| Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent … J Jacobs, V Grum-Tokars, Y Zhou, M Turlington, SA Saldanha, P Chase, ... Journal of medicinal chemistry 56 (2), 534-546, 2013 | 207 | 2013 |
| Ligand-induced dimerization of Middle East respiratory syndrome (MERS) coronavirus nsp5 protease (3CLpro): implications for nsp5 regulation and the development of antivirals S Tomar, ML Johnston, SES John, HL Osswald, PR Nyalapatla, LN Paul, ... Journal of Biological Chemistry 290 (32), 19403-19422, 2015 | 152 | 2015 |
| Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity CC Stobart, NR Sexton, H Munjal, X Lu, KL Molland, S Tomar, ... Journal of virology 87 (23), 12611-12618, 2013 | 147 | 2013 |
| Discovery of N-(benzo [1, 2, 3] triazol-1-yl)-N-(benzyl) acetamido) phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors … M Turlington, A Chun, S Tomar, A Eggler, V Grum-Tokars, J Jacobs, ... Bioorganic & medicinal chemistry letters 23 (22), 6172-6177, 2013 | 131 | 2013 |
| Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4—The likely reservoir host to the human coronavirus that causes Middle … SES John, S Tomar, SR Stauffer, AD Mesecar Bioorganic & medicinal chemistry 23 (17), 6036-6048, 2015 | 99 | 2015 |
| The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein KA Fontaine, KE Leon, MM Khalid, JM David, S Tomar, M Dunlap, ... bioRxiv, 2018 | 64 | 2018 |
| A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant S Agnihothram, BL Yount Jr, EF Donaldson, J Huynh, VD Menachery, ... MBio 5 (2), 10.1128/mbio. 00047-14, 2014 | 57 | 2014 |
| Structure-function studies of DNA binding domain of response regulator KdpE reveals equal affinity interactions at DNA half-sites A Narayanan, LN Paul, S Tomar, DN Patil, P Kumar, DA Yernool PloS one 7 (1), e30102, 2012 | 31 | 2012 |
| Development of highly effective anti-mesothelin hYP218 chimeric antigen receptor T cells with increased tumor infiltration and persistence for treating solid tumors S Tomar, J Zhang, M Khanal, J Hong, A Venugopalan, Q Jiang, ... Molecular cancer therapeutics 21 (7), 1195-1206, 2022 | 21 | 2022 |
| Low expression of RNA sensors impacts Zika virus infection in the lower female reproductive tract S Khan, I Lew, F Wu, L Fritts, KA Fontaine, S Tomar, M Trapecar, ... Nature communications 10 (1), 4344, 2019 | 12 | 2019 |
| The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein. mBio 9: e02126-18 KA Fontaine, KE Leon, MM Khalid, S Tomar, D Jimenez-Morales, ... | 9 | 2018 |
| Crystallization and preliminary X-ray diffraction analysis of the complex of Kunitz-type tamarind trypsin inhibitor and porcine pancreatic trypsin S Tomar, DN Patil, M Datta, S Tapas, A Chaudhary, AK Sharma, P Kumar Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 7 | 2009 |
| Expression, purification, crystallization and preliminary crystallographic studies of cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase from Pandoraea pnomenusa B-356 KP Tomar Sakshi, Patil DN, Tomar S, Sylvestre M Acta Crystallographica Section F 66 (11), 1517-1520, 2010 | 4 | 2010 |
| A BAF’ling Approach to Curing HIV S Tomar, I Ali, M Ott Cell Chemical Biology 25 (12), 1441-1442, 2018 | 3 | 2018 |
| Understanding the determinants for substrate recognition, regulation of enzymatic activity and the development of broad-spectrum inhibitors of coronavirus 3-chymotrypsin-like … S Tomar Purdue University, 2015 | 3 | 2015 |
| Zika virus infection prevents host mRNA nuclear export by disrupting UPF1 function K Leon, R Flynn, MM Khalid, KA Fontaine, T Nguyen, GR Kumar, ... bioRxiv, 2020.12. 03.410837, 2020 | 2 | 2020 |
| Nuclear accumulation of host transcripts during Zika Virus Infection KE Leon, MM Khalid, RA Flynn, KA Fontaine, TT Nguyen, GR Kumar, ... PLoS pathogens 19 (1), e1011070, 2023 | 1 | 2023 |
| Development of Mouse Hepatitis Virus Chimeric Reporter Viruses Expressing the 3CLpro Proteases of Human Coronaviruses HKU1 and OC43 Reveals Susceptibility to Inactivation by … ER Huffman, JX Franges, JM Doster, AR Armstrong, YS Batista, ... COVID 4 (2), 208-220, 2024 | | 2024 |
| hYP218 CAR-T cells targeting a membrane-proximal epitope of mesothelin are highly effective against mesothelin expressing cancers S Tomar, J Zhang, N Li, I Pastan, M Ho, R Hassan Cancer Research 82 (12_Supplement), 5567-5567, 2022 | | 2022 |
| AICTE VIDEO CONFERENCE K Namdev, K Patel, S Tomar, YS Chouhan, S Khan | | |
Andrew D. MesecarDistinguished Professor of Biochemistry, Purdue University, Department of BiochemistryVerified email at purdue.edu
