Adriano Aguzzi
Adriano Aguzzi
Professor of Neuropathology at University Zurich
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Mice devoid of PrP are resistant to scrapie
H Büeler, A Aguzzi, A Sailer, RA Greiner, P Autenried, M Aguet, ...
Cell 73 (7), 1339-1347, 1993
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud
F Bladt, D Riethmacher, S Isenmann, A Aguzzi, C Birchmeier
Nature 376 (6543), 768-771, 1995
An analytical solution to the kinetics of breakable filament assembly
TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ...
Science 326 (5959), 1533-1537, 2009
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.
TJ Cole, JA Blendy, AP Monaghan, K Krieglstein, W Schmid, A Aguzzi, ...
Genes & development 9 (13), 1608-1621, 1995
Prion protein (PrP) with amino‐proximal deletions restoring susceptibility of PrP knockout mice to scrapie.
M Fischer, T Rülicke, A Raeber, A Sailer, M Moser, B Oesch, S Brandner, ...
The EMBO journal 15 (6), 1255-1264, 1996
Microglia: scapegoat, saboteur, or something else?
A Aguzzi, BA Barres, ML Bennett
Science 339 (6116), 156-161, 2013
Normal host prion protein necessary for scrapie-induced neurotoxicity
S Brandner, A Raeber, M Fischer, A Sailer, Y Kobayashi, ...
Nature 379, 25, 1996
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
FL Heppner, M Greter, D Marino, J Falsig, G Raivich, N Hövelmeyer, ...
Nature medicine 11 (2), 146-152, 2005
Protein aggregation diseases: pathogenicity and therapeutic perspectives
A Aguzzi, T O'connor
Nature reviews Drug discovery 9 (3), 237-248, 2010
Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase.
YL Yang, LF Reis, J Pavlovic, A Aguzzi, R Schäfer, A Kumar, BR Williams, ...
The EMBO journal 14 (24), 6095-6106, 1995
The adaptor ASC has extracellular and'prionoid'activities that propagate inflammation
BS Franklin, L Bossaller, D De Nardo, JM Ratter, A Stutz, G Engels, ...
Nature immunology 15 (8), 727-737, 2014
Mammalian prion biology: one century of evolving concepts
A Aguzzi, M Polymenidou
Cell 116 (2), 313-327, 2004
p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases
K Zatloukal, C Stumptner, A Fuchsbichler, H Heid, M Schnoelzer, ...
The American journal of pathology 160 (1), 255-263, 2002
The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice
S Calogero, F Grassi, A Aguzzi, T Voigtländer, P Ferrier, S Ferrari, ...
Nature genetics 22 (3), 276-280, 1999
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
B Adams, P Dörfler, A Aguzzi, Z Kozmik, P Urbanek, I Maurer-Fogy, ...
Genes & development 6 (9), 1589-1607, 1992
Prions: protein aggregation and infectious diseases
A Aguzzi, AM Calella
Physiological reviews 89 (4), 1105-1152, 2009
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members
S Heber, J Herms, V Gajic, J Hainfellner, A Aguzzi, T Rülicke, ...
Journal of Neuroscience 20 (21), 7951-7963, 2000
A crucial role for B cells in neuroinvasive scrapie
MA Klein, R Frigg, E Flechsig, AJ Raeber, U Kalinke, H Bluethmann, ...
Nature 390 (6661), 687-690, 1997
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
D Shmerling, I Hegyi, M Fischer, T Blättler, S Brandner, J Götz, T Rülicke, ...
Cell 93 (2), 203-214, 1998
The AP-1 transcription factor c-Jun is required for efficient axonal regeneration
G Raivich, M Bohatschek, C Da Costa, O Iwata, M Galiano, M Hristova, ...
Neuron 43 (1), 57-67, 2004
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