchaga, GS Ralph, H Lepetit, S Lavisse, PC Buttery, ...
The Lancet 383 (9923), 1138-1146, 2014
5112014
Characterizing mild cognitive impairment in incident Parkinson disease: the ICICLE-PD study
AJ Yarnall, DP Breen, GW Duncan, TK Khoo, SY Coleman, MJ Firbank, ...
Neurology 82 (4), 308-316, 2014
4682014
Sleep and circadian rhythm regulation in early Parkinson disease
DP Breen, R Vuono, U Nawarathna, K Fisher, JM Shneerson, AB Reddy, ...
JAMA neurology 71 (5), 589-595, 2014
4112014
S erum immune markers and disease progression in an incident P arkinson's disease cohort (ICICLE‐PD)
CH Williams‐Gray, R Wijeyekoon, AJ Yarnall, RA Lawson, DP Breen, ...
Movement disorders 31 (7), 995-1003, 2016
2572016
Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's
G Liu, B Boot, JJ Locascio, IE Jansen, S Winder‐Rhodes, S Eberly, ...
Annals of neurology 80 (5), 674-685, 2016
2522016
Cognitive decline and quality of life in incident Parkinson's disease: the role of attention
RA Lawson, AJ Yarnall, GW Duncan, DP Breen, TK Khoo, ...
Parkinsonism & related disorders 27, 47-53, 2016
2202016
Cognitive decline and quality of life in incident Parkinson's disease: the role of attention
RA Lawson, AJ Yarnall, GW Duncan, DP Breen, TK Khoo, ...
Parkinsonism & related disorders 27, 47-53, 2016
2202016
Bioinformatics-based identification of expanded repeats: a non-reference intronic pentamer expansion in RFC1 causes CANVAS
H Rafehi, DJ Szmulewicz, MF Bennett, NLM Sobreira, K Pope, KR Smith, ...
The American Journal of Human Genetics 105 (1), 151-165, 2019
1992019
Gut–brain axis and the spread of α‐synuclein pathology: vagal highway or dead end?
DP Breen, GM Halliday, AE Lang
Movement disorders 34 (3), 307-316, 2019
1912019
Genetic impact on cognition and brain function in newly diagnosed Parkinson’s disease: ICICLE-PD study
C Nombela, JB Rowe, SE Winder-Rhodes, A Hampshire, AM Owen, ...
Brain 137 (10), 2743-2758, 2014
1892014
Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life
RA Lawson, AJ Yarnall, GW Duncan, TK Khoo, DP Breen, RA Barker, ...
Parkinsonism & related disorders 20 (10), 1071-1075, 2014
1702014
Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts
G Liu, JJ Locascio, JC Corvol, B Boot, Z Liao, K Page, D Franco, K Burke, ...
The Lancet Neurology 16 (8), 620-629, 2017
1472017
Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease
G Hudson, M Nalls, JR Evans, DP Breen, S Winder-Rhodes, KE Morrison, ...
Neurology 80 (22), 2042-2048, 2013
1422013
Genetic risk of Parkinson disease and progression: an analysis of 13 longitudinal cohorts
H Iwaki, C Blauwendraat, HL Leonard, G Liu, J Maple-Grødem, JC Corvol, ...
Neurology: Genetics 5 (4), e348, 2019
1352019
The Addenbrooke's Cognitive Examination for the differential diagnosis and longitudinal assessment of patients with parkinsonian disorders
T Rittman, BC Ghosh, P McColgan, DP Breen, J Evans, CH Williams-Gray, ...
Journal of Neurology, Neurosurgery & Psychiatry 84 (5), 544-551, 2013
1242013
Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation
DP Breen, AM Marinaki, M Arenas, PC Hayes
Liver transplantation 11 (7), 826-833, 2005
1172005
Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts
H Iwaki, C Blauwendraat, HL Leonard, JJ Kim, G Liu, J Maple‐Grødem, ...
Movement Disorders 34 (12), 1839-1850, 2019
1122019
Driving and dementia
DA Breen, DP Breen, JW Moore, PA Breen, D O'Neill
BMJ 334 (7608), 1365-1369, 2007
1092007
Neuroendocrine abnormalities in Parkinson's disease
E De Pablo-Fernández, DP Breen, PM Bouloux, RA Barker, T Foltynie, ...
Journal of Neurology, Neurosurgery & Psychiatry 88 (2), 176-185, 2017
932017
Determinants of delayed diagnosis in Parkinson’s disease
DP Breen, JR Evans, K Farrell, C Brayne, RA Barker
Journal of neurology 260, 1978-1981, 2013
882013
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