Adriano Aguzzi

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Glatzel, MProfessor of Neuropathology Institute of Neuropathology, University Medical Center Hamburg-EppendorfVerified email at uke.de
Frank HeppnerDept. of Neuropathology, Charité - Universitätsmedizin BerlinVerified email at charite.de
Marco PrinzProfessor of Neuropathology, University Hospital FreiburgVerified email at uniklinik-freiburg.de
Magdalini PolymenidouAssociate Professor for Biomedicine, Department of Quantitative Biomedicine, University of ZurichVerified email at imls.uzh.ch
Christina J. SigurdsonUC San DiegoVerified email at ucsd.edu
Andreas W. SailerNovartisVerified email at novartis.com
Tuomas KnowlesProfessor of Physical Chemistry and Biophysics, University of CambridgeVerified email at cam.ac.uk
Karl FrontzekUniversity College London, Institute of NeurologyVerified email at ucl.ac.uk
Herbert BudkaProfessor of Neuropathol., ret., Med. Univ. Vienna, AustriaVerified email at meduniwien.ac.at
Paul KleihuesMedical Faculty, University of ZurichVerified email at pathol.uzh.ch
Caihong ZhuInstitute of Neuropathology, University Hospital of ZürichVerified email at usz.ch
Michel AguetEcole Polytechnique Fédérale de Lausanne (EPFL)Verified email at epfl.ch
Burkhard BecherUniversity of ZurichVerified email at immunology.uzh.ch
David Paul WolferUniversity of Zurich and ETH ZurichVerified email at uzh.ch
Dr. Frank BaumannHertie Institute for Clinical Brain ResearchVerified email at uni-tuebingen.de
Professor Nataraj Kav, Ph.D., FRSB., F...Department of Agricultural Food and Nutritional ScienceVerified email at ualberta.ca
Christopher DobsonUniversity of CambridgeVerified email at cam.ac.uk
Gregor HutterAttending physician, Neurosurgery, University Hospital BaselVerified email at usb.ch
Samuel GandyIcahn School of Medicine at Mount SinaiVerified email at mssm.edu
Maurizio PocchiariIstituto Superiore di SanitàVerified email at iss.it

Adriano Aguzzi

Professor of Neuropathology at University Zurich

Verified email at usz.ch - Homepage

prions neurodegeneration neuropathology


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Mice devoid of PrP are resistant to scrapie H Büeler, A Aguzzi, A Sailer, RA Greiner, P Autenried, M Aguet, ... Cell 73 (7), 1339-1347, 1993	2592	1993
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud F Bladt, D Riethmacher, S Isenmann, A Aguzzi, C Birchmeier Nature 376, 768-771, 1995	1577	1995
An analytical solution to the kinetics of breakable filament assembly TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ... Science 326 (5959), 1533-1537, 2009	1095	2009
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. TJ Cole, JA Blendy, AP Monaghan, K Krieglstein, W Schmid, A Aguzzi, ... Genes & development 9 (13), 1608-1621, 1995	1080	1995
Prion protein (PrP) with amino‐proximal deletions restoring susceptibility of PrP knockout mice to scrapie. M Fischer, T Rülicke, A Raeber, A Sailer, M Moser, B Oesch, S Brandner, ... The EMBO journal 15 (6), 1255-1264, 1996	1052	1996
Normal host prion protein necessary for scrapie-induced neurotoxicity S Brandner, A Raeber, M Fischer, A Sailer, Y Kobayashi, ... Nature 379, 25, 1996	950	1996
Microglia: scapegoat, saboteur, or something else? A Aguzzi, BA Barres, ML Bennett Science 339 (6116), 156-161, 2013	922	2013
Experimental autoimmune encephalomyelitis repressed by microglial paralysis FL Heppner, M Greter, D Marino, J Falsig, G Raivich, N Hövelmeyer, ... Nature medicine 11 (2), 146-152, 2005	876	2005
Protein aggregation diseases: pathogenicity and therapeutic perspectives A Aguzzi, T O'connor Nature reviews Drug discovery 9 (3), 237-248, 2010	814	2010
Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase. YL Yang, LF Reis, J Pavlovic, A Aguzzi, R Schäfer, A Kumar, BR Williams, ... The EMBO journal 14 (24), 6095-6106, 1995	809	1995
Mammalian prion biology: one century of evolving concepts A Aguzzi, M Polymenidou Cell 116 (2), 313-327, 2004	745	2004
The adaptor ASC has extracellular and'prionoid'activities that propagate inflammation BS Franklin, L Bossaller, D De Nardo, JM Ratter, A Stutz, G Engels, ... Nature immunology 15 (8), 727-737, 2014	723	2014
p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases K Zatloukal, C Stumptner, A Fuchsbichler, H Heid, M Schnoelzer, ... The American journal of pathology 160 (1), 255-263, 2002	680	2002
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. B Adams, P Dörfler, A Aguzzi, Z Kozmik, P Urbanek, I Maurer-Fogy, ... Genes & development 6 (9), 1589-1607, 1992	646	1992
The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice S Calogero, F Grassi, A Aguzzi, T Voigtländer, P Ferrier, S Ferrari, ... Nature genetics 22 (3), 276-280, 1999	644	1999
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members S Heber, J Herms, V Gajic, J Hainfellner, A Aguzzi, T Rülicke, ... Journal of Neuroscience 20 (21), 7951-7963, 2000	627	2000
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions D Shmerling, I Hegyi, M Fischer, T Blättler, S Brandner, J Götz, T Rülicke, ... Cell 93 (2), 203-214, 1998	626	1998
A crucial role for B cells in neuroinvasive scrapie MA Klein, R Frigg, E Flechsig, AJ Raeber, U Kalinke, H Bluethmann, ... Nature 390 (6661), 687-690, 1997	624	1997
Prions: protein aggregation and infectious diseases A Aguzzi, AM Calella Physiological reviews 89 (4), 1105-1152, 2009	604	2009
Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors. U Günther, J Benson, D Benke, JM Fritschy, G Reyes, F Knoflach, ... Proceedings of the National Academy of Sciences 92 (17), 7749-7753, 1995	550	1995

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