|Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy|
JC Jha, SP Gray, D Barit, J Okabe, A El-Osta, T Namikoshi, ...
Journal of the American Society of Nephrology 25 (6), 1237-1254, 2014
|Diabetes and kidney disease: role of oxidative stress|
JC Jha, C Banal, BSM Chow, ME Cooper, K Jandeleit-Dahm
Antioxidants & redox signaling 25 (12), 657-684, 2016
|miR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7|
AD McClelland, M Herman-Edelstein, R Komers, JC Jha, CE Winbanks, ...
Clinical Science 129 (12), 1237-1249, 2015
|Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b|
B Wang, JC Jha, S Hagiwara, AD McClelland, K Jandeleit-Dahm, ...
Kidney international 85 (2), 352-361, 2014
|Oxidative stress, Nox isoforms and complications of diabetes—potential targets for novel therapies|
M Sedeek, AC Montezano, RL Hebert, SP Gray, E Di Marco, JC Jha, ...
Journal of cardiovascular translational research 5 (4), 509-518, 2012
|Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy|
V Thallas‐Bonke, JC Jha, SP Gray, D Barit, H Haller, HHHW Schmidt, ...
Physiological reports 2 (11), e12192, 2014
|Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy|
JC Jha, V Thallas-Bonke, C Banal, SP Gray, BSM Chow, G Ramm, ...
Diabetologia 59 (2), 379-389, 2016
|NADPH oxidase Nox5 accelerates renal injury in diabetic nephropathy|
JC Jha, C Banal, J Okabe, SP Gray, T Hettige, BSM Chow, ...
Diabetes 66 (10), 2691-2703, 2017
|Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno-and atheroprotection even in established micro-and macrovascular disease|
SP Gray, JC Jha, K Kennedy, E Van Bommel, P Chew, C Szyndralewiez, ...
Diabetologia 60 (5), 927-937, 2017
|Are reactive oxygen species still the basis for diabetic complications?|
ED Marco, JC Jha, A Sharma, JL Wilkinson-Berka, KA Jandeleit-Dahm, ...
Clinical Science 129 (2), 199-216, 2015
|A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes|
JC Jha, F Ho, C Dan, K Jandeleit-Dahm
Clinical Science 132 (16), 1811-1836, 2018
|New insights into the use of biomarkers of diabetic nephropathy|
JC Jha, KAM Jandeleit-Dahm, ME Cooper
Advances in chronic kidney disease 21 (3), 318-326, 2014
|The emerging role of NADPH oxidase NOX5 in vascular disease|
JC Jha, AMD Watson, G Mathew, LC de Vos, K Jandeleit-Dahm
Clinical Science 131 (10), 981-990, 2017
|A study of oxidative stress, antioxidant status and lipid profile in diabetic patient in the western region of Nepal.|
BR Maharjan, JC Jha, D Adhikari, P Vishwanath, J Baxi, VM Alurkar, ...
Kathmandu University medical journal (KUMJ) 6 (1), 16-22, 2008
|Oxidative stress, antioxidant status and lipid profile in ischemic heart disease patients from western region of Nepal.|
BR Maharjan, JC Jha, D Adhikari, S Risal, VM Alurkar, PP Singh
Nepal Medical College journal: NMCJ 10 (1), 20-24, 2008
|Cigarette smoke induced oxidative insult in local population of Pokhara.|
JC Jha, BR Maharjan, D Adhikari, P Vishwanath, T Nagamma, S Azhari, ...
Kathmandu University medical journal (KUMJ) 5 (4), 511-517, 2007
|Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse|
JC Jha, A Dai, CE Holterman, ME Cooper, RM Touyz, CR Kennedy, ...
Diabetologia 62 (9), 1712-1726, 2019
|NADPH oxidase inhibition: preclinical and clinical studies in diabetic complications|
S Urner, F Ho, JC Jha, D Ziegler, K Jandeleit-Dahm
Antioxidants & redox signaling 33 (6), 415-434, 2020
|Nox (nadph oxidase) 1, nox4, and nox5 promote vascular permeability and neovascularization in retinopathy|
D Deliyanti, SF Alrashdi, RM Touyz, CR Kennedy, JC Jha, ME Cooper, ...
Hypertension 75 (4), 1091-1101, 2020
|Oxidant-antioxidant status and lipid profile in the hypertensive patients|
PP Singh, VM Alurkar, BR Maharjan, JR Jha, P Vishwanath
Journal of Nepal Health Research Council, 2008